Protein
Vesicular glutamate transporter 2.1
Function
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. Required for glutamate release by retinotectal synapses and visual acuity.
Similarity
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
Sequence
METPREPAGFSKEGLKQLAGKTLGHVYRVIEKRQKPGENIELTEDGRPAQINERKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTIHLNGKIIIKEKAKFNWDPETVGLIHGSFFWGYIVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIPSAARGHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGCFGIFWYMFWILVSYESPAEHPTITAEERCYIEESIGESAKLLGPADKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSALPHLVMTIIVPIGGQLADHLRSKNILSTTTVRKIMNCGGFGMEATLLLIVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQYVFLIASLVHYGGVIFYGIFASGEKQPWADPELTSDEKCGFIDEDELAEETGDITQSYGALGAPAKSYGATTQLNGGWAEGWDKREEYVQDGVEEGGYGYRQGGNYS