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tgtA

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
Length
674 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
77.221 kDa
Sequence
MVDIIVDFEIKYKDAMARVGKFKTPHGTVTTPALMPVVHPGKQTLDVKKLGAQIVITNSYIIYKNEELKKKALEEGVHSLIDFPNTIETDSGSFQLSVYGDIDITNEEVIKFQEAIKTDIGTSLDIPTAPYVKREEAENDLEITIERAKEAANVKSDLLLNSVVQGSTFPDLREKCAKEISKYDADIYPIGAVVPLMEMYRYADLVDAVMYSMRGLPENKPRHLMGAGHPMVFALATAMGCDLFDSAAYILYANKDRFMMPDGTLRLEDLIEMPCSCRVCCEYTVDELKQMDQKKRAKLIAEHNLHISFAEIRRIRQAIVDGELMKLVELRCRSHPFLLDGLRRLMEYKEDMERLNPSSKKSAFFYTGYESLARSEVPKHLKQLENIKPKNKNLVILPHTRKPYTKYVNREYIKKYTPKIPTYYSNTTNTDYSNSDVVVADIPFGIIPLGLDEFYPLAQNESPSIHDLDSKRFIRDIINNYSKKYDNVLIHRKVIEKFDITNFNLIEDELQLPEAKISDFNRLNDIADYQFGCGAGNALFGGDEDKITIEKSRKTKKIRHVFEDNENIVNMRANDGFLILSDLGAKRLHKFLEYPHNRVVVSEDSEPFALKGKSVFNKFVLDCDENIRRNDEVLIVNKDDKLLAFGKALLSSYEIKDFNTGQAIKTRKWKKEIE

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)
Length
659 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
74.78 kDa
Sequence
MFEIKAKDNRGRVGVLKTNSGDVKTPNLMPVIHPRKQTIDVKKYGADIVITNAYLIYKDEDLKKKAAEIGLHKLINFDGPIMTDSGSFQLSVYGDVDITNKEVIEFQELIKTDIGTSLDIPTAPFVTREKAEADLEVTLERAKEAVDYRNSQNMEMKLNSVVQGSTFPDLRRKCADELTKLDADLYPIGAVVPLMESYHYKELVDVVMNSVAHLPDSKPRHLMGAGHPMIFALAVAMGCDLFDSAAYILYAEDDRLLSVRGTYKLENLQEMPCSCEVCCNYTPDDLRAMPKEKRRDLIAQHNLNVSFAELRLIRQAIYEGSLMELVEERCRAHPNLLEALRQLGNYSKDLEKYDPRSKKSAFFYTGSESLYRSEVLRHIQKLRAMPRKRDLVILPPSRKPYSKYVSSKLGNFYVYGSEQELDLNNTDFMVLDIPFGLIPLEIDEIYPLSQNESPRTWDVSSLEFIEDFISEFVEYYDQVLIHSNVIKKLDIGLYNIHSQSDEIRYAKDDLKKVKAIADYQFGVGAGDALFAGNIKIEKSKKTGKIRHIYDGKTLIVNMRASDSFLILSKEGAKRLHAATQYPKNRVVVNKDSEPFSLEGKSVFAKFVVECDEDIRAKDEVLIVNEEDKLLAYGKALLGACEINDFQTGQAIKTRKGMKK

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
655 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. Can also utilize guanine as substrate.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
76.076 kDa
Sequence
MTFEIKHRDAMGRIGILNINGKKIETPTIMPVIHPNPKKQIVSMDLINKLADVIITNSYITYKTKHLREIAEEKGIHKLIGFDKVIVTDSGSFQLGVYGDVEVEPMEIIEFQERIGVDVGTILDIPTPPDVDRERAEKELEETLKRAKASIELKEERGFKLLLNGTVQGSTYLDLRQKSAKEMAKLGFDIYPIGAVVPLMEQYRYRDVAEIIINSKMYLPTNKPVHLFGCGHPMFFALAVALGCDLFDSAAYALYAKDDRYLTERGTLHLEEIKDLKAFPCSCPVCSSYTPKELASLNKKERERLLAEHNLYVTFEEINRIKQAIRDGSLWELVEERVRCHPKLLEAYRVVRKYIDYIEKFDPVTKKSAFFYTGIESMFRPEVLRHKKRLKRLRYEKVYITTVSSSIEKPYHEHLNVVETDVDILIKDPVFGFIPYYIDTVYPLSQHEIPELFDYEKEINKRFVDEFIDWLKKKIGEDNILDIMTYNYYINYFSANKKINADALRIRKMLQYQYGFDIIDDELMNKIKVVRSKTTGRLRQVLDENGEILFSVRSNDNLLIPSEKGAKLLWKKIPFPKYRVVVNKEAEEFAREGRNVFAKFVIDCDEELRPYEEVLVVNEDDELLAYGTTILNGIELREFNYGLAVKVRGGLKINK

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Length
653 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
73.266 kDa
Sequence
MTLWEDFMFEIKSKDGLGRTGILKTEHGTVRTPALMPVIHPGKQTIDVKGPGAEIVITNAYIIYRNPELRERALSDGVHRLIDFDGPIMTDSGSFQLSEYGDIEVENPEIIRFQDEIGTDIGTSLDIPTPPGVSHRRAIEEVEVTLERARESIEYRERMMLNAVVQGSTHPDLRRYCASRLAELPVELHPIGAVVPLMESYRYRELVDAVLSSVSELPPSRPRHLMGAGHPMLFALAVSMGCDLFDSAAYILYAEDDRLLSTEGTYKLENLQEMPCSCSVCTDYTPSELMGMDREERRNLIAEHNLHVSFAEIRKVRQAIHDGNLMELVEERCRAHPRLLEGYRRMSEYLDLIEKFEPRSKRSAFFYTGPESLGRVEVHRHLKRVKEHLGERLALVAPSRRPYSSSLPARIGGFSSLRPQSGGPWRVVVVDLPFGIIPLELDQVYPLAQSDAPGIMDLDGEEFLRGLVRDLMDGDAIVDDALCSELGIELPYKYMGEVETTVDDLDRVRMVADYQFGMGAGELLFTDDVRIERSRNTGKIRHIYAGDELICTMRASDGLLVLGAEGAVRLHKGTDYPAWRVAVNEESEPFARKGKSVFAKFIIDCDNNIRANDEVLIVNADDELLATGKALLCAEEMMDLNHGQAVKTRKGGF

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)
Length
652 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
75.131 kDa
Sequence
MFEIKHRDAMGRIGKLKINGKIIETPTIMPVVHPNPKKQTVSIEKIEKLASVIITNSYIINTNPELKKIAEEKGIHNLIGFDKVIVTDSGSFQLSVYGEITVEPEEIIEFQEKIGVDVGTILDIPTAPYVQREQAEEELKETLRRAELSVKLRDEKNYKLLLNGTIQGSTYMDLRQESAKKMKELDFDIYPIGAVVPLMENYDYAQVIEIILNSKKELPTNKPVHLFGCGHPMMFALSVALGCDLFDSAAYALYAKDGRYLTESGTLHLEDLKDLEKFPCSCPVCIEYTPKELAKMEKRKRTELLAEHNLYITFEEINRIKQAIKDGNLWELVEERCRAHPKLLEAYRKALEYNEFIEEFDPITKKSAFFYGGYESLYRPEIIRHKKRLERIKSDNIYITTISNDINRPYSENTNMMDSDALVLIKDDLFGLVPLSIDTVYPLSQCDNPKLYCYEKIHNNEFVEEFKQNNKDKIMDITSYNYYINHYTSNANKNKVGSDAIRINNMIQYQYGFKLNDEELKKLIIKRSKKTNRIRNVLIPTDGNNKEVLFTLRSNDNLLIPAKEGAKLIHEKLPFPKYRVVIDSEVEEFARDGKSVFSKFVINCDKELRPYEEVIIVNENDELLAYGTTLLNGKELGEFNYGAAVSVRSGFK

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
Length
649 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
74.505 kDa
Sequence
MFEIKARDAMGRLGVITINGKKIETPTIMPVIHPNPKKQTVSMDLINKLADVVITNSYITYTTPELREIAETKGIHELIDFKNVVVTDSGSFQLSVYGDVNVGPMEIIDFQEKIGVDVGTILDIPTGPDVSREKAESDLLETFKRAKDSIKRRKEMGYKLALNGTIQGSKYLDLRQKSAEVMGKMDFDIYPIGAVVPLMEDYRYREVAEVILNSKMHLPTNKPVHLFGCGHPMLFALSVALGCDLFDSAAYALYAKNGRYLTAEGTLHLEDMKDLKSFPCTCKVCSEYTPKQLFNLEEKEKTRLLAEHNLYVTFEEIDRIKNAIKEGNLWELVEERCRSHPKLLNGLRVISKYMDFIEKHDPVSKKSGFFYTGYESMDRPEIYRHKQRLERIQYDKIYVTSVSENTSKPYHENLSNVPCDVDVLIKDSVFGLVPLNIDTMYPLAQNEVPDLYDFEKKYNNEFVSEFREKHTEKILDISTYNYYINHYGKKKDCDKINPDIFRIGKMLEYQYGAKILDDELMGKVKSRRSKNTGRIRNLLLEKEVLFTLRANDNFLIPAKYGAELLHEKLEFPNYRIVIDSSVEEFARAGKSVYSKFVKDCDHELRPFEEVLIVNSDDDLLAYGTTILNGQELMEFDYGVAATLRGGIKK

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanococcus maripaludis (strain C6 / ATCC BAA-1332)
Length
649 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
74.445 kDa
Sequence
MFEIKARDAMGRLGVITINGKKIETPTIMPVIHPNPKKQTVSMDLINKMADVVITNSYITYTTPELREIAETKGIHELIDFKNVVVTDSGSFQLSVYGDVNVGPMEIIDFQEKIGVDVGTILDIPTGPDVSREKAESDLLETFKRAEDSIKRRKEMGYKLALNGTIQGSKYLDLRQKSADVMGKMDFDIYPIGAVVPLMEDYRYREVAEVILNSKMHLPTNKPVHLFGCGHPMLFALSVALGCDLFDSAAYALYAKNGRYLTADGTLHLEDMKDLKNFPCTCKVCSEYTPKQLFNLEEKEKTRLLAEHNLYVTFEEIDRIKNAIKEGNLWELVEERCRSHPKLLNGLRVISKYMDFIEKHDPVSKKSGFFYTGYESMNRPEIYRHKQRLERIQYDKIYVTTVSENTSKPYHENLDNVPCDVDVLIKDSVFGLVPLNIDTMYPLAQNEVPDLYDFEKKYNNEFVSNFMEKNSEKILDISTYNYYINHYGTKKECDKINPDVFRVGKMLEYQYGAKILDDELMEKVKTRRSKNTGRIRNLLLEKEVLFTLRANDNFLIPAKSGAELLHEKLEFPKYRIVIDSSVEEYARAGKSVYSKFVKDCDPELRPFEEVLIVNSDDELLAYGTTILNGLELMEFDYGVAATLRGGLKK

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanococcus maripaludis (strain C7 / ATCC BAA-1331)
Length
649 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
74.483 kDa
Sequence
MFEIKARDAMGRLGSITINGKKIETPTIMPVIHPNPKKQTVSMDLINKMADVVITNSYITYTTPELREIAETKGIHELIDFKNVVVTDSGSFQLSVYGDVNVGPMEIIDFQEKIGVDVGTILDIPTGPDVSREKAESDLIETFKRAEDSIKRRKEMGYKLALNGTIQGSKYLDLRQKSAEVMGKMDFDIYPIGAVVPLMEDYRYREVAEVILNSKMHLPTNKPVHLFGCGHPMLFALSVALGCDLFDSAAYALYAKNGRYLTADGTLHLEDMKDLKSFPCTCKVCSEYTPKQLYNLEEKEKTRLLAEHNLYVTFEEIDRIKNAIKEGNLWELVEERCRSHPKLLNGLRVISKYMDFIEKHDPVSKKSGFFYTGYESMNRPEIYRHKQRLDRIQYDKIYVTSVSENTSKPYHENLSNVPCDVDVLIKDGVFGLVPLNIDTMYPLAQNEVPDLYDFEKKYNNEFVSEFKEKHSEKILDISTYNYYINHYGKKKECDKINPDVFRVGKMLEYQYGAKILDEELMEKVKTRRSKNTGRIRNLLLEKEVLFTLRANDNFLIPAKSGAELLHEKLEFPKYRIVIDSSVEEYARAGKSVYSKFVKDCDPELRPFEEVLVVNSDDELLAYGTTILNGRELMEFDYGVAVTLRGGLKK

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanococcus maripaludis (strain S2 / LL)
Length
649 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
74.401 kDa
Sequence
MFEIKARDAMGRLGSITINGKKIETPTIMPVIHPNPKKQTVSMDLINKMADVVITNSYITYTTPELREIAETKGIHELIDFKNVVVTDSGSFQLSVYGDVNVGPMEIIDFQEKIGVDVGTILDIPTGPDVSREKAESDLIETFKRAEDSIKRRKEMGYKLALNGTIQGSKYLDLRQKSAEVMGKMDFDIYPIGAVVPLMEDYRYREVAEVILNSKMHLPTNKPVHLFGCGHPMLFALSVALGCDLFDSAAYALYAKNGRYLTADGTLHLKDMKDLKSFPCTCKVCSEYTPKQLYNLEEKEKTRLLAEHNLYVTFEEIDRIKNAIKEGNLWELVEERCRSHPKLLNGLRVISKYMDFIEKHDPVSKKSGFFYTGYESMNRPEIYRHKQRLDRIQYDKIYVTSVSENTSKPYSENLSNVPCDVDVLVKDSVFGLVPLNIDTMYPLAQNEVPDLYDFEKKYNNEFVSEFNEKHAEKILDISTYNYYINHYGKKKECDKINPDIFRIGKMLEYQYGAKILDEELMEKVKSRRSKNTGRIRNLLLEKEVLFTLRANDNFLIPAKSGAELLHEKLEFPKYRIVIDSSVEEFARAGKSVYSKFVKDCDPELRPFEEVLIVNSDDELLAYGTTILNGRELMEFDYGVAATLRGGLKK

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
Length
649 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
74.731 kDa
Sequence
MFEIKARDAMGRLGLIKINGKKIETPTIMPVVHPNPKKQTVSIDLINKLSDVIITNSYITYTTPELREIAENKGIHHLTGFKNVVVTDSGSFQLSVYGNVNVEPMEIIDFQEKIGVDVGTILDIPTAPDVSREKAEKELLETFKRAEDSIQRRNDRNYKLALNGTVQGSTHLDLRRKSAEVMGKMDFEIYPIGAVVPLMEDYRYREVSEIIINSKMHLPTNKPVHLFGCGHPMLFALSVALGCDLFDSAAYALYAKNGRYLTENGTLHLDELKDLKNFPCSCKVCSEYTPKQLQNMKEKERERLLAEHNLYVTFEEIDRIKNAIKDGNLWELVEERCRSHPKLLNGLRVISKYMDFIEKYDPVSKKSGFFYTGYESMARPEIYRHKQRLNRLKFDKIYVTSISEKINTPYSENLNNIPCDVDVLIKDSVFGLVPLNIDTMYPLSQNEIPDLYDFEKNYNNDFISEFLENNAEKVLDISTYNYYISHYNSKKECEKINPDLLRISRMLEYQYGAKIIDNDFEKLSVRRSKTSGRIRNVLLDKEVVFTVRASDNFLIPAKLGAEMLHKKLEFPKYRVIVDKSVEEFARAGKSVYSKFVINCDKELRPFEEVLVVNENDDLLAYGTNLLNSQELMEFDYGVAVNIRGGLKLE

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Length
632 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
71.91 kDa
Sequence
MKIEERDGLARIAKFETPHGPIETPTVLPVINPNIMNITPQEMKPLGLQGIITNSYIILRTPELRERALREGLHSLIGYDGPIMTDSGTFQSYVYGSIEFNNREVVDFQRRIGSDISTILDVFTTPGTPKPEAEKAVIETYNRMLEVNDEEGIIAGPVQGGVYPDLRQKSAELMNSTNAGYHPIGGVVPLLETYDYSTLVDIIINSKINLSFNKPVHLFGGGHPMFFAFSVYLGVDLFDSASYIKYAKDDRLIYPDGTRDLARITELPQWSPLYDRYTVKEIRDLDKERRSLEIARHNLKAIFMEISEIKERIYEEGLAQYVAQKARSHPSLMKAYSRIMSYSNILEKYEDLSKKTAYFFYDSFSTRNPYVSRINRFTESYLSSNKKDTYAFTYRAWNPGYTNSEFVRDVYQKIDCNALISWSGTFVPAELENTYPIEQTVSSGFEPDPDFSRAKDLIAPFRVDMYKGEKFEGEQVRSFNLNKIRMVADYQFGSGVGRMIFRDDVRINVSKTGRIRGILSKEGRQIATMRNDGFFTLTYYGASLIHSQLKPPAMRVTVSKESAEYNAKGYSVFFKFILGSDENIIAKNDVLVVDEDDVLAAVGKAMVSGRELREYTEGIAVKVHEGRDQSEK

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Length
632 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
71.957 kDa
Sequence
MEIRERDGLARIARFDTPHGTIETPTVLPVINPNIMDITPEEMKKYGVHGVITNSYIILRNDRLREEAEKYGVHSLIGYDGPVMTDSGTFQSYVYGSVEFNNRQVVEFQKTIGSDILTILDIFTTPSSSRQEVENAITETYRRMLEVNDAGGMIAGPIQGGIYPDLRKRSAELMNSTNASYLPIGGVVPLLESYEYDKLVDIILNSKLNVSFGKPIHLFGGGHPMFFAFAVYLGVDLFDSASYVKYAKDDRLIYPDGTRDLARIIEIPEWSPLFDKYTVKELKELPKEQRSVELSRHNLKAIFMEISEIRERIYEESMDQYLAQKAKSHPSLLKAYVKVMQYSKMLEKYQDLFKKAAYFFYDSFSTKNTYVARLEKFTSKYLTSKKKETYVFSRKDWLPGYTNLNFVRDVYERTECNALIPWSGIMVPAELENTYPIEQTVSSGLEPDPDVSAISESISPFDIRVYKGESVDSDKIRSFDLEKIRTIADYQFGYGIGKDFFKDDVRIFKSKTGRIRGVFDKGNKLIATLRNDGFFTLTFHGATLLYNVSKSPNLRVFVKNESAEYNAKGYSVFFKFILDADPDIIAKNETLVVNENGELVAVGKATVSGKELREYSDGIAVKIHEGRDQSAK

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)
Length
625 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
72.063 kDa
Sequence
MEILFRENLARIARFKTPHGEIETPTVMPVINPNLNFLDESTLRSYGVQAVITNSYIIKRNQRLNEDALRHGLHSLIKFSGPIMTDSGTFQSHVYGDIEYSNKEIVDFQKAIGSDIITILDVFTEPDESYNSARSKVIETYKRLKEIDFEDKIIAGPVQGSIYPDLRRLSAYLMSDALYLPIGGVVPLLESYRYSDLVKIIFNSKVSSDFSRPVHLFGGGHPMFFAFAVMLGVDLFDSASYIKYAKDNRLLYSEGTRALNDIREFPEWSPIHGKYTPQELLHEESEKRTRMLALHNLKSIFIEINEIKERIYENTLYNYVEEKARSHPALFKAFMSMINYDTSDYSPLSYKSPFFYYDKTSLNHPIIKRIMKFTENYISNSRHTLIISSKYWRPGVKNENVIKNIVECTDFNLLVSWNGIYIPLFLEDSYPVQQLVSSGLNDKKLEEDYLKRLKSINNDIEFYEGEHYDKRLRDYDTEKINTIAMFQFNINERFFDKSNIIKSKSTGHIRNIIEDNNIIATMRNDGYLTLSIKGAYRLLSMKPWPGLRVVVDDESGRFNANGYNVFFKFIKSFDTGIIPGNETLVVSEDDDLYAVGKAAVSGIEMYYYKSGVAVKVHEGVNKKAA

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Korarchaeum cryptofilum (strain OPF8)
Length
590 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
67.149 kDa
Sequence
MGLYFRVRKSDASARLSELKTKSGTLILPEFFPVYNPNKPVITPREMSEMGIKAIITNSYLIYRSPELREAAIERGIHSLLGFDGVVMTDSGAYQIYRYGRVDVTNSEILRFQHSIGSDIGSILDVPMSSEIGREEAESGVERTIRNAEEWASMREELSNTLWVGTPQGSIYRDLVIKCSERIRELDFDYNGVGSIKVALEKYDFVTQVDHFMSIRSILRAGKPFHFWGIGHPSTFAFFAAIGADSFDSASYSLYAEQGRYMTPHGTLLLDEIEEFPCSCPVCSSHDPKEVKAMSKEERTKLLAKHNLYISISEIKKVREAIRGEWLWELVQERSRFHPNLYFALMHLLRRYSSLLEAREPLFKSSGLQCSGPESFLRPEVVRARNRLKYIHYNGKFRRVLYGDVPLGLKYLYPFGQTICPYDEEVQDEPEDDEIITCVLSYQYEFPFPKLPAIMRRSKSTGTLREVSLEGKVIGHFRPNDGAFIPTLDGASLILSHLPYPKGRVVVKGLFSDTVARGTTVFVKFVKEADPSIRPKSEVIVVNESDELLATGKAVLSGVEYHQYHPDHPFIIIRRHVKPRSEEKPPEVDS

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Length
585 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
66.941 kDa
Sequence
MSRGDSMLRFEIKDRDAAGRIGKLEVNGKKIETPAIMPVVNPKQLIVEPKELKRMGFDIIITNSYIIYKDKKLREKALEKGIHRLLDYDGIIEVDSGSFQLMRYGKVEVTNREIVEFQHKIGVDIGTFLDIPTPPDAPREKAEQDLKITLERAKEAESIKQIPMNATVQGSTYLDLRKLAARKLSEMNFEIHPIGAVVPLLESYRFKDVVDIVIASKMGLRPDRPVHLFGAGHPMVFALAVAMGVDLFDSASYALYAKDDRYLTPQGTKRLEELEYFSCSCPVCSKYTPQELREMPKEEREKLLALHNLWVIREEINRVKQAIKEGELWRLVDERARAHPKLYAAYKRLLEYYHYLEEYEPITKKSAFFKISEESLKWPIARRAKERAEKVKAKFPESIPHPIFGEIPKYLSLTYPFAQSESEEDFQIEKPTRENAILYIMAIAEYQFGEGAGEAFRDAEVEIAKTGMPRQVKKNGKRLATVRAEDGLLTLGIEGAKRLHELLPYPVMRVVVNKEAEPFARKGKDVFAKFVEFADPKIRPYDEVLIVNENDELLATGQALLSGREMVLFSSGRAVKTRRGVEEKK

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Length
584 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
66.668 kDa
Sequence
MSRGDKMLKFEVKARDGAGRIGKLEVNGKKIETPAIMPVVNPKQLIVEPKELEKMGFDIIITNSYIIYKDRELREKALEVGIHKLLGYDGIIEVDSGSFQLMRYGNVDVSNREIVEFQHRIGVDIGTFLDIPTPPDAPKEKAMEDLKITLERAREAEEIKEIAMNAAIQGSTYTDLRRYAARRLSSMNFEIHPIGGVVPLLEAYRFREVVDIVISSKMALRPDRPVHLFGAGHPMVFALAVAMGVDLFDSASYALYAKDDRYLTPEGTKRLDELEYFPCSCPVCSRYTPQELREMPKEERARLLAIHNLWVIKEEIERIKQAIREGELWRLVDERARSHPKLYSAYKRLLDHYTFLEEFEPVTKKSAVFKISHESLRWPLVRRARERAERVNSKFGDLVEHPIFGKVTKYLTLTYPFAQSEAEDEFSIEKPTRENAIRYVMAIAEYQFGENASKAFEGAEVELARTGMPRQVKLNGKRLATVRAEDGFLTLGIEGAKRLHKVLEYPRMRVVVSEEAEPFARKGKDVFAKFVLFADPGIRPYDEVLVVNEKDELLATGQALMSGREMIVFQYGRAVKVRRGISGG

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Length
582 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
66.596 kDa
Sequence
MSRGDKMLKFEIKARDGAGRIGKLEVNGKKIETPAIMPVVNPKQMVVEPKELEKMGFEIIITNSYIIYKDEELRRKALELGIHRMLDYNGIIEVDSGSFQLMKYGSIEVSNREIIEFQHRIGVDIGTFLDIPTPPDAPREQAVKELEITLSRAREAEEIKEIPMNATIQGSTYTDLRRYAARRLSSMNFEIHPIGGVVPLLESYRFRDVVDIVISSKMALRPDRPVHLFGAGHPIVFALAVAMGVDLFDSASYALYAKDDRYMTPEGTKRLDELDYFPCSCPVCSKYTPQELREMPKEERTRLLALHNLWVIKEEIKRVKQAIKEGELWRLVDERARSHPKLYSAYKRLLEHYTFLEEFEPITKKSALFKISNESLRWPVVRRAKERAKSINERFGELVEHPIFGRVSRYLSLTYPFAQSEAEDDFKIEKPTKEDAIKYVMAIAEYQFGEGASRAFDDAKVELSKTGMPRQVKVNGKRLATVRADDGLLTLGIEGAKRLHRVLPYPRMRVVVNKEAEPFARKGKDVFAKFVIFADPGIRPYDEVLVVNENDELLATGQALLSGREMIVFQYGRAVKVRKGVE

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Length
580 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
66.206 kDa
Sequence
MVDFRFEVKARDASGRIGKLTVNGKTVETPAIMPVINPKQLIVTPKELKEMGFGMIITNSYIIYKTPELREKALEVGIHKLLDYDGIIEVDSGSFQLMRYGGVEVTNREIVEFQHEIGVDIGTFLDIPTPPDAPREKAEEDLRITLERAKEAEEIKEIAMNAAVQGSTYPDLRTYAARELSRMNFEIHPIGAVVPLMESYRYRDLVDVVIASKVGLRPDRPVHLFGAGHPMIFALAVAMGIDLFDSASYALYAKDDRYMTPEGTKRLEELEYFPCSCPVCSRYTPQELREMPKEERTRLLAIHNLWVIREELNRVKQAIKEGELWRLVDERARSHPKLYAAYKRLLEYREYLEKNEPVTKASAFFKVSEEALRWPIVERARERAERVRSKFPETISHPIFGEIPKYLSLSYPFAQSEGEEDFTVEKPEKGEARKYVMAVAEYQFGEGAGEAFKDAFVELSRKTGMPRQIKAKGKHLATFRAEDGLLTLGIEGAKRLHEVLPFPRMRVVVDEDAEPFARRGKNVFAKFVVDADLNIRPYDEVLVVNRNDELLATGQTLLNGEELKIFQQGLAVKVRRGVEK

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Thermococcus onnurineus (strain NA1)
Length
580 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
66.172 kDa
Sequence
MVEFKFEVKARDAAGRIGKLEVNGKKIETPAIMPVINPKQLTVTPKELKEMGFGIIITNSYIIYKTPELREKALEVGIHRLLDYDGIIEVDSGSFQLMRYGGVDVTNREIVEFQERIGVDIGTFLDIPTPPDAPREKAEEDLRITLERAKEAEEIKGIAMNAAVQGSTYPDLRTYAARKLSEMNFEIHPIGAVVPLMESYRYRDLVDVVIASKQGLRSDRPVHLFGAGHPMIFALAVAMGIDLFDSASYALYAKDDRYLTPEGTKHLSELEYFPCSCPVCSRYTPRELREMPKEERTRLLALHNLWVIREELNRVKQAIKEGELWRLVDERARSHPKLYAAYKRLLEYQDYLEKNEPITKASAFFKVSEESLKWPIVQRAKARAERVKAKFPETINHPIFGEIPKYLSLSYPFAQSEGEEDFTIEKPGKREVRNYVMAVAEYQFGEGTREAFKDAFVELSRKTGMPRQIKAKGKHLATFRAEDGLLTLGIEGAKRLHEILPFPRMRVVVDEDAEPFARKGKNVFAKFVIDADENIRPYDEVLIVNRNDELLATGQTLLNGRELKLFQSGLAVKVRRGVEK

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara)
Length
520 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
57.073 kDa
Sequence
MRDIFERRDGDAAGRIGELSVPRAGTTVETPALLPVVNPHIRTIAPAELESTFGAQILITNGYILYGSDEYRERALADGLHDLFDFSGAIMTDSGSFQLSEYGEISVTNEEILRFQRDIGSDIGTPVDIPTPPEASREQTAADLETTKARLEAAETVDTGEMLVNAPVQGGTYPDLREEAAEHAYGTTLDVFPVGAVVPLMNSYRYGDMIEAILGAKRGLGADAPVHLFGAGHPMMFALAVAAGCDLFDSAAYALYARDDRYLTVAGTDHLDDLEYLPCSCPVCADHTPAELQAEDDTERERLLARHNLHVSFQELRTIKQAIKKGNLLELVERRARGHPAMVDGYRALLEAADQLERDDPVSKGSFFYLSGESARRPEVKRHHDRLSRLSVDGDRVLLSEGGDNSRFDETWRLQPPFGPFPPALSDSYPLTAELPERLDDRAYEAAAKGVRRLVDDHPETEFAVAHWGWPDAALDSLPDGVELLRLGADSDHPERDSAQSDMDGDEPKEDYPPGEDENA

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)
Length
516 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
56.3 kDa
Sequence
MRDHFELRDGDLAGRIGRLSVPRAGVTVETPALLPVVNPNIDTISPARLESEFGAEILITNSYIIKTNDHLREEALDVGLHEMLDFDGAIMTDSGSFQLAEYGEIDTTTEEILQFQRDIGTDIATPVDIPTPPDVAREQAEADLEITRQALADAEAADTGEMLVNAPVQGSTYPDLREEAGRHADATDLDVFPVGAVVPMMNAYRYDDMVDAVAAAKRGLGVDAPVHLFGAGHPMMLALAVALGCDLFDSAAYALYARDGRYLTVRGTEHLEDLDYLPCTCPICTEYSPDDLREKGSKRQEQLLAEHNLHVTFAELRRIKQAIRDGDLMELVEERARSHPAMLDGYRALLAHVDQLEREDPASKGAFFYASNESAHRPEVARHHARMDRLTAEGHVLLTEGGVPSGDDFDATWRVVPPFGPFPRSLSETYPLTAEVPERLDRDAYEQAARGVSRLVEENPDAAFTLAHDDWPESALARVPESVELESLSAVSERLGDEASVGGDDGDDGGSASSAE

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Length
512 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
57.376 kDa
Sequence
MFEIRDVDLAGRIGRIYTQHGVVETPAFFPVIDVYRQEVSVDEVRAAGFGQVITNAYLLWKRFGWEAAEKGVHRILGFPGVVMTDSGAYQILEYGGVELSQGEVVEYQKRLGSDIAVILDIPTGDVGRREAEESVRETIRRALEARVMIEGDERIWVYPVQGGRYFDLVEESARVGGRLGFYRMYGIGSPTVFLERYMYHVVVEAVYRAKKHLPWGRPVHLFGAGHPLIFPYAVALGVDTFDSASYILYAREGRYITEYGVYRIEDLDYLPCSCPVCSRYTPQELREMDRVERTRLLALHNLYVISASMRRVKQAIREGRLWELLEETSRKHPSTARVMARMRRYIDALEKGSARGRGVVRGVRAYGLESLSNPRLSRFSSDAARLVEAMAEKWGGGKAVLKPLDPKPEPGQCESMVGGGEWILFYQPFLGVFPVEACGAYPSLQIDYPQEGLPAEVIGDLASKIASTVSILRGRGFTVRLEYCGKVEWQARAVEALKTAAAGDLPTVEACG

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Length
503 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
58.318 kDa
Sequence
MTVFEVKYEDLAGRIGTLRTRSGTLETPAFFPVINVLKKDEISIDEIRNIGFKNFITNSYILYKNNYIKDDIHKELRSEEMIIMTDSGAYQILEYGEIGITNLQIVNYQLKIKPDIGVILDLPTGNINDYDNAKKTVYETLKRAEEASEIIVKNQDNNIIWVYPIQGGRYLDLVKTSAEGLSKFEHIYNMAALGSPTVLLEKYMYDTVIDMIYTAKSNIKRGIPFHLFGGGLPHIIPFAVALGVDSFDSASYIIYARDNRYITRTRVYKLEDLEYFPCSCPICSKYTPKDLLEMNEKERTKALAIHNLYTILEEFKATKQAIKEGRLFEYLQEKAYSHPAVYSAFKRLMKYKDYLEKFDPRIRGDPKGLFLFDGNSLHRPEIIRHSRFLERYIQKKDKISIYCYDKAISDTAYDFKEKIREKIADRNESDVFIAVPFFGLIPLEISDSYPLSQFEIPNEIDEDVIDDMKTKIISFLRRNNYQKVELINCEKLGLHIDSISTSS

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Length
498 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
57.427 kDa
Sequence
MIGDFEIKDEDLAGRIGILETKHGKLETPAFFPVINPVKNEITIQDILSVGFESIITNAFLIKKYIGKEEDLHSILNYNKILMTDSGAYQILQYGDIDVSNVDIVNYETKLKPDIAVILDIPTGLTEDKKEAEKSVESTISRAKEASKFVELSKDEIIWVHPIQGGMYLDLIEYSARIADMNQDYKMLALGSPTVLMQRYEYAPLIDMIYKSKSNVSRGKPFHLFGGGHPHIFAFAVALGVDTFDSASYILYARDHRYMTRERVYRLEELDYFPCSCPICSRYSPKDVMEMPEEQKVRLIALHNLYVIKEEINYIKQSLKEGRLFEYIQQKAYSHPSTFEAFRRILNYSKYLEKYDPRVKGEVKGVFLFDNSSLHRPEVIRHAYTLSKIKQRSKALVLYCSDSKDNPLKNTEDMKNADVYIVLPFYGCVPYNVFFTYPYFQSEMPSTIDKDVIYDLKNKLKEFLSQRSYETVSIIGCEKILHVDSIRGAPVNLLLNKL

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Length
495 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
56.923 kDa
Sequence
MSFEIIAKDLAGRVGKLYTKSGVIETPALFPVVDPRKQELPSAVIERYFGQIITNAYFVYRLTGGRAVDIKKVLSWNAVLMTDSGAYQILRYGSVEVDPDEILQFQARIGSDIGVILDLPFDYEEPYESALLKVEETIRRAKRASAMLDKLEDMLVVGPIQGGLYLDLLATSAREISKLGFHIFAVGSPTTLLEEYRFDLLLEVILHVKANILREAPLHLFGAGHPLVLPFAVALGVDLFDSASYILYARDDRIMLRDRTLRLEDVKTDYLPCSTKLCHKPVKELREMPHEERIQLIAEHNLAILREELLEIKQRIHEGTLWEYLEIKARAHPTLYRFLRSLGRYKRLIEEYDPETHPETHGLFFYQDTAESRPEPHRHWSRTANLYTPSKVAIVIRAGEKPYNKSWEYRYLKSLVGDRAHVLFYDPVFGLVPEEVAEIYPLSQNEAEGESEAARAFAYEWLNNYDVILLYRVDLPMLSKKVIPLRSLDDVLHYI

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
Length
491 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
53.507 kDa
Sequence
MRDVFEVGAQDGLARIGELDVPRAGVTVETPTLMPVVNPNLITVEPSRFVDEFGAELLITNSYIINSDDDLRERALDEGLHEMLGFDGAIMTDSGSFQLAEYGEIDTDTEAILRFQHDIGSDIGTPVDIPTPPDADREQAAAELETTQQRLELAETVDVGDMLVNAPVQGATQPDLREQAGAHAYGTALDLFPVGAVVPLMNQYRYDDMTEAVLAAKRGLGRDAPVHLFGAGHPMMFALAAALGCDLFDSAAYAIYARDDRYLTVSGTEHLDDLHYFPCDCPVCAEHSPQAVRGMAAGDRERLLAEHNLHVSFGEIRRVKQAIKSGTLMELVAARAHAHPSTLDGYRALLDHSDQLEASDPASKDAFFYTGAGSARRPEVHRHHQRLDRLDVDGDDVLLTEGDSNHRYDESWNVLPPFGPYPSALATTYPLTAETPARMDRAGYEAAAEGVCRLAEANPDTAFTLAHDDWPESALEAVPQRVSLYNAVRGE

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Length
491 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
56.987 kDa
Sequence
MVGEFEIKDEDLAGRIGIIETKSGKLETPVFFPVINPFKSEISIKDIENLGFKNLITNAYLIKKITNTKIQDIHSFLQFNGVIMTDSGAYQILQYGNIEVTNREIVEYERDINTDIAVYLDLPTGDTNSRDEAINSVKITLERAKEIEDIVKNDSERIWVHPIQGGRFLDLVEYSAIEADKNEAFKMLALGSPTVVMEKYDYSLLIDMVFIAKSNVSRGKPFHLFGGGLPHIMPLVIALGVDSFDSASYILYARDNRYITRSRVYRLEELEYFPCSCPICLKYTPKELLELPKEERTKLLALHNLYVIKEELNAIKQAIREGRLFEYIQEKAYSHPAVYSAFKKILKYKDYLEKYDPRVKGNIRGIFLFDLKSLNRPEIVRHYNFLDRINKNNDKAIIICEKRENILKKVKNNENVDIYLFNPFYGLIPINLIEVYPYFQTEYPEEIDEDVLRYIESKIVEFVRSKGYTKIDFIGCEKYLSHINSIGAFFS

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
Length
490 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
53.92 kDa
Sequence
MTNFEVRQYDAAGRLGELTVPRAGVTVETPTILPVVNPHVQTVAPATLASEFGAEILITNSYILHGSDDLREPVLEQGLHDLLGFDGAIMTDSGSFQLAEYGDIDVTTEEILEFQHEIGSDIGTPVDIPTPPDVDRERATEELKTTQERLEHAATVDTGEMLVSAPVQGATYPDLRERAAADAVSTGLDVFPLGAVVPLMNEYRYADLADVVAACKRGLGEVGPVHLFGAGHPMMFAMAAALGCDLFDSAAYALYARDDRYLTVQGTELLDELSYFPCHCPVCTDHTPAELDAMDADAREELLARHNLHVTYGEIRTVKQAIRSGNLMELVDSRARGHPEMLDGYRALLDHSEQLERTDPVSKDAFFYTSTESARRPEVRRHQDRLERLPVEGEEVLLTEGSSSAQYDESWGVLPPFGPYPRELADTYPLTAETPDRTDRAAYEAAATGVRRLVELHPDVSFTLVHDDWPATALDRVPEGVRLRDLHARD

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Length
490 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
54.936 kDa
Sequence
MSAIFEILDKDAGGRIGKLRTPHGIVETPTVMPVINPNIQLISPKEMKSFGAEILITNSYIIYRKEELRTVALEKGLHGLLGFDGPIMTDSGSFQLSVYGSVEVTNEEILGFQQKIGSDIIVPLDIPTPPDVHFRRAEEELAVTAERLEAARKFIQGEQLLAGPVQGSTYPELREKAASRLRDLNFEVYPLGAVVPLMEAYRYAELVDVIAASKKGLSPTSPVHLFGAGHPMMFALAVSLGCDLFDSAAYALYAKDGRYITANGTYHLEKLNYLPCSCPVCSKYTADELRKAKNKEELLGKHNLYATFAEIRLIKQSIKDGKLLELVEQRCRAHPKLLDGLKRLYTHSAWLEQFDPATKGTYFYCGPESSFRPEVLRFEKRLDRFSLEGSAIIRTAPVKGEKDYDRVLTFKAPFGSFPAEMEEVYPFNAEVPKFPDYETLSTALSNTLKLMELNPGAEFTFICEKEFEHPLIEEIGKKAKLVYRAAWKKE

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Length
490 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
55.093 kDa
Sequence
MSAIFEILDKDAGGRIGRLRTPHGTVETPTVMPVINPNIQLIPPKEMRNFGAEILITNSYIIYRKEELKSVALEKGLHGLLGFDGPIMTDSGSFQLSVYGSVEVTNEEILGFQQKIGSDIIVPLDIPTPPDVHYRRAEEELAITAERLEAARKFIQSEQLLAGPVQGSTYPELREKAASHLKDLNFEVYPLGAVVPLMEAYRYAELVDVIAASKKGLSPASPVHLFGAGHPMMFALAVAMGCDLFDSAAYALYAKDGRYITVNGTYHVEKLNYLPCSCPVCSKYTAEELKKADNREELLGKHNLYATFAEIRLIKQCIKDGKLLELVEQRCRAHPKLLDGLKKLYTHSSWLEQLDPATKGTFFYCGPESSSRPEILRFGKRLDRFSLQGSVIIRTGSVKGEKDYDQILTFKAPFGAFPVEMEEVYPFNAEVPKFPDYESLNTALSNTLKLIDLNPEAEFTFICEEEFKHPLIEEIRKRAKLVYRKDWKKE

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Length
490 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
55.032 kDa
Sequence
MSAIFEILDKDAGGRIGKLRTPHGVVETPTVMPVINPNIQLISPKEMRSFGAEILITNSYIIYRKEELRTVALEKGLHELLGFDGPIMTDSGSFQLSVYGSVEVTNEEILGFQEKIGSDIIVPLDIPTPPDVHFRRAEEELATTAERLEAARKFIQSKQLLAGPVQGSTYPELREKAASHLKDLNFEVYPLGAVVPLMESYRYAELVDVIAASKKGLSPTSPVHLFGAGHPMMFALAVALGCDLFDSAAYALYAKDGRYITSNGTYHLEKLNYLPCSCPVCSRYTAEELRKAKNKEELLGRHNLYATFAEIRLIKQSIKDGKLLELVEQRCRAHPKLLDGLKRLYTHSAWLEQFDPATKGTYFYCGPESASRPEVLRFGKRLERFSIEGSAIIRTSPVKGEKDYDRILTFKAPFGTFPAEMEEVYPFNAEVPKFPDYEALSTSLSNTIKLMDLNPGAEFTFICEKEFQHPLIEEIGKKAKLVYREAWKKE

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Length
489 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
55.058 kDa
Sequence
MTLSFEILEKDIAGRIGKLSGQGKIVKTPTLLPVINPHLNLIPPKEMQEMGVEAVITNAYIFSRSEEYRERALTDGLAKTLDFDGVIMTDSGSFQLSVYGEVEITNAQTIAFQQAIKSDIIVPLDIPTHPDSPREQVEQELSVTMDRIMEAKDIADHEHHTLAGPVQGGLFPDLREETGRRLSEAGFRFCPIGAVVPLMESYRYAELVKVVMAAKRGLSPAVCVHLFGAGHPSMFALAVAMGCDLFDSAAYALYAKDGRYMTTHGSYHLNELSYLPCPCPVCVGHTAKELNESPDRERLLAMHNLRVSLAEINRVRQAIRDGVLWELVDERCRSHPALLRGYRTLLGYNEELTALDRETKRRFFYRGDESCKRTEVVRYHQMVGRLTAGERTLISFSRHIKKKQTEEYDSVFYFKPPFGPFPAELTETFPIGQSEIPDFDEEMIKTGCIGIARLMETNPDSHFTIRCRPVWKDLITQILPTVEVQDEGS

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Length
481 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
54.819 kDa
Sequence
MQRFEILDKDAMGRICRIETPHGRIETPTILPVINPNIPFIRAEEMKKFGAQAVITNSYIIYRSMREEALEKGVHGILETDMPVMTDSGSYQLMVYGDVEIKNAEIVEFQRHIGSDIIVPLDIPTPPDADYATAESDLRITLEREREAKELLKGAENLLAVPVQGSTHPDLRRFAAGEARKIGGDIYPIGAVVPLMDAYRFRDLARVILEVRSALPVEPIHLFGCGHPMLFAMAVALGCDLFDSAAYALYAKDDRYLTVYGTKKLSELNYFPCKCPVCSNHDPEELRRMEKNERERLIAEHNLYVSFQEIETIKQAIKENSLFELVEKRVRAHPNMLAGWRQVKHYWELLEKADPKMKRKFLYTGIDSLYRPAVRRHVKAIKNVELPEEVLVSTDFGIYANIYLRPVFGPVPAEMLETYPAGHAEIPEEDVVEEEALKAASEALMELMNSHPEKRFKVYVSKVWMKHLQNLPPNGELNVLS

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Length
459 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
51.749 kDa
Sequence
MNVAFEVKDRDVAGRLGRLEVNGRRLKTPALLPVVNPNKPTLDPREISKLGFDGVITNAYIIRKHEHLREQALEEGVHGLLGFDGFVMTDSGSFQLAEYGDVEVSNEEIVRFQAKIGSDVGTILDVPTPPDAPRSRVERDLETTLKRAREAVELDEHPPLALTVQGSTYEDLRRLCAEKLAELPAAVYPVGGVVPLLEEYRFVDVVRVVLAAKSSLPPHRPVHLFGCGHPLAIPLAVAMGCDLFDSASYAIYARSDRYMSILGTLKLEELETFPCSCPACTRHDPDDVREMEPRERTRVLATHNLYELRRVIETTRQAIVSGELWELAESVCRAHPRAWAGMVELARRGGELERWCPAVKRSVFVCDEVSKGRPELRLYRRRLRDRFGELSGRKVVKGISRPYAEIVEWLEPWELAFADEWLGVVPGELSWSYPCHCLVEPSGDDEGEDRRRGEEGRRR

Gene
tgtA
Protein
tRNA-guanine(15) transglycosylase
Organism
Nanoarchaeum equitans (strain Kin4-M)
Length
410 amino acids
Function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Similarity
Belongs to the archaeosine tRNA-ribosyltransferase family.
Mass
47.647 kDa
Sequence
MKIKFEIKYKDAAGKVGKIKLNGKTIETPYLFPVINPFKQELPIKEIKKMGFNAIITNAYILFKRKEEVMEKGIHNFLGFDGIIETDSGAYQLLQYGDIDIENEDIIYFQNEIGVDIGNILDIPSYGKTYEEAKKDLEITLERLKQAIEMANFAINGPIQGDKYLDLRYKALEEVSKLDIDIYAIGGIVPYMNQYKIESLAKIIGPLLLDIPRDRPVHLFGLGHPLIMPLFVALGADLFDSASYSLFAKEERILTPFRTFRLEDLTDSYILDYKASELKGMENKTYIIAKHNLLVLRNEINFIRDLIRQNRLWDYVIIKAHAHPSIYFATKYVLENLYEKLKEHEPITKRVGILYQGELTELRSDLRYAIEQLKKLDKSQINDILDYAWPFGQFEIGEKDKKLFFQRFLK