sur2

Gene

SUR2

Protein

Sphingolipid C4-hydroxylase SUR2

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

349 amino acids

Function

Required for hydroxylation of C-4 in the sphingoid moiety of ceramide. Involved in the response to syringomycin.

Similarity

Belongs to the sterol desaturase family.

Mass

40.734 kDa

Sequence

MNVTSNATAAGSFPLAFGLKTSFGFMHYAKAPAINLRPKESLLPEMSDGVLALVAPVVAYWALSGIFHVIDTFHLAEKYRIHPSEEVAKRNKASRMHVFLEVILQHIIQTIVGLIFMHFEPIYMTGFEENAMWKLRADLPRIIPDAAIYYGYMYGMSALKIFAGFLFVDTWQYFLHRLMHMNKTLYKWFHSVHHELYVPYAYGALFNNPVEGFLLDTLGTGIAMTLTHLTHREQIILFTFATMKTVDDHCGYALPLDPFQWLFPNNAVYHDIHHQQFGIKTNFAQPFFTFWDNLFQTNFKGFEEYQKKQRRVTIDKYKEFLQERELEKKEKLKNFKAMNAAENEVKKEK

Protein

Sphingolipid C4-hydroxylase SUR2: SUR2

Gene

sur2

Protein

Sphingolipid C4-hydroxylase sur2

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

293 amino acids

Function

Required for hydroxylation of C-4 in the sphingoid moiety of ceramide. Involved in the response to syringomycin (By similarity).

Similarity

Belongs to the sterol desaturase family.

Mass

34.191 kDa

Sequence

MVTTVEMLTTWNPVTVSLVSPVIIYWVASAFFGFLHYIELPVFEKYRIHPPEEIARRNRVPQMAVVKAVLFQQLCEVVVGIALAMFEGYPEPIDEAKQMLRYEAFFSKNLPALLQVAPFAPKLAYNFIVPAFQYFFAFFIIDSWQYFWHRYLHYNKKLYNMIHAHHHRLQVPYAMGALYNHPFEGLILDTFGAGVAYLAAGLSPQQAVIFFTLSTLKTVDDHCGYVFPYDPLQMFFANNARYHDLHHQPYGFQKNFSQPFFTFWDHVLGTYMPPKSETPYEKKQKAKNAKKVN

Protein

Sphingolipid C4-hydroxylase sur2: sur2