Protein
Pristinamycin IIA synthase subunit A
Organism
Streptomyces pristinaespiralis
Function
Catalyzes the oxidation of the proline residue of pristinamycin IIB (PIIB) to pristinamycin IIA (PIIA).
Similarity
Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family.
Sequence
MTAPRRRITLAGIIDGPGGHVAAWRHPATKADAQLDFEFHRDNARTLERGLFDAVFIADIVAVWGTRLDSLCRTSRTEHFEPLTLLAAYAAVTEHIGLCATATTTYNEPAHIAARFASLDHLSGGRAGWNVVTSAAPWESANFGFPEHLEHGKRYERAEEFIDVVKKLWDSDGRPVDHRGTHFEAPGPLGIARPPQGRPVIIQAGSSPVGREFAARHAEVIFTRHNRLSDAQDFYGDLKARVARHGRDPEKVLVWPTLAPIVAATDTEAKQRLQELQDLTHDHVALRTLQDHLGDVDLSAYPIDGPVPDIPYTNQSQSTTERLIGLARRENLSIRELALRLMGDIVVGTPEQLADHMESWFTGRGADGFNIDFPYLPGSADDFVDHVVPELQRRGLYRSGYEGTTLRANLGIDAPRKAGAAA