swnT

Gene

swnT

Protein

Swainsonine transporter swnT

Organism

Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)

Length

498 amino acids

Function

Transmembrane transporter; part of the gene cluster that mediates the biosynthesis of swainsonine, a cytotoxic fungal alkaloid and a potential cancer therapy drug (PubMed:28381497).

Similarity

Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid/choline transporter (ACT) (TC 2.A.3.4) family.

Mass

54.221 kDa

Sequence

MSLRNDEQTEKGAVVGKVDSQLSGPGQEEIIQVQTQKPFTTLSAIGIGYGVTNTAVGLLLVLGTGIPMGGSPVIFWGFLAMAAVGLATATTLSELISAIPHPGGQYIWVHKIAPERYRRGLSYATAMISWIAAIAIGASGNLAVPVNAFTIVTLLNPNFVYQRWMGFVVFQLINIVTCFGACFEYFLPKISKALLLVNVLSVSAIIITLFATAKTHTSAKDFFKVVNVSGWPNGVAFLIGLNGSNWCFSCLDVATHLAEEIPSPSTNIPKALIWTIVIAFSSGLLMILAVLVNVGPINTPDYSGLTVLHHITGSKAAAIGLWVPVLFLVFASVWSIQTWQSRLAWSISRESGFPLHRHFSKIFPAPFYTPIWSLIGSAIGTALFGCLYLASELAFNSLIATGILLQYASYSIPTILVLYRGRSKFQHGPFWYPKLGFMANIVMLAWTLVALIFYCFPVYSEVIPSQVNYVSAVLILIAILITSLWFLYAKKHYHVVEI

Protein

Swainsonine transporter swnT: swnT

Gene

swnT

Protein

Transmembrane transporter swnT

Organism

Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075)

Length

496 amino acids

Function

Transmembrane transporter; part of the gene cluster that mediates the biosynthesis of swainsonine, a cytotoxic fungal alkaloid and a potential cancer therapy drug (PubMed:28381497).

Similarity

Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid/choline transporter (ACT) (TC 2.A.3.4) family.

Mass

53.807 kDa

Sequence

MAKLGTMPPQHAAKPVDEHAARLIPEDSVPIQTQKPFTTLSAIGIGYGVTNTAVGIPLILSTAMPMGGSPQVFWGFLAMAAVGLATATTLAELVSAMPHPGGQYIWVNALAPKRYRRGLSYTTAMISWVAAVATGSSGNLSVPLNAFSIVTLLQPDFVYRRWMGFAAFQAINVVTCFGACFEHALPKLSKAFLLFNVVSVGVIIVALFAMADARTSAKDFFTTVNTSGWPDGVAFIIGLNGANWCFSCLDVATHLAEEIPSPGTNIPKALLWTIFIASTSGLLVVLAVLVNLGPVDVSDYSGIGIFYRITGSKAAAIGLWIPVLILVLASVWSIQTWQSRLAWTISRESGFPLHRHFSKIFPAPFYTPIWSLVGSAVGTALFGCLYLASELAFNSLIATGILLQYISYSIPTVLVLWQGRRNFRHGQFWYPRLGLVANFIMLAWTVVAFVFYCFPANAQVRPSQMNYVSGVLVVIATFIAALWILYARKNYRVMEI

Protein

Transmembrane transporter swnT: swnT