About Products Protein Database Contact

sqv-7

Gene
sqv-7
Protein
UDP-sugar transporter sqv-7
Organism
Caenorhabditis elegans
Length
329 amino acids
Function
Involved in the import of UDP-glucuronic acid (UDP-GlcA), UDP-N-acetylgalactosamine (UDP-GalNAc) and UDP-galactose (UDP-Gal) from the cytoplasm into the Golgi lumen for the biosynthesis of glycoconjugates that play a pivotal role in development (PubMed:11259660). Involved in the synthesis of chondroitin sulfate and heparan sulfate proteoglycans (PubMed:11005858). Required for embryonic development (PubMed:9927677). Involved in vulva epithelium invagination and embryonic development (PubMed:9927677, PubMed:11259660). Involved in the directed migration of hermaphrodite-specific neurons (PubMed:24052309).
Similarity
Belongs to the TPT transporter family. SLC35D subfamily.
Mass
36.893 kDa
Sequence
MTSTVQSPLYSRVFSAVFYGVISVLIVFVNKILLTNYKFPSFLFVGVGQMMATILILFFAKMFRIVQFPSLDSSIPRKIMPLPLLYFFNLISGLGGTQMINLPMFTVLRRFSILMTMILEFYILNVKASKAVKISVGLMIGGSFIAAIYDLSFDALGYTMIFINNICTAALGVYTKQKLDAKDLGKYGLMFYNCLFMLLPALCVVQYTGDLDRAYSFMLSDSMTSSVWTCFLLSCICGFVLNYSLVLCTHHNSALTTTCVGPIKNLFVTYVGMFSSGDYVFQWANFTGINVSVFGSILYTYVTFRSKSTTISYKPLPMTMPIDVHKPRN