Function
Involved in microtubule formation, polymerization and assembly, regulating microtubule nucleation and length (PubMed:12956950, PubMed:12956951, PubMed:16054029). Plays a role in pronuclear migration and mitotic and meiotic spindle elongation during early embryogenesis (PubMed:12956950, PubMed:12956951). In complex with zyg-9, functions during the early stages of embryonic development to regulate microtubule assembly throughout the cell cycle (PubMed:12956950, PubMed:12956952). Specifically, the complex is required for the formation and growth of astral microtubules and spindle microtubules during mitotic spindle assembly (PubMed:12956952). At anaphase, the complex is required for mitotic spindle positioning in one-cell stage embryos (PubMed:17666432). The complex acts in a partially redundant manner with the tac-1/zyg-8 complex to regulate microtubule assembly and processes during interphase, mitosis and meiosis in embryos (PubMed:17666432). Plays a role in injury-induced axonal regrowth, regeneration and microtubule stability in PLM neurons and this may be downstream of efa-6 (PubMed:26339988).