Protein
Putative inosamine-phosphate amidinotransferase 2
Organism
Streptomyces griseus
Function
It is not obvious if strB2 participates in streptomycin biosynthesis as an inosamine-phosphate amidinotransferase. Attempt to measure its activity have failed and the nucleophilic cysteine which is the key residue for amidine transfer is not conserved but replaced by a glycine residue.
Similarity
Belongs to the amidinotransferase family.
Sequence
MSLVGVHNEWDPLEEVVVGTARRPCAGPDRSLLAVEYAEYAGPGRWQEVPTGPYPDRALKETEDELEELCEELRGLGVTVRRPGARDSAAPVRTPDWESDGYGDLCPRDGLLVVGDTVIEAPMALRARFLESLAYKELLVEYLAAGSRWISAPKPRLAEGMYSPSGPSGERLRDLEPVFDAANVLRLGTDLLYLVSDSGNELGARWLQSALGAAYTVHPCRGLYSSTHIDSTLVPLRPGLVLVNPARVTDDNLPGVLRTWQRIECPALAGLGYAGDVPHCSTWIGMSLLVVRPGLVVVDSRHRELMRVLERHGVDVLPLKLTHARMLGGGFHGVTLDIRRTGALETYRF