SPE1

Arginine decarboxylase

607 amino acids

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

66.706 kDa

MAKNYGDVYHVEGWGEPYFAVNKDGHLCVRIYGRETLPGQEIDVLSVIEQATSADGTGKKLQFPMILRFPDVLRHRINSLHTAFANAIKYTQYGSVYQGVFPVKVNQHKDVVQDMVHFGYDHSYGLEAGSKPELLIAMSCLTKAKPGAYLVCNGYKDSAYVALALAARAMGLNVIIVLEMEEELDIVIEESSKLGVEPVIGVRAKLLTKIPGHFGSTAGKHGKFGLPAEKIYEVAKKLKALNKLHWLKLLHFHVGSMIPTTDIVFKAASEASDIYCALVKEYGVETMTTLDCGGGLGVDYDGTRSGSSDMSVAYGLEEYASSIVQAVRLKCDYHGVPHPVLCTESGRAMASYHSMIILEALSAIPEPKDDEDEATTEQLHGRIRDLSSKLQPTGLSMSSHAVHIKKHGIEMYKLGKKLSKSVTTDAHTIYNYHMNLSVFSLMPDYWGIQHLFPMMPVSRLDEKPTHKATLVDVTCDSDGKVDKFIRDTETMPLHPLDPKLGGYYVAVLLTGAYQEALSNKHNLFGGPSLVRVVGTGNGGAFNVEAALLGSTTEELIGTVSYDVKQDISSVIEERARENKVWEMVEKLVESGLHTMPYLADYKPPPMA

SPE1

Ornithine decarboxylase

466 amino acids

Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.

Belongs to the Orn/Lys/Arg decarboxylase class-II family.

52.285 kDa

MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDGETLHNLLLELKNNQDLELLPHEQAHPKIFQALKARIGRINNETCDPGEENSFFICDLGEVKRLFNNWVKELPRIKPFYAVKCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMNISPDRIVYANPCKVASFIRYAASKNVMKSTFDNVEELHKIKKFHPESQLLLRIATDDSTAQCRLSTKYGCEMENVDVLLKAIKELGLNLAGVSFHVGSGASDFTSLYKAVRDARTVFDKAANEYGLPPLKILDVGGGFQFESFKESTAVLRLALEEFFPVGCGVDIIAEPGRYFVATAFTLASHVIAKRKLSENEAMIYTNDGVYGNMNCILFDHQEPHPRTLYHNLEFHYDDFESTTAVLDSINKTRSEYPYKVSIWGPTCDGLDCIAKEYYMKHDVIVGDWFYFPALGAYTSSAATQFNGFEQTADIVYIDSELD

spe1

Ornithine decarboxylase

432 amino acids

Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.

Belongs to the Orn/Lys/Arg decarboxylase class-II family.

47.843 kDa

MPAIMEKNMLVSESLRTTELLGHVKPIDSVVTWSSPGSSRQAIGEAFKNTIEEIERAAVRGEPADSDAFFVADLNGVYRQLLRWHAKLPRVQPFYAVKCNPDPKVLALLNKFGTGFDCASKGELEQILGLGVSPDRIVYANPCKAITYVRYAASKGINLMTFDNADELYKVKQHHPNSRLLLRISTDDSNSLCRLSLKFGASLDDTGKLLDIAKSLELNVVGVSFHVGSGSYDPSAFLDAIQRSRQVFDQGLERGFNFDLLDIGGGFMNDSFDGVADLIRSALDTYFDPSIRVISEPGRFFVSSSFTLAVNVIAKRKLDDEEKVMYYVNDGVYGSLNCILFDHQHPVARVLKCGSRFVYNDLVGTGQHRCFIWGPTCDSLDVIANDAHLPYELNVGDWIYFEDAGAYTVAAASCFNGFKTSRIVYLDTDILD