Tet

DNA N6-methyl adenine demethylase

2860 amino acids

Dioxygenase that specifically demethylates DNA methylated on the 6th position of adenine (N(6)-methyladenosine) DNA. N(6)-methyladenosine (m6A) DNA is present at a relatively high level at the very earliest embryonic stages but at low levels at the late embryonic stages and may act as a regulator of gene expression. Promotes differentiation of early germ cells in ovary.

Belongs to the TET family.

306.7 kDa

MASSILAQSSTGATVDSSNLGATAAAATSVEATVSSLHNTHLNQLSSLSQHYTTPYHHPHSHSHPHHHYQQHYPQQQHLQQQQQQQHHAQQQHQQQQQQQQQQQQQHWDYYARQQQQHQQQQQQQQQPAAATGNTNGNSSNNGNNGNNGNNSNPDGSNTTVPAPLGSSNNSSSNHANAASGGNSGQRHGDANANAISAASAAVGNPGNQQPNNSAGNANSNSNSNSNSNGSYTRPWEMESKDNGPQPPQTQPHLQLKSGFEPFSKLPSFQSQFHGFNEQLLPDGTPMPVPIGAGVPPGSAAAVAAATGSIPPGSVGPNSVAGPVGPTAMSSLQTVAMSPASISVSSPGMMSVGSPLTQLSSLQTSITPPSAGSFPAPPPPNAFAHHHALNPHHHHRGASGYPTPYAELPLYPGFTPLSVKKEPISGGSDFEMLLKKEDFDLSNSGGAGLIHHPLQHGQPHPIPMGMHTPTSYDGNNSNNSYPQAAGGGSGSHTPHTTTTQPTPTTTTPVKVEKLLQSPIARLEARKKERRKQRPNSLESSAESEASGMDVDPSNPGQVDAVSSTANFKSPLSALGMGDSNDANASGCDKQSKKKRKRCGECVGCQRKDNCGECAPCRNDKSHQICKQRRCEKLTEKKIVFGADGQPVRPDSKRGRGKGKSSGSGNGTVNATGIAAGNGTPTTGQSRARKNSTKANKLNAAAASATSPRLSPVPAATLLPQQSPNTTSATGNLQQQQQQQQQQYQQHQQLLSQQQLLSQQQQQYQQPQQQQQHFQQQQQQHLQQQHAQQQHLPQQQHQITAQIQTMKDQPQQPMAPMAFYPTWQADPSQGWQNQFIQQIPQNTPAITSLNSLDFQTQSYAYPSNGYVQSGLGFDPNYGRSPYAAPVQRYDFQSQQLSTAPSAINQVGLQSVAGFAPSYAGQVSAAPVPPSQQQQQQQQQQQQQHLGADLNKTMSGNDTPGYPRVSSVPPRSLNCNGYSGDYSGSPATNSNSNNNSSSNTSNTNNSNASNNNATTVVSGGTTTPAPPPTVVAQPASSPMQPPNQAVPQSPTRSNMLQQQQQQHQSPTGNGLQPYVAPQQQQQQQQQQHLSSPPMQDWNWQQQQQQQQSLGGEGYAQGERLHLNTRIKSMIMRKSDPKDPPPDLQQQPQQVQQQQQTGHFLSYSHHLRPEAALSANGPSSATPTHPLPNLQQQQQQVQQVQQVQQQQQQQQAVGGQVAAEPIGGGGDHIWKPHHANSFKKPSVVSGYPASQDAQLQLQLQQHQPGQHTTINHSVDPPVVPPQQHPPVAAAQPKKSRSRSKASRAAAAAAAAAEAAAEIDRDRNSTDPGGGGLKPLSAHYPPHPHAAGGPPPGQDYHSQYIKTEPGLLGPPQPNKMEGYERNYQNFIQYADFCQNDGQGQPVQQHHGHGQQDYAGYHHNSAYYGAGASSFQQNFQQNFVPGYQHSTYGARGKPPANQPHQIHGHGQSLMELDRKPDTNSIIPLPTNYEKDIPAYPIPPHRYALGHGAPPHLSHHGMLEPKIEDMGMLGHGGGYAYLGSEGKPLNNGFSCCRQGGTRPPTAEHLKDGTCLGLGIQPKEELIDEDELIDTHGNGLKPIGGVGKAKGKQKPDEIPEIVVKHEKINPMFDTTDRLEKGNKTEIPECECFQSDKNPPEPGTYYTHLGTASSLMDLRREFEERCNLTGRQLRIEKIVYTGKEGKTSQGCPVAKWVIRRADLEEKILVVVKKRPGHRCIAAYIVVCMVAWDGMPRLEADNAYKNLIPKLNKYGLPTTRRCATNENRTCACQGLDPESSGASYSFGCSWSMYYNGCKYARSKTVRKFRLSVKSEEAAIEDHMNLIATLLAPVFKQVCPRSYDNQTKYEHEASDCRLGLEPGKPFSGVTACLDFCAHSHRDLHNMQDGCTVHVALLKPGNRDTRLPDDEQFHVLPLYTMDGTDEFESVEGQRDKHRTGAVQMLDKFPCEVRVRSTPLIPCRRHGKKRKDGDEAAPPDGDQDAVGDANSQSSSSNGAQSQTQANNQQSSPPALGTAHIKKENGNGVNANGASSKSKGKGKSNQSNNSSASTPGSAPPSTPSPRCQTPVTNNPSPAGSAFSTPPVHGSNANPQSNGGQGTGNQPGQLMSSNSSLMNMATMIDTFTDAQLQSNQISSTVLDSPYSYDYQTASYIDSRNYYGQWPTPHAPMGMQAQVGGLGGGGPGGTVAGVPPLTPSTPTAQPQLGVPPATSIAGGTTTGAPTGALPATAPPTATPTQLETSNGYGPGNYQTLVSNPASNLTNPGGVTTEVQQQHQQAQQQSALTGGVGPGGLPVVGGAPGDLKGRLVSEENPDSTTLVNHHHHHHNLTESKLTALTAMQPMTNLAPLTTSHHPQEGFVKPKPPPSDYTAQYTAQYPNNYQMYPPPPPPPHSAYSAYDAYQNMNYNYGYHQAYSPYGMYPQQTPPPTPPPPSPNWNMYGHHQTGSVNSGYGSANPAAGAGSLISSHGSVASAGVGLQKAMVPVPGPLHHQQQQVLQQQQQQQQQQQQQQQQQQQQQQQQVQQLQQEAPQTILPDLSNGQTNSDTVATPTPTGDSSSNDAGPGNPGAGNQAPASGAGAATTAPPIASPGSTNSTKIEPIGEVAEINENIEAFQDPQMGGVAIALNHGSVLIECAKHEMHATTAVRRPDRHHPTRMTLIFYQHRNLNRCRHGIDEWEEKMRVKKINTDLDNKAKEERERLIKKAAGEDMDELDEDALMQDEPVPIKKESSANGQQLKNGASGSKKKKSSDSKKSQANEQSKNEKVALHAPTLTTTSWTTLFPTHPCVVSGKYPEGNSSPTSSTNNAPNGGGCPAQQQQHLPPPPGSGLIHPPPGTPTGTAAPPPLPTPHQQLPQQQQT

tet

Tetracycline resistance protein

459 amino acids

Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

Belongs to the major facilitator superfamily. TCR/Tet family.

50.695 kDa

MFSLYKKFKGLFYSVLFWLCILSFFSVLNEMVLNVSLPDIANHFNTTPGITNWVNTAYMLTFSIGTAVYGKLSDYINIKKLLIIGISLSCLGSLIAFIGHNHFFILIFGRLVQGVGSAAFPSLIMVVVARNITRKKQGKAFGFIGSIVALGEGLGPSIGGIIAHYIHWSYLLILPMITIVTIPFLIKVMVPGKSTKNTLDIVGIVLMSISIICFMLFTTNYNWTFLILFTIFFVIFIKHISRVSNPFINPKLGKNIPFMLGLFSGGLIFSIVAGFISMVPYMMKTIYHVNVATIGNSVIFPGTMSVIVFGYFGGFLVDRKGSLFVFILGSLSISISFLTIAFFVEFSMWLTTFMFIFVMGGLSFTKTVISKIVSSSLSEEEVASGMSLLNFTSFLSEGTGIAIVGGLLSLQLINRKLVLEFINYSSGVYSNILVAMAILIILCCLLTIIVFKRSEKQFE

tet

Tetracycline resistance protein

459 amino acids

Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

Belongs to the major facilitator superfamily. TCR/Tet family.

50.695 kDa

MFSLYKKFKGLFYSVLFWLCILSFFSVLNEMVLNVSLPDIANHFNTTPGITNWVNTAYMLTFSIGTAVYGKLSDYINIKKLLIIGISLSCLGSLIAFIGHNHFFILIFGRLVQGVGSAAFPSLIMVVVARNITRKKQGKAFGFIGSIVALGEGLGPSIGGIIAHYIHWSYLLILPMITIVTIPFLIKVMVPGKSTKNTLDIVGIVLMSISIICFMLFTTNYNWTFLILFTIFFVIFIKHISRVSNPFINPKLGKNIPFMLGLFSGGLIFSIVAGFISMVPYMMKTIYHVNVATIGNSVIFPGTMSVIVFGYFGGFLVDRKGSLFVFILGSLSISISFLTIAFFVEFSMWLTTFMFIFVMGGLSFTKTVISKIVSSSLSEEEVASGMSLLNFTSFLSEGTGIAIVGGLLSLQLINRKLVLEFINYSSGVYSNILVAMAILIILCCLLTIIVFKRSEKQFE

tet

Tetracycline resistance protein

458 amino acids

Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

Belongs to the major facilitator superfamily. TCR/Tet family.

50.093 kDa

MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVYKHSQRDF

tet

Tetracycline resistance protein

458 amino acids

Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

Belongs to the major facilitator superfamily. TCR/Tet family.

50.093 kDa

MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVYKHSQRDF

tet

Tetracycline resistance protein

458 amino acids

Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

Belongs to the major facilitator superfamily. TCR/Tet family.

50.119 kDa

MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLLFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVYKHSQRDF

tet

Tetracycline resistance protein

458 amino acids

Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

Belongs to the major facilitator superfamily. TCR/Tet family.

49.954 kDa

MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPIITIITVPFLMKLLKKEVRIKGHFGSKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRVPLYALNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSLLSEGTGIAIVGGLLSIPLLDPRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNLYKHSQRDF

tet

Tetracycline resistance protein

458 amino acids

Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

Belongs to the major facilitator superfamily. TCR/Tet family.

50.006 kDa

MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIVGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNILFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTAFFLLETTSWFMTIIIVFVLGGLSFTKTVIPTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMGVDQSTYLYSNLLLLFSGIIVISGLVTVNVYKHSQRDF

tet

Tetracycline resistance protein

458 amino acids

Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

Belongs to the major facilitator superfamily. TCR/Tet family.

50.093 kDa

MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVYKHSQRDF