tkrA

Probable 2-ketogluconate reductase

334 amino acids

Catalyzes the NADPH-dependent reduction of 2,5-diketo-D-gluconate (25DKG) to 5-keto-D-gluconate (5KDG), 2-keto-D-gluconate (2KDG) to D-gluconate, and 2-keto-L-gulonate (2KLG) to L-idonate (IA).

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

37.433 kDa

MTSIKNNNENKHIVVYRKIHQSLIEKLENQGYKVTQFEPINSNNIQEFYEAIKTANGLIGSVFKIDENVLSKAPFLECVSAISVGYDNYDLVVLNDRKIPLMHTPNVLNDSMADIMMGLMITVARKLAYCDKRMRNGEWNGPLDKSWFGLEVHHKKVGIIGMGRIGEVLAKRCRMGFDMEVAYYSRSRHLKVEELYDAKHQDLDTILSTSDFICVVLPGSQETKHFFSFGQFSKMKNSAIFINAGRGMTVDEVALIDALETGKIAGAGLDVFEKEPLNKDSKLLTLDNIVLLPHIGTSTIETQHIMSECAVNNLISALNGNLEKNCVNASIIKK

tkrA

Glyoxylate/hydroxypyruvate reductase B

324 amino acids

Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.

35.396 kDa

MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD

tkrA

Glyoxylate/hydroxypyruvate reductase B

323 amino acids

Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.

35.336 kDa

MKPEVLLYKSLPDDLRARLDEHFTVTAINGLSPETIAEHGGAGARRRHDRLQQHGGSSAAGENAKLRAASTISVGYDNFDVEALNQRGIVLIDTPTVLTETVADTMMALVLSSARRVVEVAERVKAGEWRRSIGPDWFGIDVHHKKMGILGMGRIGLALAQRAHHGFGMPILYNARKHHEEAESRFNAQYCDLDTLLRESDFLCISLPLTEQTHHMIGREQLAKMKPSAILINAGRGPVVDEQALIAALKDKTIHAAGLDVFEQEPLPVDSELLTLPNVVALPHIGSATHETRYGMARDAVDNLIAALAGKVEKNCVNPQVLR