Protein
Peptidyl-prolyl cis-trans isomerase ssp-1
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
Site-specific PPIase with respect to the amino acid N-terminal to the proline residue. Peptides with glutamate, phosphoserine, or phosphothreonine in the -1 position are the best substrates. It is not only able to isomerize small peptides but is also active in protein folding.
Sequence
MSNTIETGLPEDWEVRHSQSKNLPYYFNSATKTSRWEPPSGTDVDKLKIYMAKYHSPTSQQQQQQQQQQPQGKIRCAHLLVKHNQSRRPSSWRESEITRTKQEALTTLQGFEQRIKSGSISLGELALTESDCSSARKRGDLGYFGRGDMQKEFEDAAFALKPGEISGIVDTASGLHLIERLE