spz3

Protein spaetzle 3

611 amino acids

Neurotrophin which may function as a ligand to the Toll-related receptor Tollo. Involved in a Tollo and JNK signaling pathway that positively regulates neuromuscular junction (NMJ) growth in presynaptic motorneurons. May function by activating Tollo to promote the phosphorylation of JNK.

67.126 kDa

MALTNFSLPFGALGQPWGVTIAPLHPIHQLASNTNNLLYSPADHQQQTPAEAAADPEYFKNNPYAPPQSGGYQYQNTAGRRKQSNAYLPPTAPNAVRNSVYHIQQVQQTQQQQTQQQHQQQDQHENSVSFQSSSSRSSSSSTTGQSSIQLTQTHASGRGPAEGSYSRYPGQQAQPPQQQQPQQKQYFNAHGSASATFTKNSGSFSITSFGSRQQQQQPPQPQQPPPSQQQQPPPAPPPQRSRQAKPEAQPAQTYGVAPPENYPERAPGFTRVQAGQGSRTQVHAVLDYDVEEGEEDEEEDGEEEGQFYEGQENDKSNNNQMPTVTPIQGPIYLKNGTVPVVPLFSYPKLNNGSFLQIPIWWTALSVALGLDVRGDVIKGVPCIKRYHQLFCPTAGNSYPIDKIERFIDDNKALMRRMYGDFEMNMEGPGGGGGRQQGKVRKRRFIDEPDIFIPPGAFAANAGETVEAGDSYFGQLRKKRQAAAGGSRNRGGSAGGSGNGNTNANRQPGNKNGSSGTGRLDACESKIEIVTPYWASNSAGKIRAIVNTQHFEQAIHQEVCSNTQTPRCEGECGCEQKYKWHRLLAYDPDNDCKGIFMDWFLFPSCCVCRCNP