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tut-2

Gene
tut-2
Protein
Cytoplasmic tRNA 2-thiolation protein 2
Organism
Caenorhabditis briggsae
Length
349 amino acids
Function
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with tut-1/ctu-1 that ligates sulfur from thiocarboxylated urm-1 onto the uridine of tRNAs at wobble position.
Similarity
Belongs to the CTU2/NCS2 family.
Mass
39.892 kDa
Sequence
MNFNNFTSDLNGKTCVKCEKEAKFTGVDPKKAWYCQECFIQMVRNKFRSALSKKKIYKEADARDTLVVYDGSPSGTFLLNQIDDALKQITYKRLMVKPTVLVLVSESEEPEIQQVIKRVAEIKKNFLENVNWFIAHIAFCLYDEPSELKEFECNGIEKITAYKYLLASCSVPTYKKELERMLKEKCLQKLAESLKVTKCMVTDDADDLGRLALDQLCLGRGGSLSSLVTVAEKRNDFMIIRPLCDLSKREISIYNYLCKIDDHYIQFSHTQSQEKSVQTLTDAFIRTLEDEKFYSTINTVLSTASKIHNTNGKDGSRCSMCYVEVAEFQCETCSAVRNSCSENLNIIFS

Gene
tut-2
Protein
Cytoplasmic tRNA 2-thiolation protein 2
Organism
Caenorhabditis elegans
Length
349 amino acids
Function
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with tut-1/ctu-1 that ligates sulfur from thiocarboxylated urm-1 onto the uridine of tRNAs at wobble position.
Similarity
Belongs to the CTU2/NCS2 family.
Mass
39.412 kDa
Sequence
MELGNFVTDLNGKKCVKCDKDAKFTGVDPKKAWYCQECFVQMVRNKFRSSLSKKKIYKDADARDTLIVFDGTLSGTFLLHQINDALKQITYKRLMVKPTVLVLVSLTEDTEIQMVIKRIQEIKKSVLENVRWVVAHLACSMYDEDFKLKENECNGVEKISDYNQLIASCSVPTYRKELERVLKEKCLQKIACSMGILKCMVPDHADDLGRLAIDQLCLGRGGSISTLVTVTDKRPDFMLIRPLCDISKKELAVYNYLCDIDKHCIHIAQQNNQQKSVQTLTDAFICTLENEKFYSTINTVLSTAAKIHNTSIGKDDSKCSFCNVEVADSVCSTCSAIRECTGDLLTLLF

Gene
tut-2
Protein
Cytoplasmic tRNA 2-thiolation protein 2
Organism
Caenorhabditis briggsae
Length
349 amino acids
Function
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with tut-1/ctu-1 that ligates sulfur from thiocarboxylated urm-1 onto the uridine of tRNAs at wobble position.
Similarity
Belongs to the CTU2/NCS2 family.
Mass
39.892 kDa
Sequence
MNFNNFTSDLNGKTCVKCEKEAKFTGVDPKKAWYCQECFIQMVRNKFRSALSKKKIYKEADARDTLVVYDGSPSGTFLLNQIDDALKQITYKRLMVKPTVLVLVSESEEPEIQQVIKRVAEIKKNFLENVNWFIAHIAFCLYDEPSELKEFECNGIEKITAYKYLLASCSVPTYKKELERMLKEKCLQKLAESLKVTKCMVTDDADDLGRLALDQLCLGRGGSLSSLVTVAEKRNDFMIIRPLCDLSKREISIYNYLCKIDDHYIQFSHTQSQEKSVQTLTDAFIRTLEDEKFYSTINTVLSTASKIHNTNGKDGSRCSMCYVEVAEFQCETCSAVRNSCSENLNIIFS

Gene
tut-2
Protein
Cytoplasmic tRNA 2-thiolation protein 2
Organism
Caenorhabditis elegans
Length
349 amino acids
Function
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with tut-1/ctu-1 that ligates sulfur from thiocarboxylated urm-1 onto the uridine of tRNAs at wobble position.
Similarity
Belongs to the CTU2/NCS2 family.
Mass
39.412 kDa
Sequence
MELGNFVTDLNGKKCVKCDKDAKFTGVDPKKAWYCQECFVQMVRNKFRSSLSKKKIYKDADARDTLIVFDGTLSGTFLLHQINDALKQITYKRLMVKPTVLVLVSLTEDTEIQMVIKRIQEIKKSVLENVRWVVAHLACSMYDEDFKLKENECNGVEKISDYNQLIASCSVPTYRKELERVLKEKCLQKIACSMGILKCMVPDHADDLGRLAIDQLCLGRGGSISTLVTVTDKRPDFMLIRPLCDISKKELAVYNYLCDIDKHCIHIAQQNNQQKSVQTLTDAFICTLENEKFYSTINTVLSTAAKIHNTSIGKDDSKCSFCNVEVADSVCSTCSAIRECTGDLLTLLF