sol1

Prosolanapyrone synthase

2641 amino acids

Prosolanapyrone synthase; part of the gene cluster that mediates the biosynthesis of the phytotoxin solanapyrone, a causal agent of early blight disease of potato and tomato (PubMed:20486243). The prosolanapyrone synthase sol1 is a polyketide synthase that produces the octaketide desmethylprosolanapyrone I via sequential condensations of 7 malonyl-CoA units with one acetyl-CoA unit, and one methylation step (PubMed:20486243). The octaketide backbone is further methylated by the sol2 O-methyltransferase to yield prosolanapyrone I (PubMed:20486243). Prosolanapyrone I is hydroxylated to prosolanapyrone II by the cytochrome P450 monooxygenase sol6 (PubMed:20486243). The solanapyrone synthase sol5 then catalyzes the oxidation of prosolanapyrone II and the subsequent Diels Alder cycloisomerization of the product prosolanapyrone III to solanapyrones A and D (PubMed:9659400, PubMed:18256508). Solanapyrones A and D are then converted into solanapyrones B and E, respectively, by the sol3 dehydrogenase (PubMed:20486243).

286.573 kDa

MTSQYGTNGASADPEPIAIVGMGCRWPGGVRDASSLWELLKNKRSGYREFGDHRFSRKGFHHPNSEHPGTVATEGGFLLAEDPRLFDHAFFGIGSLEVETMDPSQRKLLEVVYEAFENSGEPWDSFSGSTTGVFVGNFSSDHLIIQGRDTDHPRPYASVGTGTSILSNRVNYIFNLRGPSVTIDTACSSSMYALHLAISAIRNGDCDSAIVAASNTIIDPSTXLMMTKLGVLSPTSTSHTFDSSADGYARGEGFSALYLKRMSTAVDGDYPIRALVRGSALNANGRTGGITHPGREGQEAVIRKAYENAGNLPMKDTTFFECHGTGTPVGDPIEISAIGNVFGSATTPEKPLLVGSIKTNIGHTEPASAIAGIMKVVLALENGFIPPSIGIKKLNPKLDLKGGRINILTENTPWPDGRVRRASVNSFGYGGANGHCIIDDVRTVLPDYKKRTANTSIGHINGHTNGHTNGHTNGHTNGHTNGHTNGHTNGAHASDGHNGHHQNGMNGNSASHMSEKADKVHYPFSYKPTLVKDFNAKPRRRVLIPFSAHNEASLDLNITAISEAIKRENLADVAYTLAAKRSRFMQRTFRIVDSESPANGFAVKEKVLASGTQTARLGFVFTGQGAQWHAMGADLFEYAVFRTSIEYLDSILASLPTPSAWKIEDILAGNCDPNDIHKPEVSQTVCTAVQIGLVDLLYTWNVRPSAAVGHSSGEIAATYAAGRITAAQAIAAAYFRGQAVSKNKSKGLMLAVGLGLDKAEAYISGLDSSVRIAAINSPDSVTLSGDESTIKDVAAKLNEDKVFNRELKTGGNAYHSHHMLALGEFYNSTLSEGLDYVKSLGQAEPSQLYATRPWMSSVYPSKSTENPPVSPSYWRANLESPVRFSEALANMLNLPDPIDVLVEIGPHPALKGPVGQISRSVDKSLPYFPTLNRGTNGGISLLQLAGSLFSLNAEVDLTAVNAVDVISANQLKLVHGTTATNLPPYQYAYGPVIYHESRFSKEFRGRDIVRHDLLGSKLPGNAKLRPQWRNILRLKDLPWLNDHKLLPYPVFPAAGYIATVIEAASRIYNEQSEPLDITGYKLRNVTFSSAMRLPDDDFGLEIITSLELADAANPKAPTWATFSISSVAREAGTWTEHCSGRVRVIAGTSVANEKMSTEMDARTLDTKAWYKKFAEIGLGYGPTFQPLSNIRADPSKGLAVAQLALHTTRDTVEGGESNYPLHPASLDAVFQLSLVASHGGQIDRVCNAFVPVHIDQLYVRNGVSQDSAVAIALGSMKGLRSAHAKLQVLDKSEQVVLDVGNLRCVTYTEVLPSTGADKEAFSIPFLRLSWKPDIRAMDNEQVQRRFPPPTENVEKAYLFDKLERLGTLYVAEIHERYAGQGQFSSAPAHIDNFLSWVRRRMKDDNKWVAEANSLTSSQRGILIKELFAEVGHISDVKIANKVFNNMEDILNERKTGLEVVIPDNLLHGMYEDGLIMTGAYPQLVRFFDLFGYANPNMRILEIGAGTGGATRKILKTLIGPHGIKRYQDYTFTDISSGFLAQAREAFADFQDMKYSVLDIQENPLEHGYEAVYDVVVACECLHATPSIVKTLTNCRKLVKPGGRLVVVENTRAVIGHGLVLGHLSGYWDGIPDGRVESPFLHLEGWNASLNQTGFAGAELVLDDYPAPYTTARTIVSSAVEEPAKVGQSPNGTVHLVHGDNRPELLSRIEHELTERGTEFKVISIGDVETHLPDNSRTVAFADSKSLLVNASENDLKSFKALIRKSANLVWVTFGGIVHGHDPDASITTGLLRTLGTENPASQFLSIDVSPDSDFQEIRLTRTILDQELALSDRIAGESRDYEFVWQEDCLWVSRLVPDVALQDKLELSESRPSRAEMLPLDSQGSVQAAFETPGLLTSLYFKPYEETWKSLPDDWIQVKVAAVGLNWKDLLTSAGRFDMNTFSSEYSGVVAQVGLNVTNVAVGDRVYGYGRGHFGNYVRAPANFAYRMLPGEDFVKMATIPLVGMTAIYSFECVTQLKDQERLLIQSATGGLGLSAIQLAKAKGAEIFATAGTQEKRRYLIDVVGIPASHVFSSRDPADFAKLMEATDGKGFNVILSTSSGELLYDSIKMLAPMGRIIDVGRIDVQNSTSLALELFKRNATFTSFDLAVADDADRALGPALMKAVNKRVRAGQMGPLSSITTYDVSQLDQALMAFSKGTHVGKLVVTFQNPDALVKMVPAAPHAQFARNANYLITGGLGGLGRSIVNFMAERGARHFTVLSRSRKINSEGQMLIDKLATSGTVVECVSCDVSDSKDVARAVQDAAVVRPIKGIVHAAVSYQDLSFDKLAIEQWTSALAAKVQGTKNLHEATKTHALDFFLMTTTIESFVALATQSAYTAANNFQDYFARWRRQQGLPASTVSFGLIRDVGHLSTNSTTLALMARNKVMDISEYNFLRLLEPAFLNNESALDPAASKEPYTGAVDDPLSVTNVVTCFDPATMATRKREEAAENNGNTGNSPRWYTDARVSLIMRAFDDAERYQASAGGGGDGGNERGNNAGVASLRSEFGEAVKAGPAERSRTVALVTDAIVKTVAQMLFVDASGVDASRTVADYGVDSLIAAELRNWFNVAFGADVSMLEMLDTATSMKILANKIVDGALA

sol1

SWI/SNF chromatin-remodeling complex subunit sol1

865 amino acids

Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.

Belongs to the SWI1 family.

96.018 kDa

MNNQGFVPASDYPTAVSYPTQGQSYNTQEEQPAYPQRFSTSQGMYAAEYGNANMMNTSENEPNNLAHSQPFRQSPSTQRNLPNQSFDFASNGAWNGSGSVKYSSPMMPSSRIPFQQEKEAAMQQQQQQQQQQQLYQRQMQSREALLSQQIPPNQIGINAHPAVRQTPQPAPSPNTPSGNANQLTPAYAASFDKFMVSLISFMEKRGTPIKSYPQINNTPINLMMLYALVMRAGGSRQVSAHNFWPKISASLGFPSPDAISLLIQYYNSYLLPYEEAWLAAQQQQKSLQQAKANHSANVQSRPKNYPQKPVQTTPEAVHANGSMHGSLHSKSPSPAFTANRFSPAAPTTVSSERNAPPYPSAPTRPTPPTVQTSSSAAPVDSAEPVAYQPIKKPIDPMLGYPLNVAATYRLDESLLRLQMPSIVDLGTVNIQALCMSLQSTLEKEITYAMNVLLILTNDQKWMFPLSECQDVVDALIDVATQCLDNLLSVLPNEDLMEIADKRPSYRQLLYNCCVEISQFSREDFSNSLSENKTKDSINAIDVHNSEQNLLAVFVIFRNLSHFEANQNVLVQNPDFFPLLIRVVKSLNFHATSLLRSSRNTLDLHKDVLIVLCQLSQNFILPNVDVARHVLLFILSFSPFNRKKSKTILNDTLPTSIPSYTPATHPYAGPAINAYAKLLAKDANNKTNFQAIFDNNPKFLDSLFLLLASVVPKFNRHCLKICERRLPLLQQSFFCLAATVSYVKQSEQAANWCNIGEGFFVSMLRLLILLSGHPSLNPPSRVASQYPTTNPFRYVIQSGISTVRRLLSLVEAGNISLSSFPKSETLLAVLLAPTTETSFLKEISNLLDRTGDSDASLENTDDKSGI

SOL1

Carboxypeptidase SOL1

491 amino acids

Possesses in vitro carboxypeptidase activity against the C-terminal arginine and lysine residues. Involved in the maturation of CLE19. Removes the C-terminal arginine residue of CLE19 proprotein. The cleavage of the C-terminal arginine residue is necessary for CLE19 activity in vivo. Is not involved in generating active CLV3 (PubMed:24118638). Is not involved in CLE19 or CLV3 perception (PubMed:12932329, PubMed:24118638).

Belongs to the peptidase M14 family.

56.046 kDa

MSKLRFFQSLLISTVICFFLPSINARGGHSDHIHPGDGNYSFHGIVRHLFAQEEPTPSLELTRGYMTNDDLEKAMKDFTKRCSKISRLYSIGKSVNGFPLWVIEISDRPGEIEAEPAFKYIGNVHGDEPVGRELLLRLANWICDNYKKDPLAQMIVENVHLHIMPSLNPDGFSIRKRNNANNVDLNRDFPDQFFPFNDDLNLRQPETKAIMTWLRDIRFTASATLHGGALVANFPWDGTEDKRKYYYACPDDETFRFLARIYSKSHRNMSLSKEFEEGITNGASWYPIYGGMQDWNYIYGGCFELTLEISDNKWPKASELSTIWDYNRKSMLNLVASLVKTGVHGRIFSLDKGKPLPGLVVVKGINYTVKAHQTYADYHRLLVPGQKYEVTASSPGYKSKTTTVWLGENAVTADFILIPETSSRGNQLRSSCDCSCKSCGQPLLTQFFTETNNGITLTLFVVVVFLCFLLQRRVRFNLWKQRQSSRRSITV

SOL1

6-phosphogluconolactonase-like protein 1

321 amino acids

May be involved in regulation of tRNA subcellular distribution.

Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

35.653 kDa

MTTTVPKVFAFHEFAGVAEAVADHVIHAQNSALKKGKVSRSTQMSGTSLNGNGNTESKTMERVNSVRSNASSRGGSEDGATKKLKKEKERRFKIALSGGSLIQVLHEGLLKRDDVQWGKWDIYFADERLVPFSSSESNYGLAKRKIFDLIDTEKYGTPKIYHIDESLINDPQECADNYEKILIKGFAGRDSVKLPMFDLFLLGCAPDGHIASLFPNFQENLRENLAWVIPVENAPSGPSNRISLTIPVICHSHRVTFVVEGATKAPVIKTIMERPEKGLPSSIVNEGAAGRVSWFVDDDALKDVFVIKKKYKFYDDENLTE