Protein
Sensor histidine kinase TmoS
Organism
Pseudomonas mendocina
Function
Member of the two-component regulatory system TmoS/TmoT involved in the regulation of toluene degradation. Probably phosphorylates TmoT via a four-step phosphorelay in response to toluene. Can also be induced by benzene and ethylbenzene.
Sequence
MSSLDKRKTQNRSKKNSYSICLKEKASAELKREELARIIFDGLYEFVGLLDAQGNVLEVNQAALNGAGVTLEEIRGKPFWKARWWQISKESVANQKRLVEAASSGEFVRCDIEILGKSGGREVIAVDFSLLPIRDEQENIVFLLAEGRNITDKKKAEAMLALKNHELEQLVERIRKLDNAKSDFFAKVSHELRTPLSLILGPLETIMEAESGRGSPYWKKFEVIQRNAMTLLKQVNTLLDLAKMDAQQMGLSYRRADLSQLTRVISSNFDGIAQQKSITLDAELPPHLIAEVDCEKYERIILNLLSNAFKFTPDGGLIRCHLSLSQPAHALITVSDSGPGIPQNLRKEIFERFHQLNQEGQQANQGTGLGLSIVKEFVELHHGTISVSDAPGGGALFQVKLPLNAPEGAYVANNAMSRSDNPQTVNPDEYLLPIPTAGSGAELPQFQSDQPRVLIVEDNPDMRCFIRDCLSTDYQVYVAPDGAKALELMCSAPPDLLITDLMMPVMSGDTLVHKVREKNEFAHIPIMVLSAKPDEKLRVKLLSESVQDYLLKPFSAHELRARVSNLISMKIAGDALRKELSDQSNDIALLTHRLIKSRHRLQQSNIALTASEARWKAVYENSAAGIVLTDTENRILNANPAFQRITGYTEKDLAQLSMEQLTPPNERTQMKQRLARLLQSGGAEYSVECSYLCKNGSTIWANASVSLMSPRVDEPQVILQIIDDITEKKQAQETLNQLQQELVQVSRSATMGEFAAYIAHEINQPLSAIMTNANAGTRWIGNEPPNIMEAKEALARIIRDSDRAADIIRMVRSFLKRQGPVLKPIDLKALVADTTLILKAPSQSNGVSLNVIAGDTLPAIMGDAVQIQQLVINLAMNSIEAMSQVGCETRQLALSFSSNASNDALIICVKDTGPGIPEDQIGQLFNAFYTTKKEGLGMGLAICLTIAEVHNGKIWAESPPAGGACFFVSIPVS