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twsg1b

Gene
twsg1b
Protein
Twisted gastrulation protein homolog 1-B
Organism
Danio rerio
Length
222 amino acids
Function
Involved in dorsal-ventral patterning. Appears to function predominantly as a ventralizing factor, through its actions as a BMP signaling agonist, acting through both chd-dependent and chd-independent mechanisms. May also antagonize BMP signaling, probably via formation of ternary complexes with chd and BMPs, resulting in dorsalization.
Similarity
Belongs to the twisted gastrulation protein family.
Mass
24.54 kDa
Sequence
MGSSSSSSVVLLLLLLSSLSIALACNKALCASDVSKCLIQELCQCRPADGNCSCCKECMLCLGSLWEECCDCVGMCNPRSMSESPATGRSTVEDLFQPIPSLFRALTEGDAPTHTLVLTLPLAEELQYQHNLHNYLETLHNTQHNNTTSVPENSIHSSYHTQDKQCTVVYFDECVSIRQCKQYCESMGGSKYRWFHNACCQCIGPECVDYGSKSVRCLNCLY