set9

Gene

SET9

Protein

Histone-lysine N-methyltransferase SET9

Organism

Yarrowia lipolytica (strain CLIB 122 / E 150)

Length

866 amino acids

Function

Histone methyltransferase that specifically methylates 'Lys-20' of histone H4.

Similarity

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.

Mass

96.798 kDa

Sequence

MITVTPGELATIDDALTDLLLERVFYWAEVRKASVHYKPLRGISDRHIHDLVRSIAACETGAAANLAVKKATNAFLELKEVRGYRGRLSPLAYEEFQRHTVRYLTIYKASCGFEINVSMRYKCRSNRGESCVISRVRYNRGDEIVGLSGCLAKMTKDEELALANDFSVLHSSRRGGNCLMLGPARFVNHDCSANARFVPVPSGMVIQAVKPINVGDEITVKYAENYFGRRNKECLCQTCEENSRGLYGSPQESSEEESDDDMDELTKIELQRRKKRQEQREGGTPELREGGRGSSESSRETSEEAIEISTSKNWPLIPKIESHTADSTPLPVPVGEVSEATVTEVSTVVPAQEAIPVNESTTALSQSSNEFQDPTIDPILNGASAEIRFPSLPSPDTTTSPESQVPPFIQPKSARRNHHYLGMHNTDERVRFNDRLSVLDERGGSEDMESCLVSGSESRDDSTAMSRDEESSRDDGDGSRSKRSKRHVRAQRKNSGSWSFSQEDLSFDRLCKAAREQAYDPSRYALTGVYGFSVSGATQTCVSCCSVYNLTDGPKTLGHFCPRCHRHAAIHSFAWPYTNHKHALPLCLLMMRPPKKLEDEDWGLSKPQVAQQFGAKNRKIFEEDGSLVQKKRKSLAWSWEYTKEEPAQEITSMRIEDMSPKELKKWSQAGRQTRSGRVSMLPEKPKRSRKSAPEPVEMRDNVAQLSREERAWKRARRGTVGHEKVEVNTPTVETPSTGTPKVKKLHWKQKLAMERRQKEAEAAEVAETRVADGVDASTPSPAGSTPTPRGRGRPRKSSREEEIPPEKTPEAKRPSPAATKTPSMSPKVKKEPLSMSFSMSPTSRSGRVRNPTEKALQLMEQGEYVI

Protein

Histone-lysine N-methyltransferase SET9: SET9

Gene

SET9

Protein

Histone-lysine N-methyltransferase SET9

Organism

Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)

Length

734 amino acids

Function

Histone methyltransferase that specifically methylates 'Lys-20' of histone H4.

Similarity

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.

Mass

81.046 kDa

Sequence

MPRAPTSAIKKQPLTFAQLAAYDDILTDALIDHVYYWTAIPKNRPLYHPSRGIREEEITKIIQTHLIVDPDLAIAEEKLLATDGLRKFHNSLRTDKEKEDFKAHLRRYISIYLPDCPFEVNATNRFTIDSYEASITARRPIRRNEAIKYLAGTQVTVTPEEEAQLALRKKDFSLVVSSRSKLTSLFMGPARFANHDCAANARLVTRGSAGIEIFACRDIGLGEEITVTYSESYFGENNCDCLCQTCEDNVANGWKPKDGTVPVHRSIEESVLGDDQGYSLRRRRRERSVSVAGSRTSSVTPDIRPRIFKTAKNRAMASDRASTTDSDGIDVVAMAVAAPKRNFDTTALSSPPLTPAKRQKPNHYDVVPLPLGLDVSRDSSASGPVDSLIATEDEKSTATQATTPEFEEPKPPSMREKPLLSPEMSPMKEGATPVGALNGERDEPTETGAPLSVLPTTETDLPEETLDIAATTPSLFPSSECSMTANDLPEHITPVSEPPRLTQEGKSVARQDSQETIIEESLAVPNSAPSQIQEAENNAQQGAETPVLGASSLTAEPHNEVAPVISAVSTKKKKRRVSEKPAPEPVRKQRVPGDYTLTPLLLAQPETAWIHCTNCNTAFVQSDAYYTRANCSRCERHSKLYGYVWPKTAPAGKNDREERVLDHRLINRFLHPDDEAIIRGRKPWRERLGQSSSSLAPSEERGRQRESGTPQGTPGDNYRRSGRARRASAKAMAQ

Protein

Histone-lysine N-methyltransferase SET9: SET9

Gene

SET9

Protein

Histone-lysine N-methyltransferase SET9

Organism

Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)

Length

662 amino acids

Function

Histone methyltransferase that specifically methylates 'Lys-20' of histone H4.

Similarity

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.

Mass

74.1 kDa

Sequence

MAPSQTANKKPRMTLAQVSAYDDILTDALVDHVFYWTTVPKNRTSYHPSRGVKEEEISKILQEEVVLKKDLDSAEKRLLTTNGLKRFHNGLKTDKEKDDFRKHLRRYVQIYLPDCPWEVSSTNRYTIVSHEAAVTARRAIRRNEAIKYLSGVQVVITPEEEMAISSQKKDFSIVVSSRSKCTSLFMGPARFANHDCDANAKLMRTSHAGIEIVATRPIDAGEEITVTYGDNYFGENNCECLCKTCEDLLRNAWEPEEGTVPVQTGIGQSLSDGYSLRRRRRDDSISGSSRTPSVTPDMRPRITKANSRGSLLARDTSSVRSPSIDQTSRKRTHDVLATPPKTPAKRQKLGVQPIVSDSSSRGTSVTASESSGAVETDVTSPEKETPEPMQTPLKGASKKQNNEQSRLAPVSPQSTEGSRSPQQKNGALSSNRSSLDTMSIQAILNDPLESEVESEPESKMKKVTVVPPPVEPVAPIATSIEAVEEGQAADAEQSKRKKQPRRVHKEDTPPARVRTPGDYLLTPLLLSEPEMAWIQCTNCDEYFVQQNAYFTRASCPRCERHSKLYGYIWPKTDKAGPNDKEERILDHRTIHRFLDPDNERRVRNRKSFGASKTNTEEAEDVERGRKRFGTAGLMGRNASTTEDSGHRRSGRLRRVNSRFLDP

Protein

Histone-lysine N-methyltransferase SET9: SET9

Gene

SET9

Protein

Histone-lysine N-methyltransferase SET9

Organism

Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)

Length

662 amino acids

Function

Histone methyltransferase that specifically methylates 'Lys-20' of histone H4.

Similarity

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.

Mass

75.177 kDa

Sequence

MPPSKAEKRGLTLEKLASYDDVITDALVDKIYYWATIRKNRGTRFTASRGLQEEDIAGVIREQVIWDKDPVEAVQQLLDLPGLRKYMKGLRDEKDQDQFKRHLRRYVNIYMPDCPFEVTTTNRYTITDHEASITARRDINPREEIKYLTGVQVAMTEEQEKTLELARKDFSLVISSRKKTRSLFLGPARFANHDCDANARLSTKGYDGMQIVAVKPINEGDEITVSYGDDYFGDNNEECLCHTCEDRQQNGWAPMKRVEDSDDEDMEEAESPVENPSEATSSGTATSGGKRARDITEEDAGADLPPTSKRARIEKKPSPTKARASDHLREATLKKVHSTSSLRREMPVSSIEDPSANINVTSPQMTQDIRNQQRDGLLTVSLDETSSSRESTPQSPLMAASPKSSHSTDATSVDDEHHVDSLPKIKVEPEVVHENPALGVATVKEEVITTTVNAPWPSPPAEDDEMSDLSELSDSMEFDSVKQQIVKRKFRPTLRTTRSKSRYEVHNRVGTPVSSAVGQDGEWVENPRKPGDYMTSSSLLSAKFSKWVECQTCDVQFVQQDGYNTRKECPRCERHSKLYGYAWPKTEREGKHDKEERITDHRIVHRFVDPDEERELKRGKTKKILKESIRERFSTPRSGRESMSASVEVDSGRKRRRVRKTM

Protein

Histone-lysine N-methyltransferase SET9: SET9

Gene

set9

Protein

Histone-lysine N-methyltransferase set9

Organism

Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)

Length

641 amino acids

Function

Histone methyltransferase that specifically methylates 'Lys-20' of histone H4.

Similarity

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.

Mass

71.748 kDa

Sequence

MPSSKARSSPSVDRRERLTLAKLASYDDVATDALVDCAYFWTKTRKNRTKYIPVRGLAEDTVAHILLHDVIVAKDVSAAERKILDLIGMKRYLAKLPNDREKDWFRKHLRKYIQMYLPDCPFEVTTTNRYTITEHEAAICARKFIPQGQEIKYLSGTLVPMTKEEERDLDLKRKDFSIVMSSRRKTPSFFLGPARFANHDCSANGRLVTRGSEGMQVVATRDIYIGEEITVSYGEDYFGIDNCECLCLSCERVPRNGWSQNLAPGPQSKPSTPEPKASEDHLTPRKRKAQSDIDSDSSPSSTPRKRGKFTPRGSKLRSQLSLTEDIAISIESEPRVPSSNLALSAQEAGDSGKSSSAGDNVESSGTDSESLTSITPQESQRSSASTAATSVFDEAVSLNTRPTKSAVTTAAPAESSIAAEAPLSTTIPETDIKLEVEPSCEPTTTVTAQLDTTVRADSCVSDISSSTKLEDGSEALEHVKKPRKPRTKRVYLTIEPESKLNRVPGDYTKTPKLLAHSYDRWVDCHTCNAWFVQQNSYLTRRECPRCERHSMLYGFRWPKTEKEGPNDDEERVMDHRTIHRFLYPEEEALVSRRGRGVSFGLTPTPELSDMRSETPDSEALDERGNTRVTRRRTRAIRVTTV

Protein

Histone-lysine N-methyltransferase set9: set9

Gene

set9

Protein

Histone-lysine N-methyltransferase set9

Organism

Aspergillus terreus (strain NIH 2624 / FGSC A1156)

Length

629 amino acids

Function

Histone methyltransferase that specifically methylates 'Lys-20' of histone H4.

Similarity

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.

Mass

71.319 kDa

Sequence

MAPSKARSSPAVERRDRLTLAKLASYDDVATDALVDRAYFWTNTRKNRTKYIPVRGIMDDKVAEILLHHVIVAKDTVKAERELLAISGIKKYMAKLPSDREKEWFRRHLRKYIQMYLPDCPFEVTTTNRYTITEHEAAICARKFIKQGQEIKYLSGTLVPMTREEEQDLDLKRKDFSIVMSSRRKTPSFFLGPARFANHDCDANGRLVTRGSEGMQVVATRDIEIGEEITVSYGEDYFGIDNCECLCLTCERAVRNGWAPQVDSEASSTASTPALNDETKSAHGSTSPQKRKYAPDADSDASASPTPQKRRKFSRQYSKLRTEVSLSGDVTAIEPDPEQNTKIAVETTTDVPKDKPATNGVTENESNARVSENQRATSDREPSSPLGVDESQNSSASTAPTSLFDVGIKLEESTEAFTQETLTTTKAGSVADSHGDGDCRQLTAGIEQEALSELSESLELDDKSGTVVKRRKRRTRRQVVPSVEDESHRVRVPGDYTKTSKLLAQSYDRWVECRTCKTWFLQHNSYLTRRECPRCERHSMLYGFQWPKTDKDGPLDDEERVMDHRTVHRFLYPEEEARISRRDRGVSFGVTPTPELSEPRTETEDSEACDERRNTRASRRRTQSLRMTM

Protein

Histone-lysine N-methyltransferase set9: set9

Gene

set9

Protein

Histone-lysine N-methyltransferase set9

Organism

Aspergillus oryzae (strain ATCC 42149 / RIB 40)

Length

625 amino acids

Function

Histone methyltransferase that specifically methylates 'Lys-20' of histone H4.

Similarity

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.

Mass

70.383 kDa

Sequence

MPSSKARDSPSVERRDRLTLAKLASYDDVATDALVDRAYFWTNTRKNRTKYIPVRGVHEDDVARILLHEVIVAKDSAQAEKQLLAMSGMKKYLAKLPNDREKEWFRRHLRKYIQMYLPDSPFEVTTTNRYTITEHEAAICARKFIKQGQEIKYLSGTLVPMTREEEQELDLKRKDFSIVMSSRRKTPSFFLGPARFANHDCNANGRLVTRGSEGMQVVATRDIYIGEEITVSYGDDYFGIDNCECLCLTCERAVRNGWAPHVDSEEGSSKASTPALNDEAISNDSLLSPRKRKHHLDSDSDISPSSTPRKRSKFTRQSSKLRSAVSLADFAPVGSGSDNPPPQAETSIVPETTGAASITNDTIVPASGSAVEVSQASATDCDSSPSLEADESHHSSTSTTPTSIGDVKIKVEDTVEASLTESASATHITLSITGQPHNDRHPPGTDNDMLSELSEITDNPQKPKRSRGSRWKHGVVPSVEEESHRVRVPGDYTKTSKLLAQAYDRWVDCHTCNVWFVQHNSYLTRRECPRCERHSMLYGFRWPKTDKEGSMDDEERVMDHRTVHRFLYPEEEARISRKDRGVSFGVTPTPELSEPRTETEDSEACDDRRNTRASRTRTRSLRMTM

Protein

Histone-lysine N-methyltransferase set9: set9

Gene

SET9

Protein

Histone-lysine N-methyltransferase SET9

Organism

Coccidioides immitis (strain RS)

Length

624 amino acids

Function

Histone methyltransferase that specifically methylates 'Lys-20' of histone H4.

Similarity

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.

Mass

70.34 kDa

Sequence

MAPTPPPKQKGKLTLAQLAAYDDIVTDALVDRAFFWTKIRKNRPKYFAVRGVVEDDVTSILLHDVIVAKDVIKAEKSLLNLSGLRKYVETLKSDKEKEWFRRHLRKYIAIYLPDCPFEVTTTNRYTITTHEAALSARKFIRTGDTIKHLSGTLVAITPEEEKTLDLTRRDFSIVMSSRKKTPSLFLGPARFSNHDCNPNARLVTKGSEGMEIVAIRDISIGEEITVSYGENYFGVDNCECLCHTCELSLSNGWSPGGPPEHDSRASTPETTEHQEKSSSGSEKRKSPPESPSHPSEDMPSKRPKFENILNLRLEISPPSSPDPIAEPLITVNGGLRALRSHFASLAGKSDLRHFQKPHSNFISASSSSDQTSCSLCPDDEAPTSTRSTSATSISDSNVQVKTEPTVEQQPRASSETAPKTISGDHGLHVQDIIRDNDESDLSDLSASWEINDREMTAVKREPVKKKKRKRKSSIIPTIEHEAPKARTPGDYTKTPKLLAQRYDRWVDCQTCNAWFVQGDAYLTRKECPRCERHSKLYGYRWPKTDREGRNDTEERVMDHRTIHRFLRTEDEARVQRRGRGVSHATSPTPDVSENKTETDASEFGDERRLTRSLRRARSSLRLAI

Protein

Histone-lysine N-methyltransferase SET9: SET9

Gene

set9

Protein

Histone-lysine N-methyltransferase set9

Organism

Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)

Length

622 amino acids

Function

Histone methyltransferase that specifically methylates 'Lys-20' of histone H4.

Similarity

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.

Mass

69.939 kDa

Sequence

MPSAKKRDSPSVDRRDRLTLAKLASYDDIATDALVDRAYFWTNTRKNRTKYNPMRGIVDDDVARVLLHDVIVAKDLAKAERELLAMSGLKKFMARLPNNREKDWFRRHLRKYIQMYLPDSPFEITTTNRYTITEYEAAVCARKFIKQGQEIKYLSGTLVPMTREEERDLDLKRKDFSIVMSSRKKTPSFFLGPARFANHDCNANGKLVTRGSEGMQVVATRDIYIGEEITVSYGDDYFGIDNCECLCLTCERLVRNGWAPHVPSEPQSKASTPALNDDTLSTDSHVSSKKRKFAPDSDIETSAPSTPCKRGKFVRQSSKLKSEVSFLEVATSIEQPAGPSPVCNGSDMGALGNSTVESDNDKAVDPALPSPPADSPPSTAANESERSSTSTTATSVCDAAVKIKVEETIEQSAEKVSALSEANVELPTTSLRSGSTEGDTKLELSDQPSTLKQGSIGSNRKERRKSRGKPLVVESVEAERQLVRVPGDYTKTSKLLAQTYDRWVDCHTCNAWFVQHDSYLTRRECPRCERHSMLYGYRWPKTDKEGPSDDEERVMDHRTVHRFLYPEEEALISRKDRGVSFGVTPTPELSEPRTETEGSEGCEDRRTTRASRRRTRSLRMTM

Protein

Histone-lysine N-methyltransferase set9: set9

Gene

set9

Protein

Histone-lysine N-methyltransferase set9

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

441 amino acids

Function

Histone methyltransferase that specifically methylates 'Lys-20' of histone H4. H4 'Lys-20' methylation is apparently not involved in the regulation of gene expression or heterochromatin function but participates in DNA damage response by giving a 'histone mark' required for the recruitment of the checkpoint protein Crb2 to sites of DNA damage.

Similarity

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.

Mass

51.014 kDa

Sequence

MRQTNTHLETFSLFDDVCTCLLVDKVFYWSQIHKVRKLVDRSIERMESCSIINIITKYIIEQTDLDQAAKNILQFRELDPLLRRLSSTSLLAFTRHLKYYLSLYLPSCKFEICSTNQYFSSSKPEACVIARESINAGEDITDLCGTIIKLSPKEERNIGIGKDFSILHSSRLDSMCLFLGPARFVNHDCNANCRFNTSGKRIWLRCVRDIKPGEEITTFYSSNYFGLENCECLCVSCERMGINGFKKLFHTSATSTSCSSKSSSDVSDLSSLPQSNRYVISEEDRSFLNIWDSGGELSDASSSDLDEEFSLFIPRHKKRVWSREKRLLSEMAITNHSPLLNVDDYRKFREDLWKKRHGKRKVYQCSNCSQTFINEDIQNSSAFCPKCIRHSKLFSLPWPCRHKVNRELKLEKEKEINTKRNLVTSSHSMSLRHKKAVDYQS

Protein

Histone-lysine N-methyltransferase set9: set9