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timm22

Gene
TIMM22
Protein
Mitochondrial import inner membrane translocase subunit Tim22
Organism
Homo sapiens
Length
194 amino acids
Function
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
Similarity
Belongs to the Tim17/Tim22/Tim23 family.
Mass
20.031 kDa
Sequence
MAAAAPNAGGSAPETAGSAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEEQKMIEKAMESCAFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNFAIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKAGAIGCGGFAAFSAAIDYYLR

Gene
Timm22
Protein
Mitochondrial import inner membrane translocase subunit Tim22
Organism
Mus musculus
Length
194 amino acids
Function
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
Similarity
Belongs to the Tim17/Tim22/Tim23 family.
Mass
20.114 kDa
Sequence
MAATAPKAGGSAPEAAGSAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEEQKMIERAMESCAFKAVLACVGGFVLGGAFGIFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNFAIVGAMFSCTECLVESYRGKSDWKNSVISGCITGGAIGFRAGVKAGAIGCGGFAAFSAAIDYYLR

Gene
TIMM22
Protein
Mitochondrial import inner membrane translocase subunit Tim22
Organism
Bos taurus
Length
194 amino acids
Function
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
Similarity
Belongs to the Tim17/Tim22/Tim23 family.
Mass
20.156 kDa
Sequence
MAATAPKAGGSAPEAAASAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEEQKMIERAMESCAFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAREVLKDMGQRGMSYAKNFAIVGAMFSCTECLVESYRGKSDWKNSVISGCITGGAIGFRAGLKAGVIGCGGFAAFSAAIDYYLR

Gene
Timm22
Protein
Mitochondrial import inner membrane translocase subunit Tim22
Organism
Rattus norvegicus
Length
192 amino acids
Function
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
Similarity
Belongs to the Tim17/Tim22/Tim23 family.
Mass
19.918 kDa
Sequence
MAAAKAGASAPEAAGSAEAPLQYSLLLQHLVGDKRQPRLLEPGSLGGIPSPAKSEEQKMIERAMESCAFKAVLACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAREVLKDMGQRGMSYAKNFAIVGAMFSCTECLVESYRGKSDWKNSVISGCITGGAIGFRAGVKAGAIGCGGFAAFSAAIDYYLR

Gene
timm22
Protein
Mitochondrial import inner membrane translocase subunit Tim22
Organism
Xenopus tropicalis
Length
186 amino acids
Function
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
Similarity
Belongs to the Tim17/Tim22/Tim23 family.
Mass
19.472 kDa
Sequence
MGGSVSPPGTGEGTLQYSLIMEHLVGDKRRPKEVIPGGLGGIPTPIKSEEQKMMERVMESCGFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNFAIVGAMFSCTECLVESYRGKSDWKNSVISGCITGGAIGFRAGLKAGALGCGGFAAFSAVIDYYLR

Gene
timm22
Protein
Mitochondrial import inner membrane translocase subunit Tim22
Organism
Xenopus laevis
Length
184 amino acids
Function
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
Similarity
Belongs to the Tim17/Tim22/Tim23 family.
Mass
19.389 kDa
Sequence
MGSNVTPPGDGTLQYSLIMQHLVGDKRRPVELIPGGLGGIPTPIKPEEQKMMERVMESCGFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPLRTPTAKEVLRDMGQRGMSYAKNFAIVGAMFSCTECLVESYRGKSDWKNSVMSGCITGGAIGFRAGLKAGVLGCGGFAAFSAVIDYYLR

Gene
timm22
Protein
Mitochondrial import inner membrane translocase subunit tim22
Organism
Dictyostelium discoideum
Length
179 amino acids
Function
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
Similarity
Belongs to the Tim17/Tim22/Tim23 family.
Mass
19.475 kDa
Sequence
MANISDEELKKILSDNAHKFMFAENGVRDFLPNIKNIAPYNEMQYNLMDNCIVHGVRGMVMGGAFGFLFGALFTPNSGFTPEPTTPTPLYRQVIDGFKEQGRSGLRSAKSLSIITLVYTGTECAIEKARGRTDKLNPIYAGCTTGAVFAGRAGPMAAVGGCVGFAVFGMIMDHFMVFFF