Protein
Transcription factor 7-like 1-D
Function
Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early in development for the establishment of the dorsal body axis in response to maternal Wnt signaling (By similarity).
Similarity
Belongs to the TCF/LEF family.
Sequence
MPQLNSGXGDELGANDELIRFKDEGEQEEKSPGEGSAEGDLADVKSSLVNESENHSSDSDSEVERRPPPRETFEKPRDYLSEAFRRQQDAAFFKGPPYAGYPFLMIPDLGGITCPMVPSHPALAYLQMKWPLLDSPSTAGLKDARSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNEHFSPGTPPGHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSIPPGGFRHPYPALAMNASMSSLVSSRFSPHMVPPPHHSLHTSGIPHPAIVSPIVKQEPSSGNISPNLSMKSNVVVKKEEEKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHSLSREEQAKYYELARKERQLHSQLYPSWSARDNYGKKKKRKREKQSPEMENYTKTKKMCVQHFPSDKSCDSPASSHGSMLDSPATPSAALASPREPAATHSEEAQPLSLTTKPEARALSHSAAFLASKSPSSSSLSGHLPSPVGSPLLSRPIPLTSSILSPPGVFPPALQALPLLQAQPLPLVARSSD