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sigH

Gene
sigH
Protein
RNA polymerase sigma-H factor
Organism
Bacillus licheniformis
Length
223 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation.
Similarity
Belongs to the sigma-70 factor family.
Mass
26.109 kDa
Sequence
MNLQNNQGKFSKEQFSKERFCQLEDEQVIEMVHVGDSDALDYLITKYRNFVRAKARSYFLIGADREDIVQEGMIGLYKSIRDFREDKLTSFKAFAELCITRQIITAIKTATRQKHIPLNSYVSLDKPIYDEESDRTLLDVISGAKVMNPEELIINQEEFDDIELKMGELLSDLERKVLALYLDGRSYQEISEELNRHVKSIDNALQRVKRKLEKYLELREISL

Gene
sigH
Protein
RNA polymerase sigma-H factor
Organism
Bacillus subtilis (strain 168)
Length
218 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation. It is also required for transcription of several stationary phase genes.
Similarity
Belongs to the sigma-70 factor family.
Mass
25.447 kDa
Sequence
MNLQNNKGKFNKEQFCQLEDEQVIEKVHVGDSDALDYLITKYRNFVRAKARSYFLIGADREDIVQEGMIGLYKSIRDFKEDKLTSFKAFAELCITRQIITAIKTATRQKHIPLNSYASLDKPIFDEESDRTLLDVISGAKTLNPEEMIINQEEFDDIEMKMGELLSDLERKVLVLYLDGRSYQEISDELNRHVKSIDNALQRVKRKLEKYLEIREISL

Gene
sigH
Protein
ECF RNA polymerase sigma factor SigH
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Length
216 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RshA) until released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing in the extracytoplasmic compartment (By similarity).
Similarity
Belongs to the sigma-70 factor family. ECF subfamily.
Mass
24.225 kDa
Sequence
MADIDGVTGSAGLQPGPSEETDEELTARFERDAIPLLDQLYGGALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTYINSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTEIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQLRGLLADVARDRGFARGEQAHEGVSS

Gene
sigH
Protein
ECF RNA polymerase sigma factor SigH
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
216 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RshA) until released. This sigma factor is involved in heat shock and oxidative stress responses; it positively regulates the expression of itself, sigE, sigB and a number of transcriptional regulators as well as other effectors of heat and oxidative stress, leading to direct and indirect control of up to 25% of the bacterial genome. Modulates expression of host genes for intercrine beta (chemokine CC) and apoptosis, altering the host immune response.
Similarity
Belongs to the sigma-70 factor family. ECF subfamily.
Mass
24.225 kDa
Sequence
MADIDGVTGSAGLQPGPSEETDEELTARFERDAIPLLDQLYGGALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTYINSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTEIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQLRGLLADVARDRGFARGEQAHEGVSS

Gene
sigH
Protein
ECF RNA polymerase sigma factor SigH
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
216 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RshA) until released. This sigma factor is involved in heat shock and oxidative stress responses; it positively regulates the expression of itself, sigE, sigB and a number of transcriptional regulators as well as other effectors of heat and oxidative stress, leading to direct and indirect control of up to 25% of the bacterial genome. Modulates expression of host genes for intercrine beta (chemokine CC) and apoptosis, altering the host immune response.
Similarity
Belongs to the sigma-70 factor family. ECF subfamily.
Mass
24.225 kDa
Sequence
MADIDGVTGSAGLQPGPSEETDEELTARFERDAIPLLDQLYGGALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTYINSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTEIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQLRGLLADVARDRGFARGEQAHEGVSS

Gene
sigH
Protein
ECF RNA polymerase sigma factor SigH
Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length
215 amino acids
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released. This sigma factor is involved in heat shock and oxidative stress responses.
Similarity
Belongs to the sigma-70 factor family. ECF subfamily.
Mass
24.5 kDa
Sequence
MTDVDRVEPETPPEREETDAELTARFERDAIPLLDQLYGGALRMTRNPADAEDLLQETMVKAYAGFRSFREGTNLKAWLYRILTNTYINSYRKKQRQPSEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALPDTEIKAALQALPEEFRMAVYYADVEGFPYKEIAEIMETPIGTVMSRLHRGRRQLRDLLAGVARDRGFIRGPQLGEPEEVTS