Protein
Carbapenem-hydrolyzing beta-lactamase transcriptional activator
Organism
Serratia marcescens
Function
This protein is a positive regulator of gene expression of carbapenem-hydrolyzing beta-lactamase (smeA). Seems to also be a repressor of its own transcription.
Similarity
Belongs to the LysR transcriptional regulatory family.
Sequence
MKNRIPLNALRAFEASARYLNFTKAGLELHVSQAAVSQHVRTLEAILGVNLFKRLPRGLQLTEEGLHLLPMINEAFSIMGSALERFHEGKIREVITVAVVGTFAVGWLLPRLSGFTKSYPWIDIRVITHNNVINLAAEGIDAAIRFGHGFWQSTENYKLFSAPHTVLCPPNVAKKLTTPEDMKDYRLLRTYRKEEWSSWFKAANLKPWPVTGPIFDSSRHMDDAAKICGDIALAPYKMFIHEIENGSLVKPFDIEVHLGGYWLTILKSRSNIELNNALNIFKTWLLNASHSI