Protein
Postreplication repair E3 ubiquitin-protein ligase rad18
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Function
E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.
Similarity
Belongs to the RAD18 family.
Sequence
MEPTFDIPDSTDWLDTPLTLLAPFETSLRCQVCKDFFDNPVITSCSHTFCSLCIRRCLSTEGKCPTCRSSDQELKLRRNWVVQELVEGFKNARPSILQLARMAQTGTDDSGDLAAEEPASKKRKIEPNAIVGTDGLPEEGIRTRSQSRGASRQPQATPVQVIDDGNDEDYMPDGLVPCPVCGRRMKEEAVFRHLDSCTGTAEELKPAAFGSLAPGPRKSFLAATGKPPERLPVINYSLLKDTVLRKKLKDLGIPNWGPRALLQRRHTEWLNLWNANCDSRTPKPKRELLRELDVWERTQGGNSVTPTDPTNAVMNKDFNTEEWSANYDTDFKALIANARKKNDAVIRSTIPNASQANSDTPRSAQLVDQPIEASLTPQDVDEKSTMNPQDAIDNRTEVPPVPDPPQALSGIDRAVNSPMKNVTEGDAQAIPISSSASTHKTPH