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strB2

Gene
strB2
Protein
Putative inosamine-phosphate amidinotransferase 2
Organism
Streptomyces griseus
Length
349 amino acids
Function
It is not obvious if strB2 participates in streptomycin biosynthesis as an inosamine-phosphate amidinotransferase. Attempt to measure its activity have failed and the nucleophilic cysteine which is the key residue for amidine transfer is not conserved but replaced by a glycine residue.
Similarity
Belongs to the amidinotransferase family.
Mass
38.219 kDa
Sequence
MSLVGVHNEWDPLEEVVVGTARRPCAGPDRSLLAVEYAEYAGPGRWQEVPTGPYPDRALKETEDELEELCEELRGLGVTVRRPGARDSAAPVRTPDWESDGYGDLCPRDGLLVVGDTVIEAPMALRARFLESLAYKELLVEYLAAGSRWISAPKPRLAEGMYSPSGPSGERLRDLEPVFDAANVLRLGTDLLYLVSDSGNELGARWLQSALGAAYTVHPCRGLYSSTHIDSTLVPLRPGLVLVNPARVTDDNLPGVLRTWQRIECPALAGLGYAGDVPHCSTWIGMSLLVVRPGLVVVDSRHRELMRVLERHGVDVLPLKLTHARMLGGGFHGVTLDIRRTGALETYRF

Gene
strB2
Protein
Putative inosamine-phosphate amidinotransferase 2
Organism
Streptomyces glaucescens
Length
319 amino acids
Function
It is not obvious if strB2 participates in streptomycin biosynthesis as an inosamine-phosphate amidinotransferase. The nucleophilic cysteine which is the key residue for amidine transfer is not conserved but replaced by an arginine residue.
Similarity
Belongs to the amidinotransferase family.
Mass
34.614 kDa
Sequence
MSLAGVYTEWDPLEEIVVGTAVGSENRMVRETEDELDGLCEELRGLGVTVRRLPPQDPASPPAPPDRGADTALAYRPRDGLLTVGETVIQTPAVPGLPSLQSPACRMLLMEYFTSGSRWISAPPPVLTDVMYDPTAPAGERLRELEPVFDADTVLRIGTDLLYLVSDSGNALGARWLQAALGERYTVHPCRGPHGSPHGDFAVVPLGPGLILVNPERVDAEHIPPFLRTWKRIVCPELVDPGPPDGAVHSSGWGGSNILVVRPGLVIVDRRQADLMRVLENNGIDVLPLQLTHARALGSGFHRVTVDVRRTGTLESYRF