Protein
Phosphatidylinositol transfer protein sfh-5
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane (By similarity).
Similarity
Belongs to the SFH5 family.
Sequence
MSTQPSDSAEPGAAPAAVSTYAGVENTPTVPGSEPDAAKHAEEEPKVVNPTEPQPTAPVDNEPKPAAAPAQEADSPADIKDSVSTTAGELSPLAQLWKAAEGHAHFEIWGVPLSDPERHIPTQIIFQKFLNANEGQVEKAKDQLLKTLDWRQKTQPQQLLRKMFSKAKFDGLGYVTTYTAGDEPAVDEPEQKEVFTWNLYGSVKSLDETFGNLQEFVEWRVALMELGLMEINIGGAIKPITADYDPYKMTQVHDYKGISFLRQTDVAKAASKECIKVLGDNYPELLKEKFFLNIPAIMGFFYGLMKMFVSKKTLNKFHPMSSGTNLAKEFVNTKVDGLGDKLPAEYGGKGADLKTLGKAPIVT