snRNP-U1-70K

Gene

snRNP-U1-70K

Protein

U1 small nuclear ribonucleoprotein 70 kDa

Organism

Drosophila melanogaster

Length

448 amino acids

Function

Mediates the splicing of pre-mRNA by binding to the stem loop I region of U1-snRNA (PubMed:15611175). Required during oogenesis for nurse cell chromatin dispersal (PubMed:24244416).

Mass

52.901 kDa

Sequence

MTQYLPPNLLALFAAREPIPFMPPVDKLPHEKKSRGYLGVAKFMADFEDPKDTPLPKTVETRQERLERRRREKAEQVAYKLEREIALWDPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLEREREDREGPGRGGGSNGLDARPGRGFGAERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDREREKKKKRSKSRERESSRERRERKRERRDRERGTGSGGDVKERKPDFRDMDVIKIKEEPVDDGYPTFDYQNATIKREIDDEDEEKYRPPPAHHNMFSVPPPPILGRGNASTNPNPDNGQQSSGDPSWWRQ

Protein

U1 small nuclear ribonucleoprotein 70 kDa: snRNP-U1-70K