spk-1

Serine/threonine-protein kinase spk-1

1132 amino acids

Required for embryogenesis and germline development in both adult hermaphrodites and males. SR-protein kinase (SRPK) that binds directly to and phosphorylates RS domains (By similarity).

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

126.2 kDa

MLSILHSLSWMAHWINPTATIAPSTPPQAGEKNANVKNGTVQTNGVNHTERLAGRAPNLLHPAIDYPGITSYEAGGSLILTDIFPTVLFMFVVLFCRWFNGFAPRQERFQRLEYEAILRRRRFRVQSEESEELEDHEAYSETDICTQLIASSANVACNINVDLVNQNRFYFFVKQNNEDETAVPSDVPPPETSIKNEDTEVNLVFASAEDNGYISSTFEVSETSLMVTSEVYEVEKVSVNEDQSSRPVNVIVNESDDEQSLRSQDGSRCSDEAMNSCMSASEDEDVESQEDSYHVNDATEDSVSSIKTQEDEPIEEELASCHSDEDDHQNEVLGDEEASKYDNLPVEMRSAKEGDESEGTIDSSVSSSTSSTPDDDEDDSATSYDSDDIEIQMFEYDLGTVCASASISIPRPSIIPKKNKKAEVNANEERMDDVSVSPGRSDSPGGGGGHSDSFQDPLDPGEQLGSDDEEQEDPRDYKRGGYHPVNIGDVFNSRYHVIRKLGWGHFSTVWLAWDTQEKRFTAMKIVKSAEHYTEAALDEIKLLLSVRGADPEDTGCHKVVQLLDEFTVTGINGQHVAMVFEVLGCNLLKLIIRSNYRGLHLEQVRKICKQILEALRYMHEKCGIIHTDIKPENVLITMSREEIKIMAQHAVVARKMNMKMSGSAVSTAPDHLVKMAQENMTKNKKKKMKKKAKKQREKLEAELAGLEGLKMDANGLQEAYNNAPQNGIRMRPPSLLFNGPIPQLLQGSSCVNTPSSPRSVPPPPALYPQAGGVCNQTYHLSQVILNEQVELESFNTSQVEDVNIEDAVNGNGNGTNNKIELKSPDRFDRTTLTPFSDPESKIGELASPSSEFLSSPMSMLPPGGVLPAPPVGPNIADPYCDIDVKIADLGNACWVNHHYTDDIQTRQYRALEVLIGSGYGPPADIWSTACMAFELATGDYLFEPHQGDNYSRDEDHLAHISELLGQISPSIYKKGKHWREFFHKNGNLLHIHNLKPWSLYEVLRQKYEWSHEDAQQFESFLRPMLDFDQEKRATANDALKHPFLLPFGGKAPRDPEVLQRLYPDGQVPEALDGNQEVYRDENDSNSASERSANRSAGSDDEEEFHMDRPGPSGVINEPADVSEIESFQLNLQ

spk-1

Serine/threonine-protein kinase spk-1

1003 amino acids

Required for embryogenesis and germline development in both adult hermaphrodites and males. SR-protein kinase (SRPK) that binds directly to and phosphorylates the RS domain of rsp-3/CeSF2 in vitro.

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

112.527 kDa

MFVVLFCRWLNGFSQHRERLYKFEDEAVQRRRRFRVHSEESEELNDHESYSETDICTQLLASSADVTCHINVDLVNQNRFYFFVKQRNKKENSTNEEEEISSQEINTSTQNEETEVNLVFASAEDNGGVASNFDISDALMVTSNISEVSKLPETLCEEGETVQQKSVVNENDHSNEDDEQSLQSQDGSRCSDEDMNSCVSASDEEDVESQDDSFHVNDATEESIDSVSSIESQEAEESATEDLASCHSNDDKNEKDVLVDEDTSKYDNLPVEMRSAKEGEESEGTIDSSVSSSTSSSSTGDDGDDSATSYDSEDIEIQMFEYDLGTACASASISIPRPSIIPRNNKKTEVNANEERLDDLSVSPGRSDSPGGGGGGHSDSFQDPMDPGEQLGSDDEEQEDPRDYKRGGYHPVNIGDVFNARYHVIRKLGWGHFSTVWLAWDTQDKRFVAMKIVKSAEHYTEAALDEIKLLLSVRSADPNDIGCHKVVQLLDEFTVTGINGQHVAMVFEVLGCNLLKLIIRSNYRGLHLEQVRKICRQVLEALGYMHEKCGIIHTDIKPENVLITMSREEIKIMAQHAVVARKMNMKMSGSAVSTAPDHLVKMAQENMTKNKKKKMKKKAKKQREKLEAELAGLEGLKMDANGLQEAYNNAPELENFNASQVEDVTMEDTVNENGNRNKVEIRSPDRFDRTTLTPFSDPESKFGDLASPSAEYLSSPMSQLPPGGILPAPPVGPNIGDPYCDIDVKIADLGNACWVNHHYTDDIQTRQYRALEVLIGSGYGPPADIWSTACMAFELATGDYLFEPHQGDNYSRDEDHLAHISELLGAIPPSIYKKGKHWREFFHKNGHLLHIHQLKPWSLYEVLRQKYEWSHEDAQQFESFLRPMLDFDQEKRSTAKIALKHPFLLPFGGRAPKSDCPPELLSKMFPDGLIPEPFDGNEHQEVYRDENDSRSASERSANSRSAGGSDDDDEEEFNMNRPGPSGVITNNETTDISDIERFQLDLQ