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unc-95

Gene
unc-95
Protein
LIM domain-containing protein unc-95
Organism
Caenorhabditis elegans
Length
350 amino acids
Function
Required for the assembly and integrity of muscle dense bodies, which establish the adhesion sites of the muscle cells to the extracellular matrix (PubMed:15210732, PubMed:20385102). Decreased localization of unc-95 to dense bodies and their subsequent dissociation plays an important role in ecdysis during molting (PubMed:20385102). Involved in the organization of the muscle sarcomeric structure and thereby required for locomotion (PubMed:15210732).
Mass
40.457 kDa
Sequence
MTISPQPSHQQFESYQWTTESRSSQQRHGTGTPSQDGRLSAIPDPVERHVARWRSESRNSNKDKVFRNDEEFSQQDEIVNGTLTALKNDVEQTTEIIRRKQEQMRMERRQFQTEMEVNGRISIDPTDDWLAARLKAVSSDDMNQQLVKLKQDQRQNAVTDTLAALVYDVNATTEVLRRGQRGRDGEDGNKKKKEEIEYTLRLTPAPEEQIPQRPKIPEDDNMETDDYSRQYGVQMSEETDSLRRRRARSTTPRRTLHISGSPPPPAAAVCAYCSEEIDGAILTALAPNSERAQKFHTYHFMCTYCQKALNMHGTYREHDLKPYCHDCFYKLYNGLQYAPDDHQASIEKLI