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srb-13

Gene
srb-13
Protein
Serpentine receptor class beta-13
Organism
Caenorhabditis elegans
Length
345 amino acids
Function
G-protein coupled receptor that antagonizes the negative effects of the gcy-35 oxygen sensor on spermatogenesis (PubMed:28662030). This leads to the maintenance of mitochondrial function in developing spermatocytes and/or spermatids prior to testis maturation during the early larval stages (PubMed:28662030). Regulates the navigational capacity of sperm during hyperoxic conditions ensuring the proper targeting of sperm derived from males to the fertilization site in the uterus of hermaphrodites (PubMed:28662030). May act in the same signaling pathway as the neuropeptide flp-21 (PubMed:28662030).
Similarity
Belongs to the nematode receptor-like protein srb family.
Mass
39.809 kDa
Sequence
MAGINQTKCDLGFQITFNTVYRFSQFYTFSVSSFAVPGLIYFMFKRLFQLYFHGNLKTLLIAYFISILLYAVMLCFAFGYQFFVPFFIKSNCDLIINKTLFKYIHTSVIFLLTTPMMFPLGFSIERFTAMAMASRYENIRTLIGPVLVIFLIIPNCIIFYFLFQHETYDDTFISFLMLPNTTAVNFNTYLWFLLYLNIGNLALNVLLLLVHRKFKRRLLLHKTSLSTRYAIEEISQSSKFTLIITFTHLLFFGCNTICSILVRVLGEPFFGSFINHSVARGVNCAVPTYNLVIVVVGFVSLSKLNSRRQQEVQTTVQLKTTGKEGARNYDNITANQWATITQIGF