taw22

Gene

taw22

Protein

tRNA (guanine(37)-N1)/4-demethylwyosine(37)-methyltransferase Taw22

Organism

Pyrococcus abyssi (strain GE5 / Orsay)

Length

333 amino acids

Function

Catalyzes both the N1-methylation of guanosine and the C7-methylation of 4-demethylwyosine (imG-14) at position 37 in tRNA(Phe).

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.

Mass

38.478 kDa

Sequence

MSGVKVRREDAKKVLELLKSVGILDGKRKAIRDEKYVIFPVTDTNIAKSLGLEVVDVELPMRPERQIYKNLEDLLPREIFKKLGRLDIVGDIAIVSIPDEILSEREVIVSAIRKLYPKVKVIARRGFHSGLYRIRELEVIWGENRLHTIHKENGVLIKVDLSKVFFNPRMKGERYRIAQLVNDGERILVPFAGVIPYPLVIARFKNVEVYAVEINEFAVKLAEENLELNRDRLKGKIKIIHGDVFEVLPNLPNFDRVVSPTPKGVDALSLTLSKAEKFLHYYDFVHESEIERFRERVLEECRRQGKECRVSVRKVSDYKPHVYKVCADVEILS

Protein

tRNA (guanine(37)-N1)/4-demethylwyosine(37)-methyltransferase Taw22: taw22

Gene

taw22

Protein

tRNA (guanine(37)-N1)/4-demethylwyosine(37)-methyltransferase Taw22

Organism

Nanoarchaeum equitans (strain Kin4-M)

Length

297 amino acids

Function

Catalyzes both the N1-methylation of guanosine and the C7-methylation of 4-demethylwyosine (imG-14) at position 37 in tRNA(Phe).

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.

Mass

35.106 kDa

Sequence

MSYDIIGEIAIIYPPVDDLDKIVNKILKHHKYVKAIYLKTDKLETELRLPKLKLLYGEPILETTYKENKCVFKLRVDKVYFSPRLSTERKEFIDLVKDNEKILIPFAGVNPYPIVIAKHRKVQIKSIELNPWAVKYGIINTKLNKVNVDTILADFGIAWKYIRNLHNKEGIVTKYVNELLKAKPELDLVYTNEEYYDLLNQYYNTKLIEELKPGIEYFDRIIMPLPKGGEHFIFEALVLAKKYIHLYSFAHEKEIEQKVKEIIDIASQLREIKHYDYKIVGDIGVRKYRIRINIYLI

Protein

tRNA (guanine(37)-N1)/4-demethylwyosine(37)-methyltransferase Taw22: taw22