SOX8

Transcription factor SOX-8

470 amino acids

May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.

50.83 kDa

MLNMTEEHDKALEAPCSPAGTTSSMSHVDSDSDSPLSPAGSEGLGCAPAPAPRPPGAAPLGAKVDAAEVDERFPACIRDAVSQVLKGYDWSLVPMPVRGNGSLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSENEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKAGQSDSDSGAELSHHAGTQIYKADSGLGGMADGHHHGEHAGQPHGPPTPPTTPKTDLHHGSKQELKHEGRRLVESGRQNIDFSNVDISELSSEVINNMETFDVHEFDQYLPLNGHTAMPADHGPGAGFYSTSYSHSAAGAGGAGQVWTHKSPASASPSSADSGQQRPHIKTEQLSPSHYSDQSHGSPAHSDYGSYSTQACATTASTATAAASFSSSQCDYTDLQSSNYYNPYPGYPSSIYQYPYFHSSRRPYATPILNGLSIPPAHSPTANWDQPVYTTLTRP

Sox8

Transcription factor SOX-8

464 amino acids

May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.

49.879 kDa

MLDMSEARAQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGGGGRGDTAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGTLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKTGRSDSDSGTELGHHPGGPMYKADAVLGEAHHHSDHHTGQTHGPPTPPTTPKTDLHQASNGSKQELRLEGRRLVDSGRQNIDFSNVDISELSSEVISNMDTFDVHEFDQYLPLNGHSALPTEPSQATASGSYGGASYSHSGATGIGASPVWAHKGAPSASASPTEAGPLRPQIKTEQLSPSHYNDQSHGSPGRADYGSYSAQASVTTAASATAASSFASAQCDYTDLQASNYYSPYPGYPPSLYQYPYFHSSRRPYASPLLNGLSMPPAHSPSSNWDQPVYTTLTRP

sox8

Transcription factor Sox-8

462 amino acids

May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3' (By similarity).

50.712 kDa

MLKMTEEHDKCVSDQPCSPSGTNSSMSQDESDSDAPSSPTGSDGQGSLLTSLGRKVDSEDDERFPACIRDAVSQVLKGYDWSLVPMPVRGNGSLKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVDEAERLRIQHKKDHPDYKYQPRRRKNVKPGQSDSDSGAELAHHMYKAEPGMGGMGGITDAHHHAEHAGQPHGPPTPPTTPKTDLHHGAKQDLKHEGRRLIDSSRQNIDFSNVDISELSTDVISNMETFDVHEFDQYLPLNGHTSSSSSLPSDQPPAPVSSYASSYGHAGVNGPAWSRKGAMPSSSPSSGEVGQHRLHIKTEQLSPSHYSEHSHRSPPHSDYGSYSSPACVTSATSAASVPFSGSQCDYSDIQSSNYYNPYSSYSSSLYQYPYFHSSRRPYGSPILNSLSMAPAHSPTGSGWDQPVYTTLSRP

sox8

Transcription factor Sox-8

459 amino acids

Transcription factor. Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox9 and sox10 to induce neural crest progenitors. Regulates the onset of expression of many neural crest marker genes including sox10, and regulates the development of multiple neural crest derivatives. May be required to regulate neural crest cell migration.

50.465 kDa

MLNMSSDQEPPCSPTGTASSMSHVSDSDSDSPLSPAGSEGRGSHRPPGISKRDGEEPMDERFPACIRDAVSQVLKGYDWSLVPMPVRGSGGLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSENEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKAGQSDSDSGAELGHHPGSQMYKSDSGMGSMGENHLHSEHAGQNHGPPTPPTTPKTDLHHGGKQELKHEGRRMMDNGRQNIDFSNVDINELSSEVISNIEAFDVHEFDQYLPLNGHGAIPADHGQNTTAAPYGPSYPHAAGATPAPVWSHKSSSTSSSSSIESGQQRPHIKTEQLSPSHYNDQSQGSPTHSDYNTYSAQACATTVSSATVPTAFPSSQCDYTDLPSSNYYNPYSGYPSSLYQYPYFHSSRRPYATPILNSLSIPPSHSPTSNWDQPVYTTLTRP

SOX8

Transcription factor SOX-8

446 amino acids

May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3' (By similarity).

47.314 kDa

MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGARGDPAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGHSDSDSGAELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQYLPLGGPAPPEPGQAYGGAYFHAGASPVWAHKSAPSASASPTETGPPRPHIKTEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYAPGLYQYPCFHSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP