Protein
Alkaline phosphatase synthesis transcriptional regulatory protein SphR
Organism
Synechococcus elongatus (strain PCC 7942)
Function
Member of the two-component regulatory system SphR/SphS. Response regulator. Involved in inducible production of alkaline phosphatase in response to phosphate limitation as it is directly involved in the regulation of phoA transcription in response to phosphate limitation. Binds to two distinct sites upstream from the phoA promoter.
Sequence
MTSNPLDESMESLTVVPPAASPASRILVVEDEAVIRDMVALVLQQEGFTVDVAADGRTALNYFRSDSPEAGSVTENPDLVVLDLMLPAVNGLDFCRLLRRQGVTVPILMLSAKDTETDRVVGLEIGADDYLTKPFGTRELVARCRALLRRSQNQPAETPAVLRYEGLKLFPEECRVLLDDRELTLSPKEFRLLELFMRHPRRVWSRDQLLEKIWGIDFMGDSKTIDVHIRWLREKIEANPSNPSYLLTVRGFGYRLG