Function
Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on sphinganine (By similarity). Required for neurotransmitter release from neuromuscular junctions. Acts by recruiting the synaptic vesicle priming protein unc-13 to synapses (PubMed:22588719, PubMed:23223309) (Probable).
Sequence
MFIVVVTIFENYTQWYSSLLTIFSLTIKRKLKTIRSMQDSTSKCTCTEHHMGGTICCCCRSDAEENEQLTSVILSRKPPPQEQCRGNLLVFINPNSGTGKSLETFANTVGPKLDKSLIRYEVVVTTGPNHARNVLMTKADLGKFNGVLILSGDGLVFEALNGILCREDAFRIFPTLPIGIVPSGSGNGLLCSVLSKYGTKMNEKSVMERALEIATSPTAKAESVALYSVKTDNQSYASFLSIGWGLMADIDIDSEKWRKSLGHHRFTVMGFIRSCNLRSYKGRLTYRPYKPKGFHPSSNVFSVYEKTTQQRIDDSKVKTNGSVSDSEEETMETKFQNWTLPDSDETLAVGSSDLEETVVIEDNFVNIYAVTLSHIAADGPFAPSAKLEDNRIHLSYILWKDIGTRVNIAKYLLAIEHETHLDLPFVKHVEVSSMKLEVISEGSHVVLDGEVVDTKTIEVASTKNHISVFSSTA