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tyrR

Gene
tyrR
Protein
Transcriptional regulatory protein TyrR
Organism
Enterobacter agglomerans
Length
521 amino acids
Function
Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalanine concentrations (By similarity).
Mass
59.023 kDa
Sequence
MRLEVFCQDRIGLARELLDLLVARSIDLRGIEVAASGRIYLNFSTLEFEQFSNLMAEIRRTPGVTDVRTVPYMPSEREHRVLSALLVAMPEPVFSVDLRTKVELANPAAQNLFNLDENKIRNFTADHLINGFNFARWLESERVQAQAQHVVIEGRDFLMEAHPIYLSEDNDQADQLVGAMVMLKSTARMGRQLQNLVVTDETEFDHIVAVTPRMRQVVEQARKLAMHDAPLLIIGDTGTGKDMLARACHLRSARGKMPFLALNCASLPDDVAESELFGHAAGAYPNALEGKKGFFEQANGGSVLLDEIGEMSPTMQTKLLRFLNDGTFRRVGEEHEVHVNVRVICATQKNLFELVQRGEFREDLFYRLNVLTLNLPPLRERVQDIMPLTEIFVARFADEQGIPRPRLSSQLNAFLMRYNWPGNVRQLKNALYRALTQLEGHELRPQDIVLPEQALDVSLGEEAMEGTLDQITSRFERSILTRLYLSYPSTRKLAKRLGVSHTAIANKLREYGLGQKRGDNE

Gene
tyrR
Protein
Transcriptional regulatory protein TyrR
Organism
Citrobacter braakii
Length
514 amino acids
Function
Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalanine concentrations (By similarity).
Mass
57.863 kDa
Sequence
MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFTNFSSLMAEIRRISGVTDVRTVPWMPSEREHLALSALLEALPEPVLSLDMKSKIEMANPASCQLFAHTQDRMRNHTAAQLINGFNFQRWLESNPQDSHSEHVVINGQNFLMEITPVHLQGENQEQMLTGAVVMLRSTIRMGRQLQNMTTQDLSAFSQIIAVSAKMKHVVEQARKLATLSAPLLITGNTGTGKDLFAHACHLASPRASKPYLALNCASIPEDAVESELFGHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQTKLLRFLNDGTFRRVGEDHEVHVDVRVICATQKNLVEMVQKGLFREDLYYRLNVLTLNLPPLRDLPADIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRHVKNAIYRALTQLEGYELRPQDILLPDYDAATVAVGEEVMEGSLDEITSRFERSVLTQLYMNYPSTRKLAKRLGVSHTAIANKLREYGLSQQKKSEE

Gene
tyrR
Protein
Transcriptional regulatory protein TyrR
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
513 amino acids
Function
Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalanine concentrations (By similarity).
Mass
57.68 kDa
Sequence
MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFTDFSSLMAEIRRISGVTDVRTVPWMPSEREHLALSALLEALPEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLDGNPQSSHNEHVVINGQNFLMEITPVHLQNENDEYVLTGAVVMLRSTIRMGQQLQNLSTQDLSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAATVAVGEDAMEGSLDDITSRFERSVLTQLYRSYPSTRKLAKRLGVSHTAIANKLREYGLSQKKGEE

Gene
tyrR
Protein
Transcriptional regulatory protein TyrR
Organism
Escherichia coli (strain K12)
Length
513 amino acids
Function
Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalanine concentrations.
Mass
57.656 kDa
Sequence
MRLEVFCEDRLGLTRELLDLLVLRGIDLRGIEIDPIGRIYLNFAELEFESFSSLMAEIRRIAGVTDVRTVPWMPSEREHLALSALLEALPEPVLSVDMKSKVDMANPASCQLFGQKLDRLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQNFLMEITPVYLQDENDQHVLTGAVVMLRSTIRMGRQLQNVAAQDVSAFSQIVAVSPKMKHVVEQAQKLAMLSAPLLITGDTGTGKDLFAYACHQASPRAGKPYLALNCASIPEDAVESELFGHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEVHVDVRVICATQKNLVELVQKGMFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLAADLNTVLTRYAWPGNVRQLKNAIYRALTQLDGYELRPQDILLPDYDAATVAVGEDAMEGSLDEITSRFERSVLTQLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQKKNEE

Gene
tyrR
Protein
Transcriptional regulatory protein TyrR
Organism
Salmonella typhi
Length
513 amino acids
Function
Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalanine concentrations (By similarity).
Mass
57.68 kDa
Sequence
MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFTDFSSLMAEIRRISGVTDVRTVPWMPSEREHLALSALLEALPEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLDGNPQSSHNEHVVINGQNFLMEITPVHLQNENDEYVLTGAVVMLRSTIRMGQQLQNLSTQDLSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAATVAVGEDAMEGSLDDITSRFERSVLTQLYRSYPSTRKLAKRLGVSHTAIANKLREYGLSQKKGEE

Gene
tyrR
Protein
Transcriptional regulatory protein TyrR
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Length
318 amino acids
Function
Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport.
Mass
35.954 kDa
Sequence
MTISKFNPQKPFECFIVQSEAMKSAVENAKRFAMFDAPLLIQGETGSGKDLLAKACHYQSLRRDKKFIAVNCAGLPDEDAESEMFGRKVGDSETIGFFEYANKGTVLLDGIAELSLSLQAKLLRFLTDGSFRRVGEEKEHYANVRVICTSQVPLHLLVEQGKVRADLFHRLNVLTINVPALRDRMADIEPLAQGFLQEISEELKIAKPTFDKDFLLYLQKYDWKGNVRELYNTLYRACSLVQDNHLTIESLNLALPQSAVISLDEFENKTLDEIIGFYEAQVLKLFYAEYPSTRKLAQRLGVSHTAIANKLKQYGIGK