Protein
Structural maintenance of chromosomes-like protein 1
Organism
Caenorhabditis elegans
Function
Acts as a modulator of condensin function, possibly by binding to the condensin SMC subunits and thereby inhibiting their function. Negatively regulates the condensin I complex in mitotic chromosome segregation. Negatively regulates the condensin I-like dosage compensation complex, which functions in the regulation of X chromosome-linked gene transcription, by limiting the association of the complex with the X chromosomes.
Similarity
Belongs to the SMC family.
Sequence
MTYPQQRLLTVDILNFKCYQHHKSFGPFDHVTTFIGMNGCGKSIMIEAIAFVFGEDLPDPKNPHNEHLFYDYNIRCVVSLKFEMPDGSTKRFTRIGLKTTYTYMIFNKYVTEEEYLLELGKMNFRFAGQNISVYNKTTLKVTRKSAEELGAFFDIVSNSIEFKPEYDELKAKLNFAESTVLRWAKMIDSIELEKEKFITLTLYKLYLCDKEIQETKEKFVAEQLKVNAKNAKMPLRISRYSEAIPKQTPSPNFKNNAIVVRPKTHNHYDNLITVDKLNSYLNEKVTERRELLQFAVNHPNMNIRFSEEGPNIYAREIDYTELPEYYKKESDDIIATSYKRSMLEKEIKKIRQCWLDENNIKDDANIDNINMRIKEATTKHTLALNIESEARLNWEKLRVMRSARFNNFMAPLQTSLSRIYAEIAQDEDSLAFLRPLDEEEPYLAIDAFVKERHSEHISTRTFHGGSRMIVDLALIFAIHEWKPSPLVVIDDIDRNLYHEASKKIEPYLSRQKQTQFIVTTKEDSYFTEVTKTITLEN