tnpo

Transportin

931 amino acids

Functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC). Mediates docking of the substrate-importin complex to distinct nucleoporins (By similarity).

Belongs to the importin beta family. Importin beta-2 subfamily.

104.796 kDa

MSEWVPNQDGLKQLVYVLNLSNSTSREVHDQIREELDKFHSVPDYNNYLTLIFKSNELQPHIRSVAGLVLKTNIKQYFEKMPREVQNYIKREILPVLSDPDASVRHTVGNIITNLIKKSCFSEWPELLPALNLALDSNSQDLIEGSLYTLSLLCEDSTKKLDSDDSGRALNQLIPKLIMFFKCNNADFRKKALVSISYFIISMPGALLINMEAFLKGIFSMSEDPSEAVRTNVCKTLVTLVETKIEFLLPYIKDVIQYMLHATKDKSEEVALEACEFWTAISQAEGCRDLLRDYLPVLVPILLNGMVYTEQDYEYLDQGDDSMTPDRPQDIKPFIASTKSHGSGSSGGGQDTGFVNPDNNNNSNNNNSSNNNSSNNNNNNNNEDDEEYNDDDDDDDDDGFEDEAWTIRKSSAFAIDVLSGIFPDAEYLSVTLPLIEQRMNEQNPWPVRESAILALGAIADGSKNGLAPHLSKVIPYLINTLNDPKPLVRSITCWTLSRYSYWIAQADGRDYLHPLVVNLLNRIVDNNKKVQEAACSAFATLEEEADLLLIPYLQMILVTFVNAFGKYQAKNLLILYDAISTLAKVVGNELNKPELINILVPPLLQKFNALDDSNKNLLPLLGCLNQVCSSIGAGLQNLISLFFNRSIKLIEGSLQAHYKYNNQDQKGSSSSSDQDFIVAALDLLQGLSEGIGTSIESLIPNSNLPHLLLQCMNLRGSDVLQSSFALLGDMSKFCLIHFKQYIPDYLNILTNNLYPEYLSVCNNASWAIGEIAIRMPDEVKPFVVAIRDRLISNINKVNLNRGVLENTAVTIGRLGIVSPADISPFVDKFIQCWCMAIRRKTDDIEKDSAFRGMWLIINNNPNGALRHLVYICDAVASWDKMQPDLYEAYFKLLHMYKTSMGGVWAQFYNQFPEQLREILNEKFKLNQDISQ