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tmem178a

Gene
tmem178a
Protein
Transmembrane protein 178A
Organism
Xenopus laevis
Length
304 amino acids
Function
May act as a negative regulator of osteoclast differentiation.
Similarity
Belongs to the TMEM178 family.
Mass
34.065 kDa
Sequence
MESRGLVTAVSLTLSICSLLLLVTAIFTDHWYETDTRKHKEMCDSQGNSDPTEQKNRLMPLYQLPFRGDPSNTRRLGLLSPAPAGGVREPEDLLENWRSLLGLGVLESDCGRPLFSTYSGLWRKCYIMGIDKDIDSLIIKGIAQKCTAIKYHFSHPIRLRNIPFNLTRAIQQDEWHLLHLRRITAGFLGMAAAVLLCGCIVAAISFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASVAYELNRQPKFIYGLPSDVEHGYSWSLFCAWCSLGLIVAAGCLCTAYPFISRTKILHLKFARDSCV
Protein
Transmembrane protein 178A: tmem178a

Gene
tmem178a
Protein
Transmembrane protein 178A
Organism
Danio rerio
Length
301 amino acids
Function
May act as a negative regulator of osteoclast differentiation.
Similarity
Belongs to the TMEM178 family.
Mass
33.992 kDa
Sequence
MEKRALVTAISLSMSLLALMLLVTAIFTDHWYETDTRRHKENCDQYGSESNDQKNREMPIYHLPLVDSGNAKRNLALMKPIHVGSREEELLENWRAILGMGILETECGRPLFSTYSGLWRKCYFQGMDRDIDKLILKGIAERCTSVKYHFSQPIRLRNIPLNLTRTIQQDEWHLLHLRRITAGFLGMAAAVMLCGSIVAAVGFFWEESLTQHVSGLLFLMAGIFCTISLCTYAASVSYDLSRNPPFIYGLPSDVDHGYGWSIFCAWVSLGLTVASGCICTTYPFLSRTKALRSKTARESSV
Protein
Transmembrane protein 178A: tmem178a

Gene
TMEM178A
Protein
Transmembrane protein 178A
Organism
Homo sapiens
Length
297 amino acids
Function
Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1.
Similarity
Belongs to the TMEM178 family.
Mass
33.019 kDa
Sequence
MEPRALVTALSLGLSLCSLGLLVTAIFTDHWYETDPRRHKESCERSRAGADPPDQKNRLMPLSHLPLRDSPPLGRRLLPGGPGRADPESWRSLLGLGGLDAECGRPLFATYSGLWRKCYFLGIDRDIDTLILKGIAQRCTAIKYHFSQPIRLRNIPFNLTKTIQQDEWHLLHLRRITAGFLGMAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAQLKSGRDSTV
Protein
Transmembrane protein 178A: TMEM178A

Gene
Tmem178a
Protein
Transmembrane protein 178A
Organism
Mus musculus
Length
297 amino acids
Function
Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1 (PubMed:26644563).
Similarity
Belongs to the TMEM178 family.
Mass
33.082 kDa
Sequence
MEPRALVTALSLGLSLCSLGLLVTAIFTDHWYETDPRRHKESCERSRAGADPPDQKNRLMPLSHLPLRDSPPLGRRLLPGGPGRSDPESWRSLLGLGGLDAECGRPLFATYSGLWRKCYFLGIDRDIDTLILKGIAQRCTAIKYHFSQPIRLRNIPFNLTKTIQQDEWHLLHLRRITAGFLGMAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASVSYDLNRVPKLIYSLPHDVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAHLKSGRDSTV
Protein
Transmembrane protein 178A: Tmem178a

Gene
Tmem178a
Protein
Transmembrane protein 178A
Organism
Rattus norvegicus
Length
297 amino acids
Function
Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1.
Similarity
Belongs to the TMEM178 family.
Mass
33.08 kDa
Sequence
MEPRALVTALSLGLSLCSLGLLVTAIFTDHWYETDPRRHKESCERSRAGADPPDQKNRLMPLSHLPLRDSPPLGRRLLPGGPGRSDPESWRSLLGLGGLDAECGRPLFATYSGLWRKCYFLGIDRDIDTLILKGIAQRCTAVKYHFSQPIRLRNIPFNLTKIIQQDEWHLLHLRRITAGFLGMAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASVSYDLNRVPKLIYSLPHDVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAHLKSGRDSTV
Protein
Transmembrane protein 178A: Tmem178a