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snrpC

Gene
snrpC
Protein
U1 small nuclear ribonucleoprotein C
Organism
Dictyostelium discoideum
Length
174 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
20.657 kDa
Sequence
MPKYYCDYCDKYLTHDSPSVRKSHTVGKQHKLAVQLFYQQFEAEFTQSLIEARLKEYEESKGRLIHQPPMGIIPTPYGQMYQQQQQQQQQQGILPFQGMQPPPHQQQGMVLSPGMPIHKMQPHQFNNNNNPHQQHSFQPPHHQHHPHQQHQQHQQHQHQHQHQQQHNQPTIPGL
Protein
U1 small nuclear ribonucleoprotein C: snrpC

Gene
Snrpc
Protein
U1 small nuclear ribonucleoprotein C
Organism
Rattus norvegicus
Length
159 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
17.364 kDa
Sequence
MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPAPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR
Protein
U1 small nuclear ribonucleoprotein C: Snrpc

Gene
snrpc
Protein
U1 small nuclear ribonucleoprotein C
Organism
Xenopus laevis
Length
159 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
17.373 kDa
Sequence
MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPTPFAAPPAGSAMIPPPPSLGGPPRPGMMPAPPMAGPPMMPMMGPPPPGMMPVGHGPGMRPPMGAHMPMMPGPPMMRPPTRPMMLQSRPGMARPDR
Protein
U1 small nuclear ribonucleoprotein C: snrpc

Gene
snrpc
Protein
U1 small nuclear ribonucleoprotein C
Organism
Xenopus tropicalis
Length
159 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
17.391 kDa
Sequence
MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPTPFAAPPAGSAMIPPPPSMGGPPRPGMMPAPPMAGPPMMPMMGPPPPGMMPVGHGPGMRPPMGAHMPMMPGPPMMRPPTRPMMLQSRPGMARPDR
Protein
U1 small nuclear ribonucleoprotein C: snrpc

Gene
SNRPC
Protein
U1 small nuclear ribonucleoprotein C
Organism
Bos taurus
Length
159 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
17.394 kDa
Sequence
MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPTPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR
Protein
U1 small nuclear ribonucleoprotein C: SNRPC

Gene
SNRPC
Protein
U1 small nuclear ribonucleoprotein C
Organism
Canis lupus familiaris
Length
159 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
17.394 kDa
Sequence
MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPTPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR
Protein
U1 small nuclear ribonucleoprotein C: SNRPC

Gene
SNRPC
Protein
U1 small nuclear ribonucleoprotein C
Organism
Gallus gallus
Length
159 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
17.396 kDa
Sequence
MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPTPFSAPPPGGAMIPPPPSIPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPSRPMMVPTRPGMTRPDR
Protein
U1 small nuclear ribonucleoprotein C: SNRPC

Gene
snrpc
Protein
U1 small nuclear ribonucleoprotein C
Organism
Danio rerio
Length
159 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
17.286 kDa
Sequence
MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPTPFPGAPPPGGSLLPHPSIGGPPRPGMLPAPPMGGPPMMPMMGPPPHAMMPGGPGPGMRPPMGGPMQMMPGPHMMRPPARPMMPAVRPGMVRPDR
Protein
U1 small nuclear ribonucleoprotein C: snrpc

Gene
SNRPC
Protein
U1 small nuclear ribonucleoprotein C
Organism
Homo sapiens
Length
159 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
17.394 kDa
Sequence
MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPTPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR
Protein
U1 small nuclear ribonucleoprotein C: SNRPC

Gene
SNRPC
Protein
U1 small nuclear ribonucleoprotein C
Organism
Macaca mulatta
Length
159 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
17.394 kDa
Sequence
MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPTPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR
Protein
U1 small nuclear ribonucleoprotein C: SNRPC

Gene
Snrpc
Protein
U1 small nuclear ribonucleoprotein C
Organism
Mus musculus
Length
159 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
17.364 kDa
Sequence
MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPAPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR
Protein
U1 small nuclear ribonucleoprotein C: Snrpc

Gene
snrpC
Protein
U1 small nuclear ribonucleoprotein C
Organism
Polysphondylium pallidum (strain ATCC 26659 / Pp 5 / PN500)
Length
141 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
16.03 kDa
Sequence
MPKYYCEYCDKYLTHDSPSVRKSHTIGKVHQQAVTLYYKQFEAEWFKSQMQQKGGQVPMMPPFGMQPGLLPPNMVPGQFNIPMMPPGQFPFPPPPGQPMGGMPPHQQQPMSFNPHHPYPPPHLQQSAQQFNSNSPPSNNDQ
Protein
U1 small nuclear ribonucleoprotein C: snrpC

Gene
SNRPC
Protein
U1 small nuclear ribonucleoprotein C
Organism
Monodelphis domestica
Length
138 amino acids
Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Similarity
Belongs to the U1 small nuclear ribonucleoprotein C family.
Mass
15.559 kDa
Sequence
MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVRDYYQKWMEEQAQSLIDKTTTAFQQGRIPPNLFSAPPLGGPMIPPPHPSMMGPPPPGMMPVGPPPGMRMPMGGHMPMMPGPPMMRPLPHPMMVPTRPVMPRPDR
Protein
U1 small nuclear ribonucleoprotein C: SNRPC