Protein
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 2
Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Function
S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.
Similarity
Belongs to the TYW3 family.
Sequence
MKAKREALISLFHAIKEEKVDSDIIDLLLLINSIKGIYTTSSCSGRIGILEEPSLGAKPLSRWLIKVHRPMSFEEARDALKRAREGLIFLKSQPPIFHVVAETIENAKLVHEIGLASGFKYTTFKAISSRFLVEINGTEYLTVPLGKDGRIIASDEYLKFAISIGNKMLERGKSKLPRLRDNFEKIKKKLGEDPLFIQLKREILEI