Protein
Kinetochore protein Sos7
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Function
Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Essential for chromosome segregation and bipolar sister chromatid association. Required for kinetochore targeting of MIND, but not Ndc80 complex components.
Sequence
MDQNKSTQATGNGKKTEEINELLESFIKEGPKLLWGSTNLKYEDQISRSSEHELQQYRELFTRLKFSYIEQGTKERYLRAILDDPPMLVEAEDNEKLETTNSSLKGRLKSEKREVDLLTEELKTTSRELSSNYESVMEECKNTKSTLSKLESLESELLKLQQDSSTKTPILPEVEAAIHDLESELNITNESIETIDGKIDNDEKYFIQLTKNLSLLEKEYKIASERSNQIKAAIHTRTPDADAKKQVQNWYTSMLEIYDQLLQK