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trh

Gene
trh
Protein
Protein trachealess
Organism
Drosophila melanogaster
Length
1022 amino acids
Function
Transcription factor, master regulator of tracheal cell fates in the embryo, necessary for the development of the salivary gland duct and the posterior spiracles. It may induce a general fate of branched tubular structures of epithelial origin. Heterodimers of tgo/trh are involved in the control of breathless expression.
Mass
109.26 kDa
Sequence
MLPYQAAVAMDYAGYQRQPTPGHPGSHMATMGSLGMPAVPFTHSWMVPTQDLCAMPPYNKMTGHQQPPGAGMHAQQQPLEPGILELRKEKSRDAARSRRGKENYEFYELAKMLPLPAAITSQLDKASIIRLTISYLKLRDFSGHGDPPWTREASSSSKLKSAAIRRSPAVDLFEQHQGTHILQSLDGFALAVAADGRFLYISETVSIYLGLSQVEMTGSSIFDYIHQADHSEIADQLGLSLTSGGGGGGGSSSSGGGGGGAGGGMASPTSGASDDGSGTHGTNNPDVAASMTQASTSGYKGYDRSFCVRMKSTLTKRGCHFKSSGYRASDATSNCNNGNNASNNAKNVKNPGSNYSVVLLLCKLRPQYTFSHSRKSQPPLLGMVALAIALPPPSVHEIRLECDMFVTRVNFDLRVAHCEPRVSDLLDYSPEDLVNKSLYSLCHAEDANRLRKSHSDLIEKGQVLTGYYRLMNKSGGYTWLQTCATVVCSTKNADEQNIICVNYVISNRENENMILDCCQLEPSPDSIKHEEGLGNDKSSGSPGGDASGEGNSHLSAGDMKLNSPKTDSEGHSHRGRGRSAAASHGSSMNSLTMIKDSPTPLGVEIDSGVLPTTVATPVPAATPPVQSTKRKRKTKASQHAEDQGQEQVISEQPLPKLPTMEQRDQQPRSRLPSIVDEQPSSAADSAVKDLEQAMSKHLPSPAAVVSVAPPNTDFSADSLLKQQQQQQQLDPNEKSSTIQWIGTPYQQPPAPMPATALLRQLYANRESVIRATARQTPTGVGPGVFYGDQQTGPLPTPPGSESSYENQYLQLHSAASGGHPGGQKTSADAFTNLVSTYGGYHSSIDYHNAMTPPSSVSPRDSNQPGKAAPVLASNGGYDYAPDPLRGQYATSSGDVVPATLPLKPQASYTATMHPSGSTTTEGGVTYSNLDQPQYFAPHSSFHLYHKGSPASGWYSTPSXVVDDQGQVPPSCQDQYHHHHHHHHHQDGSAGSSASQASERWDFVGALGKVARMFFSARKGNPG

Gene
TRH
Protein
Pro-thyrotropin-releasing hormone
Organism
Gallus gallus
Length
260 amino acids
Function
Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
Similarity
Belongs to the TRH family.
Mass
30.337 kDa
Sequence
MPSIQLPVLLLCLTLSGVCLNGRQFPPELSENMGRSSLDDILQRSGSHMLQSVLKKVEKKEEMNKELNMPLPQWLSKRQHPGKRYISDPEKRQHPGKRDVEEKASFGDIQKRQHLGKTEVEGYLVNYLELKKRQHPGRRSLWDQSTDISSSQLTYLNELSKRQHPGRRYLMYKHQHPSKRGWNDELDLSDQNWEKHQQFGNRDRDSDSPDYTGPCDLQQSAICNKDSLLLDLAEKFSKEGVEEKHQHPGRRSAWENETEE

Gene
Trh
Protein
Pro-thyrotropin-releasing hormone
Organism
Mus musculus
Length
256 amino acids
Function
Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
Similarity
Belongs to the TRH family.
Mass
29.195 kDa
Sequence
MQGPWLMMALALIFVLTGIPKSCALLEAAQEEGAVTPDLPGLEKVQVRPERRFLRKDLQRVRGDLGAALDSWITKRQHPGKREEKEEDVEAEERGDLGEVGAWRPHKRQHPGRRANQDKDSWSDEGDSDWLPPSWLPDFFLDSWFSDAPQVKRQHPGRRSFPWMESDVTKRQHPGRRFIDPELQRSWEETEGEEGGLMPEKRQHPGKRAVGHPCGPQGICGQTGLLQLLGDLSRGQETLAKQTPQLEAWVREPLEE

Gene
Trh
Protein
Pro-thyrotropin-releasing hormone
Organism
Rattus norvegicus
Length
255 amino acids
Function
Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
Similarity
Belongs to the TRH family.
Mass
29.284 kDa
Sequence
MPGPWLLLALALIFTLTGIPESCALPEAAQEEGAVTPDLPGLENVQVRPERRFLWKDLQRVRGDLGAALDSWITKRQHPGKREEEEKDIEAEERGDLGEGGAWRLHKRQHPGRRANQDKYSWADEEDSDWMPRSWLPDFFLDSWFSDVPQVKRQHPGRRSFPWMESDVTKRQHPGRRFIDPELQRSWEEKEGEGVLMPEKRQHPGKRALGHPCGPQGTCGQTGLLQLLGDLSRGQETLVKQSPQVEPWDKEPLEE

Gene
TRH
Protein
Pro-thyrotropin-releasing hormone
Organism
Homo sapiens
Length
242 amino acids
Function
As a component of the hypothalamic-pituitary-thyroid axis, it controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation. It also operates as modulator of hair growth. It promotes hair-shaft elongation, prolongs the hair cycle growth phase (anagen) and antagonizes its termination (catagen) by TGFB2. It stimulates proliferation and inhibits apoptosis of hair matrix keratinocytes.
Similarity
Belongs to the TRH family.
Mass
27.404 kDa
Sequence
MPGPWLLLALALTLNLTGVPGGRAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGKRALGGPCGPQGAYGQAGLLLGLLDDLSRSQGAEEKRQHPGRRAAWVREPLEE

Gene
trh
Protein
Pro-thyrotropin-releasing hormone
Organism
Carassius auratus
Length
231 amino acids
Function
Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
Similarity
Belongs to the TRH family.
Mass
26.597 kDa
Sequence
MRAACVIILASLTVFMSPGLQCQPLAGEGDPSLDELFQRAESLLIRSILTQTEDENHGDGEQTEWLEKRQHPGKRQHPGKREDTDYEDEAAALQKRQHPGKREEEEDSARLRRQHPGKRLSLEHMMLEEPTAQSELAKRQHPGRRYLMLLHKRQHPGRRELHEAAGDFSDLAKRQHPGKRLCEDWDVTGCDQASILLELLDNVNKSRAEEKRQHPGKRFALEDELTEQESL

Gene
trh
Protein
Pro-thyrotropin-releasing hormone
Organism
Danio rerio
Length
199 amino acids
Function
Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
Similarity
Belongs to the TRH family.
Mass
22.739 kDa
Sequence
MRAVCVFVLACVAVSGAPGVRGQDGPAEEELFQRAEDLLLRSILTQMEEQNSENDQPEWMEKRQHPGKRQHPGKREEDLEPEVEMERWRRQHPGKRAPLDLGMLEDPTALSELSKRQHPGKRYLMLLHKRQHPGRRELQEADGDSAELEKRQHPGKRRCEGWADAGCGLLELLDTSGAPEKRQHPGRRAELEDELPGLE

Gene
trh
Protein
Pro-thyrotropin-releasing hormone
Organism
Cyprinus carpio
Length
187 amino acids
Function
Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
Similarity
Belongs to the TRH family.
Mass
21.286 kDa
Sequence
MRAACVILLASLTVSVSPGGQAQALPGEGDPSLDELLQLLRSMLTQMEDENHANGEQTEWLEKRQHPGKREEDGGRLRRQHPGKRLSLEQVMLEEPSEQSELSKRQHPGKRYLMLLHKRQHPGRRELQEASLAKRQHPGKRLCEDWSETGCDPASVLLELLDRSGAEEKRQHPGKRLELEDDLTEQE

Gene
TRH
Protein
Thyrotropin-releasing hormone
Organism
Sus scrofa
Length
3 amino acids
Function
Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
Similarity
Belongs to the TRH family.
Mass
0.38 kDa
Sequence
QHP

Gene
TRH
Protein
Thyrotropin-releasing hormone
Organism
Ovis aries
Length
3 amino acids
Function
Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
Similarity
Belongs to the TRH family.
Mass
0.38 kDa
Sequence
QHP