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uvrD2

Gene
uvrD2
Protein
ATP-dependent DNA helicase UvrD2
Organism
Mycobacterium leprae (strain TN)
Length
714 amino acids
Function
DNA-dependent ATPase, stimulated equally by ss-and dsDNA. Has both ATPase and helicase activities (By similarity).
Similarity
Belongs to the helicase family. UvrD subfamily.
Mass
77.343 kDa
Sequence
MVMVVNPLTAGLDDEQREAVLAPRGPVCVLAGAGTGKTRTITHRIAHLVGAGHVATGQVLAVTFTQRAAAEMRSRLRALGAAVQAVSDFGVVRVLTFHAAAHRQLRYFWPRVIGDTGWQLLDSKFATVARAASSVRLHAGTDDVCDLAGEIEWAKASLIGPEEYVAAVAAIGRDTPLDAAQIASVYAAYEALKARGNGVPGVTLLDFDDLLLHTAAAIENDAAVAEEFRDRYRCFVVDEYQDVTPLQQRVLSAWLGDRDDLTVVGDANQTIYSFTGASPCFLLDFPRRFPDATVVRLERDYRSTPQVVSLANQVIAAAHGRVADSKFQLSGQREPGPAASFHEYSDEPAEAAAVAASIARLIEFGTSPSEIAVLYRVNAQSEAYEEALTEVGIAYQVRGGEGFFNRQEIKQALLALQRSAERSSQTEPNSPLSDVVRGVLEPLGLTAEKPVGSRARDRWEALTALAELADDEVAQHPRLDLPGLLAELRLRADARHPPVVQGVTLASLHAVKGLEWDAVFLVGLADGTLPISRALAHGAESEPVEEERRLLYVGITRARVYLALSWALSRTPGGRQSRKPSRFLNDIAPQMGQNPASSRSRRNRTATLRCRICKNDLTTPAAVMLQRCQICAADVDEELLLQLKAWRLSTAKEQNVPAYVVLTDNTLIAIAELLPADEAALIAVPGMSVRKIEQYGSDVLQLVRCRAVAVRTQT

Gene
uvrD2
Protein
ATP-dependent DNA helicase UvrD2
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Length
700 amino acids
Function
DNA-dependent ATPase, stimulated equally by ss-and dsDNA. Has both ATPase and helicase activities (By similarity).
Similarity
Belongs to the helicase family. UvrD subfamily.
Mass
75.604 kDa
Sequence
MSIASDPLIAGLDDQQREAVLAPRGPVCVLAGAGTGKTRTITHRIASLVASGHVAAGQVLAVTFTQRAAGEMRSRLRALDAAARTGSGVGAVQALTFHAAAYRQLRYFWSRVIADTGWQLLDSKFAVVARAASRTRLHASTDDVRDLAGEIEWAKASLIGPEEYVTAVAAARRDPPLDAAQIAAVYSEYEALKARGDGVTLLDFDDLLLHTAAAIENDAAVAEEFQDRYRCFVVDEYQDVTPLQQRVLSAWLGDRDDLTVVGDANQTIYSFTGASPRFLLDFSRRFPDAAVVRLERDYRSTPQVVSLANRVIAAARGRVAGSKLRLSGQREPGPVPSFHEHSDEPAEAATVAASIARLIASGTPPSEVAILYRVNAQSEVYEEALTQAGIAYQVRGGEGFFNRQEIKQALLALQRVSERDTDAALSDVVRAVLAPLGLTAQPPVGTRARERWEALTALAELVDDELAQRPALQLPGLLAELRRRAEARHPPVVQGVTLASLHAAKGLEWDAVFLVGLADGTLPISHALAHGPNSEPVEEERRLLYVGITRARVHLALSWALSRSPGGRQSRKPSRFLNGIAPQTRADPVPGTSRRNRGAAARCRICNNELNTSAAVMLRRCETCAADVDEELLLQLKSWRLSTAKEQNVPAYVVFTDNTLIAIAELLPTDDAALIAIPGIGARKLEQYGSDVLQLVRGRT

Gene
uvrD2
Protein
ATP-dependent DNA helicase UvrD2
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
700 amino acids
Function
DNA-dependent ATPase, stimulated equally by ss-and dsDNA. Has both ATPase and helicase activities, and translocates along ssDNA displacing bound streptavidin. Its essentiality for growth does not depend on its helicase activity (By similarity).
Similarity
Belongs to the helicase family. UvrD subfamily.
Mass
75.604 kDa
Sequence
MSIASDPLIAGLDDQQREAVLAPRGPVCVLAGAGTGKTRTITHRIASLVASGHVAAGQVLAVTFTQRAAGEMRSRLRALDAAARTGSGVGAVQALTFHAAAYRQLRYFWSRVIADTGWQLLDSKFAVVARAASRTRLHASTDDVRDLAGEIEWAKASLIGPEEYVTAVAAARRDPPLDAAQIAAVYSEYEALKARGDGVTLLDFDDLLLHTAAAIENDAAVAEEFQDRYRCFVVDEYQDVTPLQQRVLSAWLGDRDDLTVVGDANQTIYSFTGASPRFLLDFSRRFPDAAVVRLERDYRSTPQVVSLANRVIAAARGRVAGSKLRLSGQREPGPVPSFHEHSDEPAEAATVAASIARLIASGTPPSEVAILYRVNAQSEVYEEALTQAGIAYQVRGGEGFFNRQEIKQALLALQRVSERDTDAALSDVVRAVLAPLGLTAQPPVGTRARERWEALTALAELVDDELAQRPALQLPGLLAELRRRAEARHPPVVQGVTLASLHAAKGLEWDAVFLVGLADGTLPISHALAHGPNSEPVEEERRLLYVGITRARVHLALSWALSRSPGGRQSRKPSRFLNGIAPQTRADPVPGTSRRNRGAAARCRICNNELNTSAAVMLRRCETCAADVDEELLLQLKSWRLSTAKEQNVPAYVVFTDNTLIAIAELLPTDDAALIAIPGIGARKLEQYGSDVLQLVRGRT

Gene
uvrD2
Protein
ATP-dependent DNA helicase UvrD2
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
700 amino acids
Function
DNA-dependent ATPase, stimulated equally by ss-and dsDNA. Has both ATPase and helicase activities, and translocates along ssDNA displacing bound streptavidin. Its essentiality for growth does not depend on its helicase activity.
Similarity
Belongs to the helicase family. UvrD subfamily.
Mass
75.604 kDa
Sequence
MSIASDPLIAGLDDQQREAVLAPRGPVCVLAGAGTGKTRTITHRIASLVASGHVAAGQVLAVTFTQRAAGEMRSRLRALDAAARTGSGVGAVQALTFHAAAYRQLRYFWSRVIADTGWQLLDSKFAVVARAASRTRLHASTDDVRDLAGEIEWAKASLIGPEEYVTAVAAARRDPPLDAAQIAAVYSEYEALKARGDGVTLLDFDDLLLHTAAAIENDAAVAEEFQDRYRCFVVDEYQDVTPLQQRVLSAWLGDRDDLTVVGDANQTIYSFTGASPRFLLDFSRRFPDAAVVRLERDYRSTPQVVSLANRVIAAARGRVAGSKLRLSGQREPGPVPSFHEHSDEPAEAATVAASIARLIASGTPPSEVAILYRVNAQSEVYEEALTQAGIAYQVRGGEGFFNRQEIKQALLALQRVSERDTDAALSDVVRAVLAPLGLTAQPPVGTRARERWEALTALAELVDDELAQRPALQLPGLLAELRRRAEARHPPVVQGVTLASLHAAKGLEWDAVFLVGLADGTLPISHALAHGPNSEPVEEERRLLYVGITRARVHLALSWALSRSPGGRQSRKPSRFLNGIAPQTRADPVPGTSRRNRGAAARCRICNNELNTSAAVMLRRCETCAADVDEELLLQLKSWRLSTAKEQNVPAYVVFTDNTLIAIAELLPTDDAALIAIPGIGARKLEQYGSDVLQLVRGRT