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ttuB

Gene
ttuB
Protein
Putative tartrate transporter
Organism
Agrobacterium vitis
Length
449 amino acids
Function
Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase.
Similarity
Belongs to the major facilitator superfamily. Phthalate permease family.
Mass
48.395 kDa
Sequence
MQAQEVRLLYLFREDGVVTNDLEARVLRKITFRIVPFIMLLYFIAFLDRVNIGFAALTMNQDLGFSSTVFGIGAGIFFVGYFLFEVPSNLILNKVGARIWIARVMITWGIVSGLMAFVQGTTSFYILRFLLGVAEAGFFPGIILYLSFWFPARRRAAVTALFMAAAPLSTVLGSPISGALMEMHGLMGLAGWQWMFLIEAAPALILGVVVLFFLTDRPEKAKWLTEEERNWLVKTMNAEQAGRGTASHSVMAGLADIRVIALALVYFGTSAGLYTLGIWAPQIIKQFGLSAIEVGFINAVPGIFAVVAMVLWARHSDRTGERTWHVVGACLLAAAGLAFAAGATSVFMVLIALTIVNVGISCSKPPLWSMPTMFLSGPAAAAGIATINSIGNLGGFVGPSMIGWIKDTTGSFTGGLYFVAGLLLISAILTLILARSSPKAVETRTANQH

Gene
ttuB
Protein
Putative tartrate transporter
Organism
Agrobacterium vitis
Length
433 amino acids
Function
Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase.
Similarity
Belongs to the major facilitator superfamily. Phthalate permease family.
Mass
46.253 kDa
Sequence
MNSDLETRVLRKITLRIVPFIMLLYFVAFLDRVNIGFAALTMNEDLGFSSTVFGIGAGIFFVGYFLFEVPSNLILNKVGARIWIARVMITWGIVSGLMAFVQGTTSFYALRFLLGVAEAGFFPGIILYLSFWFPARRRAAVTAIFMAAAPLSTVLGSPISGALMEMHGFLGLAGWQWMFLIEAAPAVILGVVVLFYLTDRPEKAKWLSEDERNWLVKTMNAEQAAKGKASHSILAGLADIRVIALALVYFGTSAGLYTLGIWAPQIIKEFGLSSLQVGFINAVPGIFAVAAMVLWARHSDKTGERTWHVVGACLLAAVGLAFATGATSVFTVLIALTLVNIGISCSKPPLWSMPTLFLSGPAAAAGIATINSIGNLGGFVGPSMIGWIKDTTGSFAGGLYFVAGLLVVSAIVTLVLSRTAPENGGKVAPVQHR

Gene
ttuB
Protein
Sulfur carrier protein TtuB
Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length
65 amino acids
Function
Required for the 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2-thiouridine (m(5)s(2)U or s(2)T) (PubMed:16547008, PubMed:28439027). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is essential for cell growth at high temperatures (PubMed:16547008). Thiocarboxylated TtuB functions as the sulfur donor in the sulfurtransferase reaction catalyzed by TtuA (PubMed:28439027, PubMed:19037260). TtuB also functions as a protein modifier covalently attached to lysine residues of the target proteins TtuA and TtuC (PubMed:22467871). TtuB conjugation might play a regulatory role to ensure appropriate sulfur transfer in cells (PubMed:22467871).
Similarity
Belongs to the TtuB family.
Mass
7.31 kDa
Sequence
MRVVLRLPERKEVEVKGNRPLREVLEELGLNPETVVAVRGEELLTLEDEVREEDTLEVLSAISGG