Protein
Manganese ABC transporter substrate-binding lipoprotein
Organism
Streptococcus sanguinis
Function
Part of an ATP-driven transport system for manganese. Also acts as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in the pathogenesis and infection. It may contribute to the formation and accumulation of dental plaque.
Similarity
Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily.
Sequence
MKKLGFLSLLLLAVCTLFACSNQKNASSDSSKLKVVATNSIIADITKNIAGDKIDLHSIVPVGKDPHEYEPLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVKNANKEENKDYYAVSDGVDVIYLEGQSEKGKEDPHAWLNLENGIIYAQNIAKRLIEKDPDNKATYEKNLKAYVEKLTALDKEAKEKFNNIPEEKKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKSLVEKLRKTKVPSLFVESSVDDRPMKTVSKDTNIPIHAKIFTDSIADQGEEGDTYYSMMKYNLDKISEGLAK