Protein
Netrin receptor UNC5B-a
Function
Plays a role in cell-cell adhesion during embryonic development. Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity).
Similarity
Belongs to the unc-5 family.
Sequence
MYLSRNPSGAALAAILVALILSCNFPSSTAGIEYSDVLPDSFPSAPAESLPHFLLEPEDAYIVKNKPVELVCKANPATQIYFKCNGEWVNQNDHITKERVDDVTGLVVREVQIEVSRQQVEELFGLEDYWCQCVAWSSAGTTKSKRSYVRIAYLRKNFDQEPLGKEVALEQEALLQCRPPEGVPPAEVEWLKNEEIIDPTKDTNFLITIDHNLIIKQARLSDTANYTCVSKNIVAKRRSTTATVIVFVNGGWSSWTEWSPCNNRCGHGWQKRTRTCTNPAPLNGGTMCEGQQYQKFACNTMCPVDGGWTEWSKWSACSTECTHWRSRECNAPTPKNGGKDCSGMLLDSKNCTDGLCMQNKRVLGETKSRLLESTGDVALYAGLVVAIFIVIILLMAVGIVVYRRNCREFDTDITDSSAALTGGFHPVNFKTSRHDNSQLIHPAMQPDLTANAGIYRGNMYALQDSADKIPMTNSPLLDPLPNLKIKVYNSSTVGSSPGIHDGNNLLGTKPTGTYPSDNNIMNARNKNMSMQHLLTLPRDSSNSVTGTFGSLGGRLTFPNTGVSLLIPQGAIPQGKYYEMYLMINKRENTVLPSEGTQTILSPIITCGPTGLLLCKPVILTVPHCADINTSDWILQLKTQSHQGNWEEVVTLNEETLNTPCYCQLESHSCHTLLDQLGTYAFVGESYSRSAIKRLQLAIFAPMLCTSLEYNLKVYCVEDTPDALKEVLELEKTLGGYLVEEPKLLMFKDSYHNLRLSIHDIPHSLWRSKLMAKYQEIPFYHIWSGSQRTLHCTFTLERYSLAATELTCKICVRQVEGEGQIFQLHTLLEENVKSFDPFCSQAENSVTTHLGPYAFKIPFSIRQKICNSLDAPNSRGNDWRLLAQKLCMDRYLNYFATKASPTGVILDLWEALHQDDGDLNTLASALEEMGKSEMMLVMATDGDC