ttc19

Tetratricopeptide repeat protein 19, mitochondrial

403 amino acids

Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1. Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation into the complex III and whose presence is detrimental for its catalytic activity.

Belongs to the TTC19 family.

45.132 kDa

MALRSYCRQLAAQVFRLKLCGNECPRNAPGCSFSLAGIKSLHEPTGVLARSSRCVKRWHRRSWHRCASLQMPSQKSHSDTTDFSRWTLAWGAVAFSLFGGSDEKTEEQKLEDELILLLKKAKYSMMIGELDAADGFLHRAVRLAHQMHNNDAIIYTYSLMANLAFVRGQLDNAEKLFKAAMSFMLSGGTPQDDNALIEMSLKLASIYATQNKNELAEHGFQFCTDSLEAKMDKQKDLPPESLSDEERKDTRLLLGLSLDARARYLAANHRFIGACRDYRHALQICQEEQGESHPQTLVLMSDLATVLDLRGKHDEALVYVKKAVELGQAAGHPEQHVLLGNMAGILMHNGEFEESAKLYQEALALAHTAGDAEAIEQLQEGLKELDNRRNAKDNSKVEDELKE

TTC19

Tetratricopeptide repeat protein 19, mitochondrial

380 amino acids

Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1 (PubMed:21278747, PubMed:28673544). Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation of UQCRFS1 into the complex III and whose presence is detrimental for its catalytic activity (PubMed:28673544).

Belongs to the TTC19 family.

42.457 kDa

MFRLLSWSLGRGFLRAAGRRCRGCSARLLPGLAGGPGPEVQVPPSRVAPHGRGPGLLPLLAALAWFSRPAAAEEEEQQGADGAAAEDGADEAEAEIIQLLKRAKLSIMKDEPEEAELILHDALRLAYQTDNKKAITYTYDLMANLAFIRGQLENAEQLFKATMSYLLGGGMKQEDNAIIEISLKLASIYAAQNRQEFAVAGYEFCISTLEEKIEREKELAEDIMSVEEKANTHLLLGMCLDACARYLLFSKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLARQINHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKKDEISVQHIREELAELSKKSRPLTNSVKL

Ttc19

Tetratricopeptide repeat protein 19 homolog, mitochondrial

369 amino acids

Required for mitochondrial complex III formation.

Belongs to the TTC19 family.

42.06 kDa

MLVRNICKFTQVMGRFRVVVNPRDYCHLAPLKRSRYHQRSEFGCRPLCSNAAGYEVSWAAPPASGSSGGMFWAFSAAFTLNLFGGADEKEETPEEKLIKTIKRSILCIQREQYDKAEQMLHLALRMAQDIQSKDGITYVFDLMANLAMEREQFKKAEKIFTDVMKRLFAEGHTEESPKILHISSKIAHMSQLQGDLEKSFQGFTWTLQQLAKLLEKMPDDKDILELYGLTKNWFGQLLMKQGKYLEAKNLFKEAFDTLINVYGAVNDASVTILNNISVAYVNLEKYAEARETLLEAMELTKELKDATQEGILQANLGLVYLREGLMSQAENACRLAWKLGKQHQNPDAVEQAEYCLNEIKTTLNGEKRQ

Ttc19

Tetratricopeptide repeat protein 19, mitochondrial

365 amino acids

Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1 (PubMed:21278747, PubMed:28673544). Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation into the complex III and whose presence is detrimental for its catalytic activity (PubMed:28673544).

Belongs to the TTC19 family.

41.234 kDa

MFRLLRWRLGRTLLRAAGRRCGGCTARLLPERTGDAGTGAERLRTRGAPARGHGVLPLLAALAWFSRPAATAEQPGEDASDEAEAEIIQLLKQAKLSIMKDEPEAAELILHDALRLAYESDNRKAITYTYDLMANLAFIRGQLENAEQLFKATMSYLLGGGMKQEDNAIIEISLKLANIYAAQNKQEFALAGYEFCISTLEGKIEREKELAEDIMSEETANTYLLLGMCLDSCARYLLFSKQLSQAQRMYEKALQICQEIQGERHPQTIVLMSDLATTLDAQGHFDDAYIYMQRASDLAREINHPELHMVLSNLAAILIHRERYTQAKEIYQEALKRAELKRDEVSVQHIREELAELSRKSRRLT

Ttc19

Tetratricopeptide repeat protein 19, mitochondrial

365 amino acids

Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1. Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation into the complex III and whose presence is detrimental for its catalytic activity.

Belongs to the TTC19 family.

41.333 kDa

MFRLLRWRLGRTLLRAAGRRCGGCTARLLPERAGDAGPGAERLRTRGAPARGHRVLPLLAALAWFSRTAAAEEQPGEDATDEAEAEIIQLLKRAKLSIMKDEPEAAELILHDALRLAYESDNKKAITYTYDLMANLAFIRGQLENAEQLFKATMSYLLGGGMKQEDNAIVEISLKLANIYAAQNKQEFALAGYEFCISTLEGKIEREKELAEDIMSEERANTYLLLGMCLDSCARYLLFSKQLSQAQRMYEKALQICQEIQGERHPQTIVLMSDLATALDAQGHFDDAYIYMQRASDLAREINHPELHMVLSNLAAILIHRERYTQAKEIYQEALKQAELKRDEFSVQHIREELAELSRKSRLLT