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sigI

Gene
sigI
Protein
Probable ECF RNA polymerase sigma factor SigI
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
290 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor until released, although no anti-sigma factor is known for this protein (By similarity).
Similarity
Belongs to the sigma-70 factor family. ECF subfamily.
Mass
31.431 kDa
Sequence
MSQHDPVSAAWRAHRAYLVDLAFRMVGDIGVAEDMVQEAFSRLLRAPVGDIDDERGWLIVVTSRLCLDHIKSASTRRERPQDIAAWHDGDASVSSVDPADRVTLDDEVRLALLIMLERLGPAERVVFVLHEIFGLPYQQIATTIGSQASTCRQLAHRARRKINESRIAASVEPAQHRVVTRAFIEACSNGDLDTLLEVLDPGVAGEIDARKGVVVVGADRVGPTILRHWSHPATVLVAQPVCGQPAVLAFVNRALAGVLALSIEAGKITKIHVLVQPSTLDPLRAELGGG

Gene
sigI
Protein
Probable ECF RNA polymerase sigma factor SigI
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
290 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor until released, although no anti-sigma factor is known for this protein (By similarity).
Similarity
Belongs to the sigma-70 factor family. ECF subfamily.
Mass
31.431 kDa
Sequence
MSQHDPVSAAWRAHRAYLVDLAFRMVGDIGVAEDMVQEAFSRLLRAPVGDIDDERGWLIVVTSRLCLDHIKSASTRRERPQDIAAWHDGDASVSSVDPADRVTLDDEVRLALLIMLERLGPAERVVFVLHEIFGLPYQQIATTIGSQASTCRQLAHRARRKINESRIAASVEPAQHRVVTRAFIEACSNGDLDTLLEVLDPGVAGEIDARKGVVVVGADRVGPTILRHWSHPATVLVAQPVCGQPAVLAFVNRALAGVLALSIEAGKITKIHVLVQPSTLDPLRAELGGG

Gene
sigI
Protein
RNA polymerase sigma factor SigI
Organism
Bacillus subtilis (strain 168)
Length
251 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of cell wall metabolism in response to heat stress. Acts by regulating the expression of genes such as bcrC, mreBH and lytE (PubMed:18156261, PubMed:21541672, PubMed:23199363). Also plays a role in survival at low temperatures (PubMed:19114499).
Similarity
Belongs to the sigma-70 factor family. SigI subfamily.
Mass
29.193 kDa
Sequence
MKPVLSLLFKLGKKKQTLEKAVESIQKGNKDLQNELIQQYKPFIAKTVSSVCKRYIDEKDDEFSIGLIAFNEAIEKYSPEKGNSLLAFAELIIKRKVIDYIRKEARSAQNINIDLQEGDDQESSQSLIEAELSIDEYRRQIEQEQRREEILYFQKQLKDYGLSFKELLENSPKHTDARQNAIKVAMTLVEHEELAAILYTKKQLPVKQLEQLVSVSRKTIERNRKYIIAMCIIITGDYIYLKDYLKGVLHS

Gene
sigI
Protein
RNA polymerase sigma factor SigI
Organism
Bacillus anthracis
Length
240 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor contributes to both stress response and virulence gene expression.
Similarity
Belongs to the sigma-70 factor family. SigI subfamily.
Mass
28.822 kDa
Sequence
MLSLVMKILRKPKIEDIVCNIQNNEEDKEAFIVQYQPFIRKSISSVCRRYITEQDDEYSIGLFAFNEAIEQYSYKKGKSFLAFADLLIKRDVIDYIRKESKHNLVFLKEDEQEEMLEMQVSLTEYMKEIENGNRKEEILHFQSVLADFKITFSELAKESPKHRDTREHLIEIVKVIIKEEEMMEELFRKKKLPLKHIEPRVRVSRKTLERHRKYIIAMCIIFANNYTYILDYIRGGKHDE