trm14

tRNA (guanine(6)-N2)-methyltransferase

392 amino acids

S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the methylation of the guanosine nucleotide at position 6 (m2G6) in tRNA.

Belongs to the methyltransferase superfamily.

44.374 kDa

MKRVQNLLVAVGLSPNYHRRTYPSGKKSLVVRFYATLTPGLEDVAAKEVESFGCKVEEIRERRGRIFFSGEKSAIPLLNHFSRTLERLNVLLLRCEVEGLDDIYAAVKGLDFSFVKGKSFAIRSLRVGEHDFTSMDIARVAGQAVIDSFMESYGERLKVNLNQPDVIIRVELVDSELFVGVDTTGDDAMHKRWWRVYNHPAHLNAAIACGMLRIADWKVDESLIDPMCGSGTIPIEAALMVRNVPNLRDFAYKKLCEWELAFEPNEVRLKLYGMEKFRKHLVGAIRNAVNAGVADTIEFRQGDATEMTGEYDVIITNPPYGLRIHRKGAIERLYHSFARAAKRCMNQNSRLVIITAEHRVFANAAEEAGLQCTHERFVKYGGLLTKIMVFMI

trm14

tRNA (guanine(6)-N2)-methyltransferase

381 amino acids

S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the methylation of the guanosine nucleotide at position 6 (m2G6) in tRNA(Cys).

Belongs to the methyltransferase superfamily.

43.738 kDa

MDYYVTLSPGLEKISKNEIESFGGKIKEIRENKGRIFFSGDLKLIPKINYLSRTIERMNILLHREEIPNIALDDIYKRVYNIDWTEWIKENQSFAIRPLRAGEHNFTSIDIGRVAGEAVIKSYQRDKNIRLKVNLDEPDVIVRVEVIFDELIVGIDTTGDIALDKRGYRVFNHPAHLNATIASSLVYLSDWKDDEMLLDPMCGSGTIPIEGALMKRNIPPGKFRENKYGFKFIDIFGYELLDKIKKEIVENKNIYKIIGLDKNQKYLDGAKDNAKNAEVLDTIEFICGDATKLHEKFNESDVIIANPPYGIRIGSKRSVKKLYDEFLSSAKEIMHGSSRLIVITAEDKMFKDAIAKNNFEVKEEFNVMFGGLMTRVFYLTL

trm14

tRNA (guanine(6)-N2)-methyltransferase

365 amino acids

S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the methylation of the guanosine nucleotide at position 6 (m2G6) in tRNA(Phe).

Belongs to the methyltransferase superfamily.

41 kDa

MKFLLTTAQGIEDIAKREVSLLLKKLGISFQIEEKPLGIEGRLLLEAEKAYYVDEKGRKRELSISTYLNENSRLLHRVIIEIASEKFNGIEKDESEEALKRIKDFVSSLPVEQFVKVSETFAVRSFRKGDHNITSIDIARTVGEAIFERLSRFGTPLVNLDHPAVIFRAELIKDVFFLGIDTTGDSSLHKRPWRVYDHPAHLKASIANAMIELAELDGGSVLDPMCGSGTILIELALRRYSGEIIGIEKYRKHLIGAEMNALAAGVLDKIKFIQGDATQLSQYVDSVDFAISNLPYGLKIGKKSMIPDLYMKFFNELAKVLEKRGVFITTEKKAIEEAIAENGFEIIHHRVIGHGGLMVHLYVVK