Protein
NEDD8-conjugating enzyme ubc-12
Organism
Caenorhabditis elegans
Function
Accepts the ubiquitin-like protein NEDD8 from the uba-3-ula-1 E1 complex and catalyzes its covalent attachment to other proteins.
Similarity
Belongs to the ubiquitin-conjugating enzyme family. UBC12 subfamily.
Sequence
MFNLQKRINGNNEDGRYLETRIAVRDKLLAQELQQLETALRDQKQKLWHLEVPSTSCLHELELTVTPQEGIYRGGKFRFKITVPPEYNNVPPVVKCLTKVWHPNINEDGSICLSILRQNSLDQYGWRPTRNLTDVVHGLVSLFNDLMDFNDALNIQAAQMWSQNRESFNHRVREYISRYC