SPAN

Protein SpAN

616 amino acids

67.902 kDa

MKLVLLLAGFAALAKCSLAAPAGVQKDIPMETSAPEKPSEATTLGLLKTPKPEPKDEEPSPGAFQGDMMLTDDQLRKVEEAIDDQKAGRKKRKATIYESQRWSYKIIPYVIESSSSGQSSLIRSAMDHWEQNTCLRFEPLTSSHSSRLGHTSYISFFRGNGCWSHVGRSFTNQQQISIGPQCGYFGTIVHEIGHAIGFHHEQSRPDRDEYINVHFENVQSGREHNFAKYTWGSVTSSNVEYDVGSIMHYGGYGFSSNGRPTITTIDPRLNSRLGQRTALSAADIELANRIYECDDVEDCSNADECLNGGYHDADCDCVCPSSYSGDLCQDGGPTVRPADCSYRFTEMTGEITSPNYPSNYEDNTACVYEIEGPYGSTIELTFLDMEIETETLCRYDAVEVRKDDINSIGEKFCGNTLPPVQISSSNQMMVSFTSDPSITRRGFKATYVIIIQTTTVFSTTTLQTTPPSTTTLQTTNPSTTTLQTTNPSTTTLQTTDTPVIGSCGGTFVGVEGRVASPNYPNDYDNSLQCDYVIEVDDGRRVELIFEDFGLEDETTCRWDSLMINLGNGIKVGMKMCGREYPAASLVSIGNRMELKLKTDGSVNDRGFVASYRAIDL

spaN

Surface presentation of antigens protein SpaN

336 amino acids

Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells.

Belongs to the SpaN family.

36.438 kDa

MGDVSAVSSSGNILLPQQDEVGGLSEALKKAVEKHKTEYSGDKKDRDYGDAFVMHKETALPLLLAAWRHGAPAKSEHHNGNVSGLHHNGKSELRIAEKLLKVTAEKSVGLISAEAKVDKSAALLSSKNRPLESVSGKKLSADLKAVESVSEVTDNATGISDDNIKALPGDNKAIAGEGVRKEGAPLARDVAPARMAAANTGKPEDKDHKKVKDVSQLPLQPTTIADLSQLTGGDEKMPLAAQSKPMMTIFPTADGVKGEDSSLTYRFQRWGNDYSVNIQARQAGEFSLIPSNTQVEHRLHDQWQNGNPQRWHLTRDDQQNPQQQQHRQQSGEEDDA

spaN

Surface presentation of antigens protein SpaN

292 amino acids

Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the ipa antigens. Required for invasion and for secretion of IpaB and IpaD proteins.

Belongs to the SpaN family.

32.978 kDa

MALDNINLNFSSDKQIEKCEKLSSIDNIDSLVLKKKRKVEIPEYSLIASNYFTIDKHFEHKHDKGEIYSGIKNAFELRNERATYSDIPESMAIKENILIPDQDIKAREKINIGDMRGIFSYNKSGNADKNFERSHTSSVNPDNLLESDNRNGQIGLKNHSLSIDKNIADIISLLNGSVAKSFELPVMNKNTADITPSMSLQEKSIVENDKNVFQKNSEMTYHFKQWGAGHSVSISVESGSFVLKPSDQFVGNKLDLILKQDAEGNYRFDSSQHNKGNKNNSTGYNEQSEEEC

spaN

Surface presentation of antigens protein SpaN

292 amino acids

Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the ipa antigens. Required for invasion and for secretion of IpaB and IpaD proteins (By similarity).

Belongs to the SpaN family.

32.978 kDa

MALDNINLNFSSDKQIEKCEKLSSIDNIDSLVLKKKRKVEIPEYSLIASNYFTIDKHFEHKHDKGEIYSGIKNAFELRNERATYSDIPESMAIKENILIPDQDIKAREKINIGDMRGIFSYNKSGNADKNFERSHTSSVNPDNLLESDNRNGQIGLKNHSLSIDKNIADIISLLNGSVAKSFELPVMNKNTADITPSMSLQEKSIVENDKNVFQKNSEMTYHFKQWGAGHSVSISVESGSFVLKPSDQFVGNKLDLILKQDAEGNYRFDSSQHNKGNKNNSTGYNEQSEEEC

spaN

Lantibiotic nisin-A

57 amino acids

Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.

Belongs to the type A lantibiotic family.

5.963 kDa

MSTKDFNLDLVSVSKKDSGASPRITSISLCTPGCKTGALMGCNMKTATCHCSIHVSK