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tsp-21

Gene
tsp-21
Protein
Tetraspanin-21
Organism
Caenorhabditis elegans
Length
301 amino acids
Function
Regulates cell fate specification in the postembryonic mesodermal M lineage and body size, probably by positively modulating BMP-like Sma/Mab signaling at the ligand-receptor level. Promotes ventral fate specification in the M lineage, probably by positively modulating lin-12/Notch signaling.
Similarity
Belongs to the tetraspanin (TM4SF) family.
Mass
34.408 kDa
Sequence
MIDLKSIWNDKRKITYFFLANVCFLISGLSSLIVGVWLYSSKNNFIELTPTSYSALSAAGLCVFTGVTIFIIVAVGYLGVSWSNKSLLYSYIGFVILLILVHGIARITGSLHKEEAKENLRKSMLHNINTTAVVTKIGREIKLSLTWDHLQRELQCCGVDNYTDWHYSVHWPNNLYTPDSCCDPQHFDAENGTENCGKLPDEQSLLYQKGCFPKFSDWLYHHIILVNWVTSILFVVEILLLILSLVVLRVLKNSRHKTRRSHRERDPETTSENMRLNSMDRIADARLETDTVEDGMSINSR